Participant and Sex Network Characteristics Associated with Having a Black Sex Partner, Having a Partner with at Least 2 Age Category Difference, and Having SDUI in the Last 6 Months among Community-Recruited Participants Stratified by Self-Reported HIV Serostatus of Participant, Multivariate GEE Models (N = 4,449 Partners).

<p>GEE: Generalized estimating equation, SDUI: serodiscordant/serostatus unknown unprotected anal and/or vaginal intercourse, AOR: Adjusted odds ratio, 95% CI: 95% Confidence Interval, Ref: Reference, NA: Not applicable as there were no observations detected.</p><p>Participant and Sex Network Characteristics Associated with Having a Black Sex Partner, Having a Partner with at Least 2 Age Category Difference, and Having SDUI in the Last 6 Months among Community-Recruited Participants Stratified by Self-Reported HIV Serostatus of Participant, Multivariate GEE Models (N = 4,449 Partners).</p

Sex Partner Characteristics, Condom Use, and HIV Serostatus Disclosure of Community-Recruited Black MSM, Partner-Level Data (N = 4,449 Partners).

<p>Numbers may not add up to column total due to missing data.</p><p>^a P-value <0.05 for all variables compared by study city. Site-specific differences may be reflective of different recruitment strategies used by the study sites, rather than of overall differences between cities.</p><p>Sex Partner Characteristics, Condom Use, and HIV Serostatus Disclosure of Community-Recruited Black MSM, Partner-Level Data (N = 4,449 Partners).</p

Sociodemographics, Risk Behaviors, and Sexual Network Characteristics of Community-Recruited Black MSM Stratified by Self-Reported HIV Serostatus and Age, Participant- and Network-Level Data (N = 1,349 Participants).

<p>Numbers may not add up to total due to missing data.</p><p>NA: Not applicable.</p><p>^a P-value <0.05 for all variables when compared by study city, except for self-reported HIV serostatus at enrollment. Site-specific differences may be reflective of different recruitment strategies used by the study sites, rather than of overall differences between cities.</p><p>^b P-value comparing self-reported HIV-positive men with self-reported HIV-negative men</p><p>^c SDUI: serodiscordant/serostatus unknown unprotected anal and/or vaginal intercourse</p><p>^d Age category difference is based on the following age categorical variables of the sexual partners in the social and sexual network inventory: ≤17 years, 18–20, 21–25, 25–30, 30–40, 40–50, 50–60, and ≥60</p><p>Sociodemographics, Risk Behaviors, and Sexual Network Characteristics of Community-Recruited Black MSM Stratified by Self-Reported HIV Serostatus and Age, Participant- and Network-Level Data (N = 1,349 Participants).</p

HIV incidence rates with time-dependent Cox proportional hazard models among Black MSM, HPTN 061.

<p>HR =  hazard ratio; REF =  reference group: URAI = unprotected receptive anal intercourse; UIAI =  unprotected insertive anal intercourse; UAI =  unprotected anal intercourse.</p

Percent with sexually transmitted infections and self-reported risk behaviors by study visit and age group.

<p>Solid lines ≤30 years of age, dashed lines >30 years of age. Red squares: 2+ male partners; Blue triangles: Unprotected receptive anal intercourse with positive or unknown status male partners; Green circles: Sexually transmitted infections; Orange stars: HIV- positive male partners.</p

Demographic characteristics and baseline behaviors of HIV-uninfected Black MSM, HPTN 061 (n = 1164).

*<p>N may not add to total due to missing values.</p>**<p>based on study testing for syphilis and urethral/rectal gonorrhea and Chlamydia. URAI = unprotected receptive anal intercourse; UIAI =  unprotected insertive anal intercourse.</p

Flow diagram of study sample, HPTN 061*.

<p>*Men were categorized as previously diagnosed (prior HIV diagnosis) based on self-report or retrospective detection of antiretroviral drugs in samples from the enrollment visit (see Methods). The newly diagnosed group included three men who had acute HIV infection at enrollment.</p

Sociodemographic, behavioral, and health characteristics of participants (N = 80).

<p>Sociodemographic, behavioral, and health characteristics of participants (N = 80).</p

Unadjusted Cox proportional hazards model for time to first CD4 ≤ 350 and time to composite disease progression endpoint.

<p>Unadjusted Cox proportional hazards model for time to first CD4 ≤ 350 and time to composite disease progression endpoint.</p

Linear mixed effects model comparing HIV-1 RNA (log₁₀) and CD4 T-cell counts between the first result 90 days or more after the estimated HIV seroconversion date (intercept) and the 12-month visit (slope) by study arm.

<p>Linear mixed effects model comparing HIV-1 RNA (log₁₀) and CD4 T-cell counts between the first result 90 days or more after the estimated HIV seroconversion date (intercept) and the 12-month visit (slope) by study arm.</p