Acute exacerbations of chronic obstructive lung disease

Akutne egzacerbacije kronične opstruktivne plućne bolesti (KOPB) definirane su akutnim pogoršanjem respiratornih simptoma koje zahtijevaju dodatno liječenje, a pritom stupanj zaduhe nadmašuje uobičajenu razinu uz povećan volumen i/ili purulenciju iskašljaja. Najčešći uzrok akutnih egzacerbacija KOPB-a su virusne, nešto rjeđe bakterijske ili miješane infekcije. Bolesnici s fenotipom učestalog egzacerbatora koji su tijekom prethodnih dvanaest mjeseci liječeni od najmanje dvije umjerene ili jedne teške egzacerbacije imaju znatno lošiju kvalitetu života i ubrzano propadanje plućne funkcije. Više od 80% akutnih egzacerbacija moguće je liječiti ambulantno bronhodilatatorima, oralnim kortikosteroidima i/ili antibiotikom.Acute exacerbations of chronic obstructive lung disease (COPD) are defined as episodes of increased respiratory symptoms, particularly dyspnea, sputum volume and purulence, requiring additional therapy. Acute exacerbations are mostly induced by viral, less often bacterial or mixed infections. Patients with two or more exacerbations treated in the outpatient department (or at least one hospitalisation for acute exacerbation) are considered as frequent exacerbators – the phenotype associated with poorer quality of life and accelerated loss of lung function. More than 80% of acute exacerbations can be treated in the outpatient setting with bronchodilators, short-course of oral corticosteroids and/or antibiotics

Acute exacerbations of chronic obstructive lung disease

Akutne egzacerbacije kronične opstruktivne plućne bolesti (KOPB) definirane su akutnim pogoršanjem respiratornih simptoma koje zahtijevaju dodatno liječenje, a pritom stupanj zaduhe nadmašuje uobičajenu razinu uz povećan volumen i/ili purulenciju iskašljaja. Najčešći uzrok akutnih egzacerbacija KOPB-a su virusne, nešto rjeđe bakterijske ili miješane infekcije. Bolesnici s fenotipom učestalog egzacerbatora koji su tijekom prethodnih dvanaest mjeseci liječeni od najmanje dvije umjerene ili jedne teške egzacerbacije imaju znatno lošiju kvalitetu života i ubrzano propadanje plućne funkcije. Više od 80% akutnih egzacerbacija moguće je liječiti ambulantno bronhodilatatorima, oralnim kortikosteroidima i/ili antibiotikom.Acute exacerbations of chronic obstructive lung disease (COPD) are defined as episodes of increased respiratory symptoms, particularly dyspnea, sputum volume and purulence, requiring additional therapy. Acute exacerbations are mostly induced by viral, less often bacterial or mixed infections. Patients with two or more exacerbations treated in the outpatient department (or at least one hospitalisation for acute exacerbation) are considered as frequent exacerbators – the phenotype associated with poorer quality of life and accelerated loss of lung function. More than 80% of acute exacerbations can be treated in the outpatient setting with bronchodilators, short-course of oral corticosteroids and/or antibiotics