Uniparental maternal disomy 6 in a renal transplant patient.

Uniparental maternal disomy 6 in a renal transplant patient. van den Berg-Loonen EM, Savelkoul P, van Hooff H, van Eede P, Riesewijk A, Geraedts J. Tissue Typing Laboratory, University Hospital Maastricht, The Netherlands. HLA analysis of the family of a renal transplant patient revealed an extremely rare condition. On repeated typings the only demonstrable HLA antigens shown in the propositus were from the maternal haplotype, HLA-A11,-B46,-CW1,-DR14,-DQ1. No paternal antigens could be demonstrated either by serologic or by DNA-typing methods. A paternity investigation was carried out to exclude the possibility of the legal father not being the biological father. The results of this investigation showed a paternity index I = > 20000 and a fatherhood probability W = > 99.995%. Karyotyping of the patient showed two normal chromosomes 6 and no other chromosomal abnormalities. Maternal isodisomy was demonstrated from the analysis of polymorphic DNA markers, involving the short as well as the long arm of chromosome 6. These data are consistent with this patient having the first uniparental maternal disomy 6 reported (inheritance of two identical chromosome 6 haplotypes from the mother and none from the father)

O gênero Paradiacheopsis (Stemonitales, Myxomycetes) no Brasil The genus Paradiacheopsis (Stemonitales, Myxomycetes) in Brazil

Levantamento da diversidade de mixomicetos no Parque Estadual das Dunas do Natal, Unidade de Conservação de Mata de Duna Litorânea no Rio Grande do Norte e parte da Reserva da Biosfera da Mata Atlântica Brasileira, resultou no registro de Paradiacheopsis longipes Hoof & Nann.-Bremek., nova ocorrência para o Brasil e segunda para a Região Neotropical. Além de P. curitibana Hertel, conhecida apenas na localidade tipo, em Curitiba, PR, não se dispunha de registro de ocorrência de representantes do gênero para o Brasil. P. longipes é ilustrada e comentada quanto aos caracteres taxonômicos mais relevantes.<br>Slime molds diversity survey in the Parque Estadual das Dunas do Natal, a conservation area of coastal dune forest in Rio Grande do Norte and part of Biosphere reserve of Brazilian Atlantic Forest, resulted on the recording of Paradiacheopsis longipes Hoof & Nann.-Bremek., new occurrence for Brazil and second for the neotropical region. Besides P. curitibana Hertel, only known in the locality type, in Curitiba, PR, this genus was not registered before in Brazil. P. longipes is illustrated and comments about the most relevant taxonomic characters are made