13,400 research outputs found

    Monotonicity and error bounds for networks of Erlang loss queues

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    Networks of Erlang loss queues naturally arise when modelling finite communication systems without delays, among which, most notably are (i) classical circuit switch telephone networks (loss networks) and (ii) present-day wireless mobile networks. Performance measures of interest such as loss probabilities or throughputs can be obtained from the steady state distribution. However, while this steady state distribution has a closed product form expression in the first case (loss networks), it does not have one in the second case due to blocked (and lost) handovers. Product form approximations are therefore suggested. These approximations are obtained by a combined modification of both the state space (by a hypercubic expansion) and the transition rates (by extra redial rates). It will be shown that these product form approximations lead to (1) upper bounds for loss probabilities and \ud (2) analytic error bounds for the accuracy of the approximation for various performance measures.\ud The proofs of these results rely upon both monotonicity results and an analytic error bound method as based on Markov reward theory. This combination and its technicalities are of interest by themselves. The technical conditions are worked out and verified for two specific applications:\ud (1)• pure loss networks as under (2)• GSM networks with fixed channel allocation as under.\ud The results are of practical interest for computational simplifications and, particularly, to guarantee that blocking probabilities do not exceed a given threshold such as for network dimensioning

    Climate and terrain factors explaining streamflow response and recession in Australian catchments

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    Daily streamflow data were analysed to assess which climate and terrain factors best explain streamflow response in 183 Australian catchments. Assessed descriptors of catchment response included the parameters of fitted baseflow models, and baseflow index (BFI), average quick flow and average baseflow derived by baseflow separation. The variation in response between catchments was compared with indicators of catchment climate, morphology, geology, soils and land use. Spatial coherence in the residual unexplained variation was investigated using semi-variogram techniques. A linear reservoir model (one parameter; recession coefficient) produced baseflow estimates as good as those obtained using a non-linear reservoir (two parameters) and for practical purposes was therefore considered an appropriate balance between simplicity and explanatory performance. About a third (27–34%) of the spatial variation in recession coefficients and BFI was explained by catchment climate indicators, with another 53% of variation being spatially correlated over distances of 100–150 km, probably indicative of substrate characteristics not captured by the available soil and geology data. The shortest recession half-times occurred in the driest catchments and were attributed to intermittent occurrence of fast-draining (possibly perched) groundwater. Most (70–84%) of the variation in average baseflow and quick flow was explained by rainfall and climate characteristics; another 20% of variation was spatially correlated over distances of 300–700 km, possibly reflecting a combination of terrain and climate factors. It is concluded that catchment streamflow response can be predicted quite well on the basis of catchment climate alone. The prediction of baseflow recession response should be improved further if relevant substrate properties were identified and measured

    Ultrafast spectroscopy of single molecules

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    We present a single-molecule study on femtosecond dynamics in multichromophoric systems, combining fs pump-probe, emission-spectra and fluorescence-lifetime analysis. At the single molecule level a wide range of exciton delocalisation lengths and energy redistribution times is revealed. Next, two color pump-probe experiments are presented as a step to addressing ultrafast energy transfer in individual complexes

    The cerebellar (para)flocculus:A review on its auditory function and a possible role in tinnitus

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    The cerebellum is historically considered to be involved in motor control and motor learning. However, it is also a site of multimodal sensory and sensory-motor integration, implicated in auditory processing. The flocculus and paraflocculus are small lobes of the cerebellum, in humans located in the cerebellopontine angle. The last two decades, both structures have been a subject of interest in hearing loss and tinnitus research. The current review summarizes insights on the auditory function of the (para)flocculus and its contribution to hearing loss and tinnitus. This leads to the hypothesis of a feedback loop between the paraflocculus and the auditory cortex. Disruption of this loop may be instrumental in both maintaining tinnitus and reducing tinnitus. Although the research mostly has been performed in animals, the implications in humans are also discussed. If the (para)flocculus indeed comprises an auditory function and is part of a tinnitus-mechanism, this would potentially open up new treatment options that involve direct intervention at the (para)flocculus

    Selection of an appropriately simple storm runoff model

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    An appropriately simple event runoff model for catchment hydrological studies was derived. The model was selected from several variants as having the optimum balance between simplicity and the ability to explain daily observations of streamflow from 260 Australian catchments (23–1902 km<sup>2</sup>). Event rainfall and runoff were estimated from the observations through a combination of baseflow separation and storm flow recession analysis, producing a storm flow recession coefficient (<i>k</i><sub>QF</sub>). Various model structures with up to six free parameters were investigated, covering most of the equations applied in existing lumped catchment models. The performance of alternative structures and free parameters were expressed in Aikake's Final Prediction Error Criterion (FPEC) and corresponding Nash-Sutcliffe model efficiencies (NSME) for event runoff totals. For each model variant, the number of free parameters was reduced in steps based on calculated parameter sensitivity. The resulting optimal model structure had two or three free parameters; the first describing the non-linear relationship between event rainfall and runoff (<i>S</i><sub>max</sub>), the second relating runoff to antecedent groundwater storage (<i>C</i><sub>Sg</sub>), and a third that described initial rainfall losses (<i>L</i><sub>i</sub>), but which could be set at 8 mm without affecting model performance too much. The best three parameter model produced a median NSME of 0.64 and outperformed, for example, the Soil Conservation Service Curve Number technique (median NSME 0.30–0.41). Parameter estimation in ungauged catchments is likely to be challenging: 64% of the variance in <i>k</i><sub>QF</sub> among stations could be explained by catchment climate indicators and spatial correlation, but corresponding numbers were a modest 45% for <i>C</i><sub>Sg</sub>, 21% for <i>S</i><sub>max</sub> and none for <i>L</i><sub>i</sub>, respectively. In gauged catchments, better estimates of event rainfall depth and intensity are likely prerequisites to further improve model performance

    A protein–DNA docking benchmark

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    We present a protein–DNA docking benchmark containing 47 unbound–unbound test cases of which 13 are classified as easy, 22 as intermediate and 12 as difficult cases. The latter shows considerable structural rearrangement upon complex formation. DNA-specific modifications such as flipped out bases and base modifications are included. The benchmark covers all major groups of DNA-binding proteins according to the classification of Luscombe et al., except for the zipper-type group. The variety in test cases make this non-redundant benchmark a useful tool for comparison and development of protein–DNA docking methods. The benchmark is freely available as download from the internet
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