576 research outputs found

    Caracterização e tratamento do efluente de uma estação de serviço

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    O presente estudo incidiu na caracterização e tratamento das lamas retidas nos separadores de hidrocarbonetos instalados numa estação de serviço. Recorreu-se à técnica de respirometria para obter informação prévia sobre a toxicidade e a tratabilidade das lamas por um Sequencial Batch Biofilm Reactor (SBBR). Utilizou-se um inóculo de lamas activadas e uma cultura de Pseudomonas putida. Os testes respirométricos permitiram avaliar a capacidade destas culturas crescerem num meio contendo hidrocarbonetos como única fonte de carbono e verificar o efeito de diferentes concentrações de substrato na actividade microbiana.Instituto de Biotecnologia e Química Fina (IBQF); programa PRAXIS

    Reação de linhagens de feijoeiro de oito ciclos de seleção recorrente visando a resistência à Pseudocercospora griseola a dois isolados do patógeno.

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    A mancha angular incitada pelo fungo Pseudocercospora griseola é um dos principais problemas da cultura do feijoeiro em algumas regiões do Brasil. Visando a obter linhagens resistentes a esse patógeno, um programa de seleção recorrente vem sendo conduzido há alguns anos pela Universidade Federal de Lavras (UFLA) e Embrapa Arroz e Feijão. Esse trabalho visa avaliar o desempenho de linhagens obtidas nos diferentes ciclos seletivos, sob condições de casa de vegetação, com relação a dois isolados de P griseola

    The χc1(4274)\chi_{c1}(4274) multiplicity in heavy-ion collisions

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    In a previous work we computed the thermally-averaged cross sections for the production and absorption of the χc1(4274)\chi_{c1}(4274) state in the hot hadron gas formed in heavy ion collisions. In the present work we estimate the final yield of this exotic state in these collisions. We use the coalescence model to fix the initial multiplicities. The state is is treated as a P−P-wave bound state of DsDˉs0D_s\bar D_{s0} and also as a compact tetraquark. The Bjorken picture is used to model the hydrodynamic expansion and cooling. Then, the kinetic equation is solved to evaluate the time evolution of the χc1(4274)\chi_{c1}(4274) yield during the hot hadron gas phase. Since the χc1(4274)\chi_{c1}(4274) decay width is large it might decay inside the hadron gas. Therefore we also include the chic1(4274)chi_{c1}(4274) decay and regeneration terms by means of an effective coupling, estimated from the available data. The combined effects of hadronic interactions and the χc1(4274)\chi_{c1}(4274) decay have a strong impact on the final yield. Also, predictions of the χc1(4274)\chi_{c1}(4274) multiplicity as a function of centrality and of the charged hadron multiplicity (measured at midrapidity) are presented. Finally, we calculate the yield of a proposed P−P-wave molecular state of DsDs0ˉD_s \bar{D_{s0}}, Y′(4274)Y^{\prime}(4274), characterized by a smaller width and smaller coupling constant obtained from the Weinberg compositeness condition.Comment: 7 pages, 5 figure

    Dynamic aspects of oral processing of curcumin-loaded solid lipid nanoparticles yoghurts by rheology and soft tribology assessment

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    Mouthfeel and consistency originating from the consumption of yoghurts represent decisive factors for the consumers’ acceptability. The present work aims to identify potential differences in the sensory perceptions of yoghurts with curcumin-loaded solid lipid nanoparticles (SLN) incorporation. Thus, rheology coupled with tribology were considered to simulate the dynamic aspects of oral processing. Similar values for the elastic (G’) and viscous (G’’) parameters were obtained for both control yoghurt and yoghurt with curcuminloaded SLN, as well as flow index (n) and consistency index (k) around 0.56 and 1.50 Pa.sn, respectively. However, the friction behaviour was characterised by significant differences in all tribological regimes, suggesting that the incorporation of nanoparticles in yoghurts could potentially affect the after-feel upon swallowing, whilst not directly impacting on yoghurt’s structure

    High-grade atrioventricular block in ST-segment elevation myocardial infarction patients: insights of a terciary centre

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    Background: High-grade atrioventricular block (HABV) is associated with poorer outcomes in the setting of acute coronary syndromes. Limited information is available on the incidence and death associated with HABV in STEMI patients (pts) receiving contemporary treatment. Aim: To evaluate the incidence of HABV and its impact on outcome of STEMI patients, in primary percutaneous coronary intervention era. Methods: We analysed retrospectively 1149 STEMI pts admitted, consecutively, in our coronary care unit, from July of 2009 to June 2014. They were divided in two groups: group 1 – pts without HABV, n=1057, 92%); group 2 – pts with HABV (n=92, 8%). For each group we compared clinical features and adverse events. Primary endpoint was the occurrence of death at 6 months; follow-up was completed in 99,8% of patients. Results: Patients of group 2 were older (62±13 vs 69±15;p1 (18.0 % vs 42.4%;p1 (71.4% vs 37,2%;p<0.001), left ventricular dysfunction (100% vs 34.8%;p<0.001), but less right ventricular dysfunction (7.1% vs 28.4%;p<0.001). Compared with IMI pts, AMI pts had higher risk of in hospital [OR 9.04, 95% CI (2.87-28.50);p<0.001] and 6-month mortality [OR 10.88; 95% CI (3.33 – 35.53);p<0.001]. After adjusting for different baseline characteristics in multivariate analysis, HABV patients had higher risk of overall 6-month mortality compared to those without HABV [OR 2.18, 95% CI (1.25-3.79),p=0.006]. Conclusion: Besides low incidence of HABV, this complication continues to have a high risk of in-hospital and 6-month mortality and occurring with AMI the risk increases significantly

    Cardiogenic shock complicating acute coronary syndromes

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    INTRODUCTION: Despite advances in the treatment of patients with acute coronary syndromes (ACS), cardiogenic shock (CS) remains the leading cause of death in these patients. PURPOSE: Determine characteristics and management of patients with an ACS complicated by CS. Determine predictors of development of CS during hospitalization and predictors of in-hospital mortality. METHODS: Retrospective study of 2064 patients consecutively admitted for ACS in a Coronary Unit over a period of 4 years. RESULTS: During the years under study, 111 patients (5.4%) developed CS. Patients with CS were more likely to be older (69.8 ± 13.2 vs 63.5 ± 13.1 years, p<0.001); there were no significant differences in other clinical characteristics. Myocardial Infarction with ST segment elevation (STEMI) was more frequent in patients with CS (p<0.001). Patients with CS underwent less often coronary angiography (p<0.001), revascularization (p = 0.004) and were less treated with β-blocker (p <0.001) and ACE inhibitors therapy (p <0.001). In multivariate analysis, predictors of occurrence of CS during hospitalization were: tachycardia (OR 3.2, 95% CI 1.6-6.3), systolic blood pressure 1 (OR 3.5, 95% CI 1.8-6.8) at admission. The in-hospital mortality of patients with CS was 45%, compared with 1.7% in those who did not develop CS. Factors associated with an increased mortality in patients with CS included absence of coronary revascularization (OR 4.9, 95% CI 1.5-16.0), GFR <60ml/min (OR 4.4, 95% CI 1.3-15.6), advanced age (OR 6.4, 95% CI 1.6-26.2) and LVEF ≤ 35 % (OR 3.9, 95% CI 1.3-12.4). CONCLUSION: According to the literature, our review showed that CS in the context of ACS is associated with a high mortality. We identified clinical markers that are associated with the development of CS and may spot patients at risk earlier. Absence of coronary revascularization remains an independent predictor of mortality in CS

    Temporal trends of risk profile among patients admitted with acute coronary syndrome

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    Background: Clinical practice focuses on the primary prevention of cardiovascular (CVD) disease through the modification and pharmacological treatment of elevated risk factors, in order to minimize long-term CVD risk. Aim: To determine if there are differences in risk profile of patients admitted with acute coronary syndrome over time. Methods: We analysed 4871 patients admitted consecutively in our coronary care unit with a diagnosis of ACS and included in a prospective registry, from January 2002 to October 2013. Patients were divided in 3 groups of 4 consecutive years: group 1 – from 2002 to 2005 (n=1245, 25.6%); group 2 – from 2006 to 2009 (n=1562, 32%); group 3 - from 2010 to 2013 (n=2064, 42.4%). For each group we studied the prevalence of conventional risk factors (CRF) including diabetes, hypertension, smoking and dyslipidaemia over time and compared findings according to sex and type of acute coronary syndrome: Results: Women were less prevalent in group 3 (26.2% vs 26.9% vs 22.6%, p=0.006). Temporal trends of age and diabetes didn’t show statistic signify. Group 2 and 3 evidenced higher body mass index (26.48±4.0 vs 27.13±5.8 vs 27.15±4.67 kg/m2; p<0.001), had higher prevalence of dyslipidaemia (43.1% vs 49.2% vs 56.3%; p<0.001), smoking (39.4% vs 65.0% vs 64.4%; p<0.001) and hypertension (55.7% vs 65.0% vs 64.4%; p<0.001). We found at least 1 CRF in 92,4% of patients. The first temporal period had higher prevalence of 1 or 2 CRF, on the contrary two thirds of patients in group 3 had 2 or 3 CRF. Over time, hypertension was more prevalent in women (69.3% vs 77,4% vs 78.6%; p=0,007), on the other hand, smoking and dyslipidaemia occurred more often in men. It was observed an increasing tendency of smoking (44% vs 41.6% vs 54%; p100 mg/dl more often (66% vs 57% vs 68.8%; p=0.022), but higher control of systolic blood pressure below 140mmHg (54.2% vs 59.6% vs 65.7%, p<0.001. Conclusion: We found that the risk profile of patients presenting with acute coronary syndrome worsened over the years. In recent time, patients had more CRF, being smoking and hypertension the leaders
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