Soft-sediment deformation structures in seismically affected deep-sea Miocene turbidites (Cilento Basin, southern Italy)

Soft-sediment deformation structures (SSDS) are widespread in the upper part of the S. Mauro Formation (Cilento Group, Middle-Late Miocene). The succession is represented mainly by thick and very thick, massive, coarse-grained sandstones, deposited by rapid sedimentation of high-density turbidity currents. The most common SSDS are short pillars, dishes, sedimentary sills and convolutions. They occur mostly in the upper parts of sandstone beds. Vertical tubes of 4-5 cm in diameter and up to 50 cm long constitute the most striking structures. They begin in the middle part of sandstone beds, which are basically massive or contain faint dish structures. These tubes can bifurcate upwards and/ or pass into bedding-parallel veins or dikes. The vertical tubes sometimes form sand volcanoes on the then sedimentary surface. The SSDS are interpreted as the result of earthquake-triggered liquefaction and/or fluidisation of the turbidites that were affected by the seismic shocks. This implies that the deformed layers should be considered as seismites

Mechanical ventilation in the early phase of ST elevation myocardial infarction treated with mechanical revascularization

Background: So far, few data have been available on the incidence and outcome of patients with acute myocardial infarction (MI) requiring mechanical ventilation (MV). The aim of the study was to assess the clinical and prognostic impact of MV at short and long term in 106 patients with ST elevation MI (STEMI) requiring mechanical ventilation.Results: The incidence of mechanical ventilation was 7.6%. Reasons for intubation were as follows: cardiogenic shock in 64 (60.4%) patients, ventricular fibrillation in 32 (30.1%) patients and acute pulmonary edema in 10 (9.5%) patients. Patients submitted to MV were older (p = 0.016), more frequently had a previous percutaneous coronary intervention (PCI;p = 0.014) and a previous MI (p = 0.001). A higher in-Intensive Cardiac Care Unit death was observed in MV patients (44.3% vs. 1.5%, p < 0.001), as well as a higher mortality at follow-up (36.7% vs. 14.8%, p < 0.001). MV was associated with higher mortality rates both at short and long term.Conclusions: In a large series of consecutive STEMI patients submitted to MV, the need of MV is a strong prognostic indicator of mortality both at short and long term. Among mechanically ventilated STEMI patients infarct size (as inferred by TnI values) and PCI failure were independent predictors of early death, while the duration of MV was related to death at longterm

A Virtual Reality Etruscan Museum Exhibition–Preliminary Results Of The Participants’ Experience

The current global health emergency has posed the need to reflect upon how to guarantee high standard of quality in 100% virtual exhibition. In this case study, we present one of the possible solutions to design a VR museum exhibition for educational purposes. The Centre for Museum Studies designed “The E-Trouria App”, a VR exhibition which is aimed at providing participants with personalised learning path based on an Etruscan museum collection in Rome. The App was designed by combining different pedagogical methods such as Digital Storytelling and Reflective Questioning. The goals of the research were to understand visitors' evaluation of their experience. 20 postgraduate students (F = 17; M = 3; Average age = 36 years) in Museum Education took part in the pre-pilot experimentation. Participants expressed very positive evaluation on the visit and their features (narratives, soundtrack and multimodality). Participants were emotionally engaged during the visit and the most reported emotions were “pleasure” and “wondering”. Future research steps are illustrated

Thrombus aspiration in ST-elevation myocardial infarction: Does it actually impact long-term outcome?

Background: The effect of thrombus aspiration on mortality is still controversial, with results which are often inconsistent in different randomized trials, real world registries and differ­ent follow-up duration. The aim of this analysis was to assess the effect on 30-day and 1-year mortality of thrombus aspiration during primary percutaneous coronary intervention (pPCI) for ST-elevation myocardial infarction (STEMI) compared with conventional PCI. Methods: We used data from all the consecutive STEMI patients treated either with conven­tional PCI or thrombus aspiration between January 1, 2004 and January 1, 2012. Propensity matching score was calculated on the basis of several baseline and procedural characteristics in order to predict the probability for each patient of having been treated with thrombus aspira­tion. This propensity score analysis was used in order to select a cohort of patients treated with thrombus aspiration matched one-to-one with patients treated with conventional PCI. Results: In total, 744 (53.1%) patients out of 1,400 enrolled were treated with thrombus as­piration. In the matched cohort, at 30-day follow-up 6.3% of patients in the conventional PCI group died compared to 4.7% in the thrombus aspiration group. The unadjusted hazard ratio (HR) for 30-day mortality was 1.01 (95% CI 0.33–3.14, p = 0.985). In the same cohort, 10.7% of patients died at 1-year in the conventional PCI group compared to 5.2% in the thrombus as­piration group. The 1-year unadjusted hazard ratio for mortality was 0.47 (95% CI 0.25–0.90, p = 0.025). The HR changed and was no longer significant after adjustment for differences in the use of glycoprotein (GP) IIb/IIIa inhibitors, lesion pre-dilatation and pre-procedural TIMI flow: 0.71 (95% CI 0.36–1.39, p = 0.322). Conclusions: Thrombus aspiration does not influence 30-day mortality, however it is associated with 1-year survival benefit. GP IIb/IIIa inhibitors and thrombus aspiration may have an important synergistic role in leading to this long-term benefit