4,899 research outputs found
PRS26 A Cost-Effectiveness Analysis of Sildenafil for the Treatment of Pulmonary Arterial Hypertension in Europe
Identifying single electron charge sensor events using wavelet edge detection
The operation of solid-state qubits often relies on single-shot readout using
a nanoelectronic charge sensor, and the detection of events in a noisy sensor
signal is crucial for high fidelity readout of such qubits. The most common
detection scheme, comparing the signal to a threshold value, is accurate at low
noise levels but is not robust to low-frequency noise and signal drift. We
describe an alternative method for identifying charge sensor events using
wavelet edge detection. The technique is convenient to use and we show that,
with realistic signals and a single tunable parameter, wavelet detection can
outperform thresholding and is significantly more tolerant to 1/f and
low-frequency noise.Comment: 11 pages, 4 figure
Spitzer IRAC Imaging of the Relativistic Jet from Superluminal Quasar PKS 0637-752
Emission from the relativistic jet located at hundreds of kpc from the core
of the superluminal quasar PKS 0637-752 was detected at 3.6 and 5.8 microns
with the Infrared Array Camera (IRAC) on the Spitzer Space Telescope. The
unprecedented sensitivity and arcsecond resolution of IRAC allows us to explore
the mid-infrared emission from kiloparsec-scale quasar jets for the first time.
The mid-infrared flux from the jet knots, when combined with radio and optical
fluxes, confirms a synchrotron origin of the radio-to-optical emission and
constrains very well the high energy end of the nonthermal electron
distribution. Assuming the X-rays are produced in the relativistically moving
knots via inverse Compton scattering of cosmic microwave background (CMB)
radiation, the infrared observation puts constraints on the matter content of
the quasar extended jet. Specifically, pure electron-positoron pair jet models
are unfavorable based on the lack of an infrared bump associated with ``bulk
Comptonization'' of CMB photons by an ultrarelativistic jet.Comment: 4 pages, 3 figures; accepted for publication in ApJ Letter
Whey- vs Casein-Based Enteral Formula and Gastrointestinal Function in Children With Cerebral Palsy.
Objectives: Children with severe cerebral palsy (CP) commonly have gastrointestinal (GI) dysfunction. Whey-based enteral formulas have been postulated to reduce gastroesophageal reflux (GOR) and accelerate gastric emptying (GE). The authors investigated whether whey-based (vs casein-based) enteral formulas reduce GOR and accelerate GE in children who have severe CP with a gastrostomy and fundoplication.
Methods: Thirteen children received a casein-based formula for 1 week and either a 50% whey whole protein (50% WWP) or a 100% whey partially hydrolyzed protein (100% WPHP) formula for 1 week. Reflux episodes, gastric half-emptying time (GE t1/2), and reported pain and GI symptoms were measured.
Results: Whey formulas emptied significantly faster than casein (median [interquartile range (IQR)] GE t1/2, 33.9 [25.3-166.2] min vs 56.6 [46-191] min; P = .033). Reflux parameters were unchanged. GI symptoms were lower in children who received 50% WWP (visual analog symptom score, median [IQR], 0[0-11.8]) vs 100% WPHP (13.0 [2.5-24.8]) (P = .035).
Conclusion: This pilot study shows that in children who have severe CP with a gastrostomy and fundoplication, GE of the whey-based enteral formula is significantly faster than casein. The acceleration in GE does not alter GOR frequency, and there appears to be no effect of whey vs casein in reducing acid, nonacid, and total reflux episodes. The results indicate that enteral formula selection may be particularly important for children with severe CP and delayed GE. (JPEN J Parenter Enteral Nutr. 2012;36:118S-123S
Low-speed impact craters in loose granular media
We report on craters formed by balls dropped into dry, non-cohesive, granular
media. By explicit variation of ball density , diameter , and
drop height , the crater diameter is confirmed to scale as the 1/4 power of
the energy of the ball at impact:
. Against expectation, a different
scaling law is discovered for the crater depth:
. The scaling with properties of
the medium is also established. The crater depth has significance for granular
mechanics in that it relates to the stopping force on the ball.Comment: experiment; 4 pages, 3 figure
Tunable spin-selective loading of a silicon spin qubit
The remarkable properties of silicon have made it the central material for
the fabrication of current microelectronic devices. Silicon's fundamental
properties also make it an attractive option for the development of devices for
spintronics and quantum information processing. The ability to manipulate and
measure spins of single electrons is crucial for these applications. Here we
report the manipulation and measurement of a single spin in a quantum dot
fabricated in a silicon/silicon-germanium heterostructure. We demonstrate that
the rate of loading of electrons into the device can be tuned over an order of
magnitude using a gate voltage, that the spin state of the loaded electron
depends systematically on the loading voltage level, and that this tunability
arises because electron spins can be loaded through excited orbital states of
the quantum dot. The longitudinal spin relaxation time T1 is measured using
single-shot pulsed techniques and found to be ~3 seconds at a field of 1.85
Tesla. The demonstration of single spin measurement as well as a long spin
relaxation time and tunability of the loading are all favorable properties for
spintronics and quantum information processing applications.Comment: 4 pages, 3 figures, Supplemental Informatio
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