12 research outputs found

    La protection des mineurs dans le secteur de l'audiovisuel : une déclaration d'intention ou un véritable objectif législatif ?

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    Master [120] en droit, Université catholique de Louvain, 201

    Indicateurs de stress chez les grands singes africains

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    info:eu-repo/semantics/publishe

    Prototyping Novel Instruments for Fetal Surgery through Virtual Reality Simulation and 3D Printing

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    Designing novel medical devices is a complex matter. Involving clinicians as early as possible into the development process is of crucial importance; it helps to shorten the development cycle and increases the likelihood of later acceptance by clinicians. In this paper we show how through a combination of 3D printing and Virtual Reality simulation it is possible to involve clinicians in a very early stage, yet receive concrete quantitative and qualitative information that can shift the design to a more appropriate line of thought. Treatment of the Twin-toTwin Transfusion Syndrome serves as a case study for this work. At present rigid endoscopes are used to direct a laser to treat the twin’s placenta. We study here whether flexible endoscopes would be more appropriate. More in particular, we investigate whether one or two distal bending degrees of freedom would be advantageous and how they are to be handled by the surgeon. Preliminary experiments show a preference for a single distal bending degree of freedom, but without conclusive statistical evidence. From the results guidelines for future experiments have been derived.status: publishe

    Effects of Cyclic Fatty Acid Monomers from Heated Vegetable Oil on Markers of Inflammation and Oxidative Stress in Male Wistar Rats

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    International audienceThis study assesses the effects of cyclic fatty acid monomers (CFAM) from heated vegetable oils on oxidative stress and inflammation. Wistar rats were fed either of these four diets for 28 days: canola oil (CO), canola oil and 0.5% CFAM (CC), soybean oil (SO), and soybean oil and 0.5% CFAM (SC). Markers of oxidative stress and inflammation were determined by micro liquid chromatography tandem mass spectrometry (micro-LC-MS/MS) and enzyme-linked immunosorbent assay (ELISA) kits, respectively. Analysis of variance (ANOVA) for a 2 × 2 factorial design was performed to determine the CFAM and oil effects and interactions between these two factors at P ≤ 0.05. For significant interactions, a post hoc multiple comparison test was performed, i.e., Tukey HSD (honest significant difference) test. CFAM induced higher plasma levels of 15-F2t-IsoP (CC, 396 ± 43 ng/mL, SC, 465 ± 75 ng/mL vs CO, 261 ± 23 ng/mL and SO, 288 ± 35 ng/mL, P < 0.05). Rats fed the SC diet had higher plasma 2,3-dinor-15-F2t-IsoP (SC, 145 ± 9 ng/mL vs CC, 84 ± 8 ng/mL, CO, 12 ± 1 ng/mL, and SO, 12 ± 1 ng/mL, P < 0.05), urinary 2,3-dinor-15-F2t-IsoP (SC, 117 ± 12 ng/mL vs CC, 67 ± 13 ng/mL, CO, 15 ± 2 ng/mL, and SO, 18 ± 4 ng/mL, P < 0.05), and plasma IL-6 (SC, 57 ± 10 pg/mL vs CC, 48 ± 11 pg/mL, CO, 46 ± 9 pg/mL, and SO, 44 ± 4 pg/mL, P < 0.05) than the other three diet groups. These results indicate that CFAM increased the levels of markers of oxidative stress, and those effects are exacerbated by a CFAM-high-linoleic acid diet
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