Global Burden of Cardiovascular Diseases and Risks, 1990-2022

No description supplied</p

Additional file 1: of Hypertension management in rural western Kenya: a needs-based health workforce estimation model

Draft Excel model 20160508 BACKUP. (XLSX 677 kb

Study design and experimental protocol.

<p>Study design and experimental protocol.</p

Echocardiographic RV function and structural remodeling.

<p>D-Embo, distal embolization model; P+D-Embo, proximal + distal embolization model; EDV, end-diastolic volume; ESV, end-systolic volume; RVEF, right ventricular ejection fraction; MPI, myocardial performance index; TDI peak S, tissue Doppler imaging peak systolic myocardial velocity; TAPSE, tricuspid annular plane systolic excursion; RV, right ventricle; LV, left ventricle.</p><p>^ap<0.05 <i>post-hoc</i> comparison: Sham vs. P+D-Embo.</p><p>^bp<0.05 <i>post-hoc</i> comparison: P+D-Embo vs. D-Embo.</p><p>Echocardiographic RV function and structural remodeling.</p

Pulmonary vascular remodeling.

<p>At 8 weeks, lungs were harvested, processed, and stained with Masson’s trichrome to examine pulmonary vascular remodeling. Representative images from A) sham and B-D) embolization models with similar patterns of remodeling, including luminal encroachment and hypertrophic intimal and medial remodeling, were observed for the D-Embo (B, D) and P+D-Embo pigs (C). In selected images (D), microspheres are present in the vessel lumen. There is also extensive perivascular collagen deposition. The distal pulmonary arteries were examined in the periphery of the lung in vessels that were not occluded by beads in sections stained with hematoxylin and eosin. Representative vessels from E) sham, F) D-Embo, and G) P+D-Embo animals are shown. H) Vessel media thickness as an indicator of pulmonary artery remodeling was assessed. P+D-Embo, proximal and distal embolization group; D-Embo, distal embolization group. Scale bars for A, B, C, and D are 60 μm, 100 μm, 60 μm, and 60 μm, respectively. *p<0.05 vs. D-Embo, **p<0.01 vs. sham by ANOVA.</p

Additional file 5 of Mitral valve prolapse morphofunctional features by cardiovascular magnetic resonance: more than just a valvular disease

Additional file 5. Left ventricle peak systolic circumferential strain. Table including individual LV segments peak systolic circumferential strain measurements

Additional file 3 of Mitral valve prolapse morphofunctional features by cardiovascular magnetic resonance: more than just a valvular disease

Additional file 3. Late gadolinium enhancement in patients with mitral valve prolapse. Examples of 4 patients with MVP and typical examples of intramyocardial LGE (asterisks) in the basal inferolateral (A and B), basal inferior (C) and basal anterolateral (D) segments. An example of papillary muscle LGE is also shown in C (arrow)

Additional file 2: Figure S1. of Characterization and clinical significance of right ventricular mechanics in pulmonary hypertension evaluated with cardiovascular magnetic resonance feature tracking

Bland-Altman plots for inter-observer agreement. (PPTX 509 kb

Additional file 1 of Early insulin resistance in normoglycemic low-risk individuals is associated with subclinical atherosclerosis

Supplementary Material

Comparison between studies utilizing embolization techniques to create large animal pulmonary hypertension models.

<p>Data expressed as mean (SD) unless stated otherwise. SB: spontaneous breathing.</p><p>^a Per protocol.</p><p>^bCompared with baseline (vs. control group).</p><p>^cOnly reported in 2/5 cases.</p><p>^dIndexed (BSA).</p><p>^eMedians (IQR) reported.</p><p>NR = not reported. RHC, right heart catheterization; mPAP, mean pulmonary artery pressure; Δ mPAP, change in mean pulmonary artery pressure; PVR, pulmonary vascular resistance; Δ PVR, change in pulmonary vascular resistance; RV/(LV+S), right ventricular weight divided by left ventricular + septum weight (Fulton index); Δ RV/(LV+S), change in right ventricular weight divided by left ventricular + septum weight (Fulton index); RV, right ventricle.</p><p>Comparison between studies utilizing embolization techniques to create large animal pulmonary hypertension models.</p