The MeerKAT Galaxy Cluster Legacy Survey: I. Survey overview and highlights

Please abstract in the article.The South African Radio Astronomy Observatory (SARAO), the National Research Foundation (NRF), the National Radio Astronomy Observatory, US National Science Foundation, the South African Research Chairs Initiative of the DSI/NRF, the SARAO HCD programme, the South African Research Chairs Initiative of the Department of Science and Innovation.http://www.aanda.orghj2022Physic

Eliciting antibodies in chickens to human dimeric IgA removal of factors from human colostrum depressing anti IgA antibody production

Contrary to expectation chickens did not readily elicit antibodies to IgA dimers when untreated human colostrum was used as antigen. When colostrum was fractionated by means of a column of 8% granulated agarose equilibrated with 10 mM phosphate buffer, pH 7.2, a major and a minor fraction were obtained. The major or '1st fraction' consisted of two components with sedimentation coefficients of 10.9 S and 14.1 S, respectively. The minor or '2nd fraction' consisted of components of S values ranging from 2 to 6 and small amounts of 10.9 and 14.1 S material. When chickens were immunized with the '1st fraction' antibodies to dimeric IgA were produced. When the '1st and 2nd fractions' of the column were remixed and used for immunization of chickens, the immune response was poor as when the chickens were injected with untreated colostrum. An immuno-depressing agent in colostrum was indicated. When rabbits were immunized with clarified human colostrum, antibodies against five antigens were elicited, one of the antigens being dimeric IgA. The immuno-depressing agent is therefore not universal. The purified agent suppressed antibody formation in chickens against the haemocyanin of Jasus lalandii. The 'activity' is therefore not specific for IgA and the remaining four antigens in human colostrum. The purified component is a glyco-protein with a hexose content in excess of 10%. The derivatized sugars prepared from it were shown by gas liquid chromatography to be an equimolar mixture of galactose, mannose and fucose. The molecular weight (Mr) of the purified component was found to be 72,000 by sedimentation and diffusion and 80,000 by SDS page using Mr reference standards. The properties of the immuno-suppressor strongly suggest that it is the secretory piece of dimeric IgA.Articl

Natural occurrence of fusarin C, a mutagen produced by Fusarium moniliforme, in corn

Fusarin C is a highly mutagenic compound produced by strains of Fusarium moniliforme and exhibits a mutagenic activity comparable with that of aflatoxin B1 and sterigmatocystin. All the isolates of F. moniliforme and Fusarium graminearum tested were shown to produce fusarin C in culture, while none of the isolates of F. moniliforme var. subglutinans produced fusarin C. Chemical analyses of a sample of moldy home-grown corn from Butterworth, Transkei, indicated that fusarin C occurs naturally in both hand-selected visibly Fusarium infected and "healthy" corn kernels. © 1984 American Chemical Society.Articl

The status quo of enterprise architecture implementation in South African financial services companies

This article presents the findings of research that was conducted amongst Enterprise Architecture (EA) practitioners in the South African financial services sector. Due to the duration and cost implications of EA projects, factors that contribute to the success and failure of EA initiatives need to be investigated and identified. The research was largely based on a similar international study that was conducted by Schekkerman (2004b). A number of aspects of EA were investigated, including the place of EA in organisational and strategic governance, the EA architects, practices and processes, as well as the measurement of EA initiatives. Key findings from the study were that South African companies surveyed demonstrated lower levels of maturity in their approaches to the management of EA practices and processes; also identified were significant differences in the approach in South African respondents compared to international studies with respect to ownership of EA initiatives and the types of EA frameworks and modelling techniques in use

The status quo of enterprise architecture implementation in South African financial services companies

This article presents the findings of research that was conducted amongst Enterprise Architecture (EA) practitioners in the South African financial services sector. Due to the duration and cost implications of EA projects, factors that contribute to the success and failure of EA initiatives need to be investigated and identified. The research was largely based on a similar international study that was conducted by Schekkerman (2004b). A number of aspects of EA were investigated, including the place of EA in organisational and strategic governance, the EA architects, practices and processes, as well as the measurement of EA initiatives. Key findings from the study were that South African companies surveyed demonstrated lower levels of maturity in their approaches to the management of EA practices and processes; also identified were significant differences in the approach in South African respondents compared to international studies with respect to ownership of EA initiatives and the types of EA frameworks and modelling techniques in use

Natural occurrence of fusarin C, a mutagen produced by Fusarium moniliforme, in corn

Fusarin C is a highly mutagenic compound produced by strains of Fusarium moniliforme and exhibits a mutagenic activity comparable with that of aflatoxin B1 and sterigmatocystin. All the isolates of F. moniliforme and Fusarium graminearum tested were shown to produce fusarin C in culture, while none of the isolates of F. moniliforme var. subglutinans produced fusarin C. Chemical analyses of a sample of moldy home-grown corn from Butterworth, Transkei, indicated that fusarin C occurs naturally in both hand-selected visibly Fusarium infected and "healthy" corn kernels. © 1984 American Chemical Society.Articl

A landscape-scale assessment of the long-term integrated control of an invasive shrub in South Africa

The control of invasive alien plants often involves the integration two or more approaches, including mechanical clearing, the application of herbicides, burning, and biological control. More than one species of invasive plant can threaten the same area, which necessitates prioritization in the allocation of scarce resources to support the control of different species. This paper describes the integrated control of the invasive shrub Hakea sericea over four decades in South Africa. The species is widespread across an area of approximately 800 x 200 km, and occurs mainly in rugged, inaccessible and fire-prone mountain areas. The species is serotinous, and produces copious amounts of seed that are wind dispersed after fires. We present a brief history of the control measures which included a combination of felling and burning, augmented by biological control. We used data from two surveys, 22 years apart, to assess changes in distribution and density of the species. The assessment suggested that the overall distribution of the species was reduced by 64%, from ~530,000 to ~190,000 ha between 1979 and 2001. The species either decreased in density, or was eliminated from 492,113 ha, while it increased in density, or colonised 107,192 ha. We conclude that initial programs of mechanical clearing were responsible for reducing the density and extent of infestations, and biological control was largely responsible for the failure of the species to re-colonize cleared sites, or to spread to new areas following unplanned wildfires. We propose that a significant portion of the resources used for clearing Hakea in the past can be reallocated to mechanical control efforts against other invasive species (such as alien pines) for which effective biological control options are not available, provided that sufficient resources are allocated to ensure the widespread and effective implementation of all biological control agents to maintain the advances reported on here.Centre of Excellence for Invasion Biolog

Gene symbol: SLC40A1. Disease: primary iron overload.

[No abstract available]Articl

Gene symbol: DCYTB/CYBRD1. Disease: primary iron overload.

[No abstract available]Articl