721 research outputs found
Physiological traits for screening drought resistance in barley
Evaluates critically a number of physiological traits which may be related to drought resistance in cereals and examines the feasibility of using these screening techniques in selecting more drought resistant genotypes of barley for South AustraliaThesis (M.Ag.Sc.) -- University of Adelaide, Dept. of Plant Science, 199
A Systems Biology Approach to the Development of Commercial Bioprocesses: 1,4-butanediol and beyond
Production of biobased chemicals by fermentation at competitive titer, rate, and yield involves optimizing the cellular resources normally devoted to biomass formation and directing them towards product formation. Systems and synthetic biology tools are the key to surmounting these challenges. As an example success of this approach, Genomatica has developed a complete bioprocess for commercial scale production of 1,4-butanediol (BDO) from carbohydrate feedstocks. BDO is a chemical intermediate (\u3e 3B lbs/yr) that goes into a variety of products including automotive parts and apparel, and is currently produced commercially through energy-intensive petrochemical processes. Systems biology, diagnostic āomicsā experiments, and novel synthetic biology tools will be emphasized to highlight the importance of rational metabolic engineering approaches for achieving high level strain performance
A Systems Biology Approach to the Development of Commercial Bioprocesses: 1,4-butanediol and beyond
Production of biobased chemicals by fermentation at competitive titer, rate, and yield involves optimizing the cellular resources normally devoted to biomass formation and directing them towards product formation. Systems and synthetic biology tools are the key to surmounting these challenges. As an example success of this approach, Genomatica has developed a complete bioprocess for commercial scale production of 1,4-butanediol (BDO) from carbohydrate feedstocks. BDO is a chemical intermediate (\u3e 3B lbs/yr) that goes into a variety of products including automotive parts and apparel, and is currently produced commercially through energy-intensive petrochemical processes. Systems biology, diagnostic āomicsā experiments, and novel synthetic biology tools will be emphasized to highlight the importance of rational metabolic engineering approaches for achieving high level strain performance
Sustainability drivers and practices in Vietnamese manufacturing: a multiple-case study through the lens of the Sustainability Marketing Mix
The present rate and extent of the Southeast Asia region\u27s economic expansion, social disintegration, and environmental destruction necessitate additional academic research and industry action. The importance of exploring the Marketing function in the pursuit of sustainable development (SD) by the private sector has called for the disciplineās innovative ideas to address pressure from stakeholders not only on firmsā economic, but also social and environmental performance. Emerging economies, such as Vietnam, present dilemmas since rapid mass economic development aimed at lifting standards of living creates serious threats to social imbalance and environmental health. Although businesses in Vietnam have been increasingly recognising their role in contributing to SD, little is known about the driving forces of sustainability initiatives in Vietnamese manufacturing firms, and how they integrate sustainability practices from the marketingās viewpoint via its ten controllable elements designed for the purpose of achieving SD- the Sustainability Marketing Mix (SMM) which is an extension of the classic ā4Psā. The research aims to have a novel and timely contribution to the literature of the Marketing discipline and assist managers to improve their sustainability performance
Implicit and explicit selective attention to smoking cues in smokers indexed by brain potentials
Abstract
Substance use disorders are characterized by cognitive processing biases, such as automatically detecting and orienting attention towards drug-related stimuli. However, it is unclear how, when and what kind of attention (i.e. implicit, explicit) interacts with the processing of these stimuli. In addition, it is unclear whether smokers are hypersensitive to emotionally significant cues in general or to smoking-related cues in particular. The present event-related potential study aimed to enhance insight in drug-related processing biases by manipulating attention for smoking and other motivationally relevant (emotional) cues in smokers and non-smokers using a visual oddball task. Each of the stimulus categories served as a target (explicit attention; counting) or as a non-target (implicit attention; oddball) category. Compared with non-smokers, smokers' P300 (350-600 ms) was enhanced to smoking pictures under both attentional conditions. P300 amplitude did not differ between groups in response to positive, negative, and neutral cues. It can be concluded from this study that attention manipulation affects the P300 differently in smokers and non-smokers. Smokers display a specific bias to smoking-related cues, and this bias is present during both explicit and implicit attentional processing. Overall, it can be concluded that both explicit and implicit attentional processes appear to play an important role in drug-related processing bias
APPLICATION OF NITROSOMONAS AND ANAMMOX COMBINATION IN A REACTOR FOR AMMONIUM REMOVAL IN SWINE WASTEWATER
This study investigated the combination of two kinds of autotrophic bacteria, named Anammox and Nitrosomonas in a reactor to remove ammonium existed in swine wastewater. The reactor which was operated with swine wastewater taken from Dong A pig breeding enterprise (Di An, Binh Duong) had 15 liters volume. The biomass carrier used in this model was made from the synthetic acrylic with attached capacity of 0.5-0.6g-SS/g-material. The sludge was taken from a reactor using partial nitritation/Anammox processes of a previous study at Vietnam Academy of Science and Technology. In 118 days of operation, average influent ammonium was 350mg/l, feeding to three loading rates (LR) 0.47, 0.70, 0.93 kg N-NH4+/m3/day with flow rate 20, 30, 40 liters, respectively. The highest efficiency was found at the first loading rate 0.47 kg N-NH4+/m3/day with 91.55 %. The other loading rates 0.70 and 0.93 kg N-NH4+/m3/day gave lower efficiency, 78.08 and 70.5 %, respectively. VSS at the beginning and the end of the operation were 4g/l and 9.4 g/l, respectively. The optimum pH for the reactor was in range of 7.8 - 8.0
Modelling Parametric Vibration of Gear-Pair Systems as a Tool for Aiding Gear Fault Diagnosis
The main components in gear vibration spectra are the tooth-meshing frequency and its harmonics, together with sideband structures due to modulation effects. Sideband structures can be used as an important diagnostic symptom for gear fault detection. The main objective of the present paper is to unravel amplitude modulation effects which are responsible for generating such sidebands. The parametrically excited vibration of a gear-pair system in mesh was investigated. A comparison between the model result and actual experimental data from a test rig was also presented. Some analytical expressions are derived to provide a logical explanation for ob-served phenomena. The modelling result can be used to predict sideband amplitude in presence of the distributed gear faults such as non-uniform tooth wear, pittings. It may serve as a tool for aiding the gear fault diagnosis
Flux Analysis Uncovers Key Role of Functional Redundancy in Formaldehyde Metabolism
Genome-scale analysis of predicted metabolic pathways has revealed the common occurrence of apparent redundancy for specific functional units, or metabolic modules. In many cases, mutation analysis does not resolve function, and instead, direct experimental analysis of metabolic flux under changing conditions is necessary. In order to use genome sequences to build models of cellular function, it is important to define function for such apparently redundant systems. Here we describe direct flux measurements to determine the role of redundancy in three modules involved in formaldehyde assimilation and dissimilation in a bacterium growing on methanol. A combination of deuterium and (14)C labeling was used to measure the flux through each of the branches of metabolism for growth on methanol during transitions into and out of methylotrophy. The cells were found to differentially partition formaldehyde among the three modules depending on the flux of methanol into the cell. A dynamic mathematical model demonstrated that the kinetic constants of the enzymes involved are sufficient to account for this phenomenon. We demonstrate the role of redundancy in formaldehyde metabolism and have uncovered a new paradigm for coping with toxic, high-flux metabolic intermediates: a dynamic, interconnected metabolic loop
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