<b>Serotype circulation and dengue</b>

In our study, we investigated how the circulation of different dengue virus (DENV) serotypes can influence the incidence of severe dengue and dengue with warning signs in Peru, a country where dengue is endemic. We analyzed 16 years of data from the dengue surveillance system, including nearly 58,000 serotype identification reports and 57,966 cases of severe dengue and dengue with warning signs. We found that regions with specific circulation of DENV-2, either alone or in combination with other serotypes, had higher incidence rates of severe dengue and dengue with warning signs. Our findings highlight the importance of monitoring DENV serotype circulation to manage and prevent severe dengue, especially in regions where DENV-2 is prevalent.</p

Barriers to dog rabies vaccination during an urban rabies outbreak: Qualitative findings from Arequipa, Peru - Fig 1

<p>Urban (A) and peri-urban communities (B) where FG were conducted.</p

Participant characteristics.

<p>Participant characteristics.</p

Evaluation of gravid Iquitos <i>Ae</i>. <i>aegypti</i> mortality based on bacterial bead lyophilization date.

<p>Mean percentage (± SD) mortality of gravid Iquitos strain <i>Ae</i>. <i>aegypti</i> (n = 50) exposed for 24-h to HLB second “H” trap prototype in walk-in bioassay cages. Each trap contained 500 mL of Raleigh tap water and the contents of one A&K pouch (80 mg spinosad and 100 mg bacterial beads). Dates correspond to the dates that bacterial beads were lyophilized.</p

Evaluation of trap prototype based on room placement in the walk-in room.

<p>Mean percentage (± SD) of gravid NOLA strain <i>Aedes aegypti</i> caught on sticky panels in red striped cans with black tops placed 1 m apart in the center or in corners of a walk-in room (n = 4). Percentages represent females that were trapped in the experimental trap relative to the total number of females trapped in all four traps used in each assay, i.e., the sum of all percentages for each experimental design equals 100%.</p

Evaluation of cans with stripe patterns compared to black cans.

<p>Stripe patterns on black cans evaluated in walk-in cage, sticky panel bioassays. Cans were evaluated at the same time.</p

Evaluation of trap prototype based on exposure to different light levels in walk-in bioassay cage.

<p>Mean percentage (± SD) of gravid NOLA strain <i>Ae</i>. <i>aegypti</i> caught on sticky screens in red and black cans placed in diagonal corners of walk-in bioassay cages. One corner was dimly lit while the opposite corner had normal light levels.</p

Participatory and interactive model depicting design approach.

<p>Model depicting the iterative participatory approach throughout the six phases of the trap design process.</p

Depiction of evaluation of various trap prototypes.

<p>Top panel: Walk-in bioassay room showing placement of red cover and black cover cans. Bottom panel: Black cans fitted with small, medium and large sized covers (left to right).</p

Depiction of Model P prototype.

<p>Model P prototype trap showing Duranet® netting.</p