Prevalence and severity of freezing of gait in a Danish cohort of people with Parkinsonʼs disease

\ua9 2023, Almindelige Danske Laegeforening. All rights reserved.INTRODUCTION. Parkinson’s disease (PD) is a widespread neurodegenerative disorder characterised by wide range of symptoms. Freezing of gait (FoG), a transient feeling that the patient’s feet are nailed to the floor, resulting in an inability to move, is a particularly distressful symptom. The assessment of FoG can be challenging. Often, clinicians are reliant on patients’ subjective experiences and patient questionnaires such as the Freezing of Gait Questionnaire (FOGQ) and its updated version, the New FOGQ (NFOGQ).Until now, the NFOGQ has not been validated and piloted for use in Danish. Therefore, few attempts have been made to assess the prevalence and severity of FoG in Danish patients with PD. METHODS. This report describes a two-step process of adapting the NFOGQ into Danish and piloting its use among a cohort of patients with PD. A satisfactory translation (Danish NFOGQ) was produced and successfully piloted. RESULTS. The translation showed robust test-retest reliability after two weeks. Patients fully understood the questionnaire. Using the Danish NFOGQ in an online prevalence survey, we found that 35.7% of respondents had experienced FoG and that the prevalence correlated with disease duration. CONCLUSION. The Danish NFOGQ appears to be appropriate for assessing FoG in Danish patients with PD in both clinical and research settings

Reproductive, dispersal and recruitment strategies in Australian seagrasses

Seagrasses are a relatively small group of marine angiosperms that have successfully colonised the oceans and includes monecious, dioecious and hermaphroditic species. They display a range of mating systems, dispersal mechanisms and recruitment strategies that have allowed them to adapt and survive within the marine environment. This includes a general reduction in the size and complexity of floral structures, and subsurface pollination (hydrophily) in the majority of species. Fertilisation occurs through water-dispersed pollen that is typically filamentous and sticky, however, recent work has also suggested that marine invertebrates may play a role in pollen movement and fertilisation. Seed size and morphology varies widely among species, from fleshy floating fruit (e.g. Posidonia) to small negatively buoyant seeds less than 0.5 mm (e.g. Halophila). Nearly all species retain some capacity of asexual reproduction through rhizome elongation or the production of asexual fragment or propagules that can be more widely dispersed. These differences in reproductive strategies have important effects on recruitment and dispersal potential and subsequent population dynamics. Direct estimates of dispersal and recruitment are inherently difficult to assess in seagrasses, but the use of novel genetic and predictive modelling approaches are providing new insights into these important processes. This chapter highlights the main reproductive strategies and adaptations seagrass have undergone in response to reproducing in a marine environment, with an emphasis on Australian seagrass species. We highlight the current state of knowledge in Australian seagrass reproductive biology and future directions in seagrass reproductive biology research