SIMULTANEOUS DETERMINATION OF FLURBIPROFEN AND PANTOPRAZOLE IN BULK AND PHARMACEUTICAL DOSAGE FORM BY UV SPECTROPHOTOMETER

Objective: A simple, rapid, precise and accurate spectrophotometric method has been developed for determination of Flurbiprofen and Pantoprazole by simultaneous equation method in combined dosage form Methods: The 6.8 pH phosphate buffer was selected as solvent for developing spectral characteristics of both drugs. The method was validated for recovery studies. Results: The λmax of Flubiprofen was found to be 230 nm and Pantoprazole was found to be 270 nm. The method obeyed Beer's law in the concentration range of 10-100 μg/ml for Flurbiprofen and 10-100 μg/ml for Pantoprazole. The percentage recovery of Flubiprofen was found to be 99.16 and Pantoprazole was found to be 99.46. Conclusion: The proposed method was validated and can be used for analysis of combined tablet formulation containing Flurbiprofen and Pantoprazole

A Novel Approach to Communicate Secret Message Between Users Using Sponge Function Technique on NTRU

This paper presents a novel approach for a (key distribution) for secret message communication among a group (G). In order to increase security to distribute secret message (key), we introduce sponge functions using these at a specific permutation. We generate a key and distribute this key using (PKCS)(public key crypto systems), the absorbing, squeezing functions are used. In this paper an introduction part which briefs regarding sponge functions, key distribution centre, group communication and NTRU, key generation authentication, in literature review we describe about the research states of sponge functions, lightweight hash functions-KDC – NTRU. In proposed work we propose how the group communication establishes registration of users, entry and exit of a user. The encryption and decryption algorithm are used between sender and receiver. The entire proposed work is verified in VHDL and ‘MATLABS'. doi: http://dx.doi.org/10.12777/ijse.4.2.2013.44-51 [How to cite this article: Varaprasad, S., Rao, K. V., & Avadhani, P. S. (2013). A Novel Approach to Communicate Secret Message between Users Using Sponge Function Technique on NTRU. INTERNATIONAL JOURNAL OF SCIENCE AND ENGINEERING, 4(2), 44-51; doi: http://dx.doi.org/10.12777/ijse.4.2.2013.44-51

LIQUISOLID TECHNIQUE: A NOVEL APPROACH FOR DOSAGE FORM DESIGN

The liquisolid technique is a novel approach for delivery of drugs through the oral route. This technique is suitable for poorly soluble or water insoluble drugs, highly permeable drugs (BCS Class II drugs) and also for immediate or sustained release formulations. It is a novel "Powder Solution Technology" that involves absorption and adsorption efficiencies, making use of liquid medications, drug suspensions admixed with suitable carriers, coating materials and formulated into free flowing, dry looking, non-adherent and compressible powder forms. The design of liquisolid systems are mainly intended for enhancement of solubility, dissolution rate and bioavailability of poorly water-soluble and highly lipophilic drugs. Improvement in bioavailability may be due to increased surface area, increased aqueous solubility and increased the wettability of the drug. Liquisolid technique also has the potential to be optimized for the reduction of drug dissolution rate and thereby production of sustained release systems. Overall, liquisolid technique is a most promising and novel technique for enhancing the dissolution and bioavailability of poorly water soluble drugs and sustaining drug release from tablet matrices. The current review mainly focuses on theory and applicability of liquisolid compact technique towards solubility or bioavailability enhancement. Different carriers, solvents and coating materials employed are elucidated. Literature reports on the applicability of liquisolid compact techniques over a wide range of pharmaceutical formulations are also explicated

REFU: Redundant Execution with Idle Functional Units, Fault Tolerant GPGPU architecture

The General-Purpose Graphics Processing Units (GPGPU) with energy efficient execution are increasingly used in wide range of applications due to high performance. These GPGPUs are fabricated with the cutting-edge technologies. Shrinking transistor feature size and aggressive voltage scaling has increased the susceptibility of devices to intrinsic and extrinsic noise leading to major reliability issues in the form of the transient faults. Therefore, it is essential to ensure the reliable operation of the GPGPUs in the presence of the transient faults. GPGPUs are designed for high throughput and execute the multiple threads in parallel, that brings a new challenge for the fault detection with minimum overheads across all threads. This paper proposes a new fault detection method called REFU, an architectural solution to detect the transient faults by temporal redundant re-execution of instructions using the idle functional execution units of the GPGPU. The performance of the REFU is evaluated with standard benchmarks, for fault free run across different workloads REFU shows mean performance overhead of 2%, average power overhead of 6%, and peak power overhead of 10%

All-optical control of ferromagnetic thin films and nanostructures

The interplay of light and magnetism has been a topic of interest since the original observations of Faraday and Kerr where magnetic materials affect the light polarization. While these effects have historically been exploited to use light as a probe of magnetic materials there is increasing research on using polarized light to alter or manipulate magnetism. For instance deterministic magnetic switching without any applied magnetic fields using laser pulses of the circular polarized light has been observed for specific ferrimagnetic materials. Here we demonstrate, for the first time, optical control of ferromagnetic materials ranging from magnetic thin films to multilayers and even granular films being explored for ultra-high-density magnetic recording. Our finding shows that optical control of magnetic materials is a much more general phenomenon than previously assumed. These results challenge the current theoretical understanding and will have a major impact on data memory and storage industries via the integration of optical control of ferromagnetic bits.Comment: 21 pages, 11 figure

First report of the lesion nematode Pratylenchus brachyurus on groundnut in India.

In India information on nematode pests of groundnut and their damage is very scanty and is largely restricted to root-knot nematodes, Meloidogyne fa vanica and M. arenaria, and stunt nematode, Tylenchorhynchus brevilineatus. In 1987 and 1988, we conducted preliminary surveys in some groundnut producing regions of Andhra Pradesh,....

Experimental and numerical studies on the damage behavior of open hole CFRP composite specimen subjected to compression

In this work, the progressive failure of open hole composite specimen subjected to compression is studied. CFRP laminates of various stacking sequence (unidirectional, cross-ply, quasi-isotropic) with a circular hole are fabricated and tested under compressive loading. An anti-buckling compression fixture is used to prevent buckling of specimens. In this work, a unified experimental approach comprising of digital image correlation (DIC), acoustic emission (AE) and strain gauge are used to study the damage mechanisms of open hole CFRP specimen under compression. DIC is employed to capture the surface strain field near the hole of the CFRP specimen. AE is used to study the initiation and progression of various damage modes in the CFRP specimen. AE parameters are then used to classify the various damage events in uni-directional, cross-ply and quasi-isotropic laminates. Strain gauges are also employed to capture the failure strain information close to the hole. Subsequently, fractography studies are carried out to ascertain the occurrence of various damage modes in the specimen. In additon, finite element (FE) simulation of the progressive damage failure of the open hole CFRP specimen is done using ABAQUS software. Three-dimensional brick elements (C3D8R) are used to simulate the compression failure in the CFRP specimen. A VUMAT subroutine is coded to study the matrix compression and fiber kink failure based on Pinho’s damage model. Numerical results obtained from FE simulations are then compared with experimental observations, and the accuracy of the FE model is validated

Some barium titanate based dielectrics

Some new potential dielectric materials have been made through the cross-substitution of Ba2+ by a 1:1 molar combinations of tri-(La3+) and mono-valent (Li+, Na+, K+) ions at the Ba2+ site in BaTiO3. Chemical analysis shows that compositions in the potassium series are about 6·1% deficient in their K2O content and exhibit interesting dielectric relaxations. The cross-substitution has lowered theT c down to room temperature. The disorder in the larger 'A' cation sublattice of the three systems has been established by infra-red and x-ray data. This leads to microscopic compositional variations, which in turn can account for the diffuseness of the dielectric anomalies observed in the barium titanate-rich compositions (0≤x≤0·3)