106 research outputs found

    Analysis of E-Learning Concept

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    E-Learning plays vital role in recent years. It is defined as learning with a computer where you can learn in a learning environment and also connected with your teacher. Mostly an e-Learning is a self study course with self interest. In this paper we discuss the overview of e-learning that is history of e-learning, its four main components such as standardization of content, development of content, management of content, and delivery of content with examples, authoring tools and the types of content to present the concept in interactive way

    Spectroscopic (FT-IR, FT-Raman and NMR) and NBO analysis of 3, 4-dimethylanisole by density functional method

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    Combined experimental and theoretical studies have been conducted on the molecular structure and vibrational, spectra of 3, 4-dimethyl anisole (DMA). The FT-IR and FT-Raman spectra of DMA have been recorded in the solid phase. The molecular geometry and vibrational frequencies of DMA in the ground state have been calculated by using the ab-initio Hartree-Fock (HF) and density functional methods (B3LYP) invoking 6-31+G (d,p) basis set. The optimized geometric bond lengths and bond angles obtained by HF method shows best agreement with the experimental values. Comparison of the observed fundamental vibrational frequencies of DMA with calculated results by HF and density functional methods indicates that B3LYP is superior to the scaled HF approach for molecular vibrational problems. The difference between the observed and scaled wave number values of most of the fundamental is very small. The thermodynamic functions and atomic change of the title compound has also been performed at HF/B3LYP/6-31+G(d,p) level of theories. A detailed interpretation of the FT-IR, FT-Raman, NMR spectra of DMA has also been reported. The theoretical spectrograms for infrared and Raman spectra of the title molecule have been constructed. The thermodynamic function of the title compound has also been performed at HF/6-31+G (d,p) and B3LYP/6-31+G (d,p) level of theories. Natural bond orbital analysis has been carried out to explain the change transfer or delocalization of change due to the intra-molecular interactions. Energy of the highest occupied molecular (HOMO) orbital and lowest unoccupied (LUMO) molecular orbital have been predicted

    EFFECT OF CONVEX DIE ANGLE OF PORTHOLE DIE ON PLASTIC DEFORMATION AND EXTRUSION PROCESS IN TUBE EXTRUSION

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    ABSTRACT Port hole die extrusion has a great advantage in the forming of hollow section tubes that are difficult to produce by conventional extrusion with a mandrel on the stem. Because of the complicated structure of the die assembly, the extrusion of hollow section tubes has been investigated experimentally. During the hot extrusion of aluminum alloy 6061, the change of process parameters will affect the mechanical properties of extruded products. In this study, Taguchi method is applied to optimize the process parameters in hot extrusion of Al 6061 tubes under extrusion ratio of 24.03. The experiments are arranged by orthogonal array method in which Die with three channels and four channels are used as outer arrays, the factors selected as inner arrays are the billet heating temperature, the convex die angle, bearing length and the container temperature. The extrusions are subsequently tested for tensile test, flattening test, expanding test using a conical punch, surface finish and micro-structure. Test results are analyzed by the quality measurement of Taguchi method to find the relationship between the design process parameters and mechanical properties of the products and to acquire the optimal combination of parameter. Then based on the results obtained from the additive model, conformity experiments are performed

    A Protein-Interaction Array Inside a Living Cell

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    Protein-interaction arrays were generated in living cells by the interaction of bait-presenting artificial receptor constructs (bait-PARCs) with micrometer-scaled antibody surface patterns (see figure). This method was applied to simultaneously monitor the interaction kinetics of a prey protein with two distinct bait proteins in individual living cells

    Fabrication of polycaprolactone/β-tricalciumphosphate based nano scaffolds using electrospinning method for biomedical applications

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    1292-1297In this study, we have focused on preparation, fabrication and characterization of polycaprolactone and beta tricalcium phosphate (PCL/β-TCP) composite scaffolds that are used for bone tissue engineering applications. The electrospun composites have been characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM). The developed scaffolds are effectively simulated the morphology, mechanical property and bioactivity for load-bearing tissue engineering applications. The bioactivity of the scaffolds has been evaluated with in vitro cell adhesion and growth studies. The results confirm the nontoxic behaviour of the composite biomaterials and developed scaffolds with MG-63 osteoblast-like cell line. The synthesized scaffolds have shown promising bioactivity with the growth as well as proliferation of new bone cells with considerable osteoconductive properties. The nanoscaffolds possess better physical properties and support high cell adhesion suggesting their application in bone tissue engineering field

    Fabrication of polycaprolactone/β-tricalciumphosphate based nano scaffolds using electrospinning method for biomedical applications

    Get PDF
    In this study, we have focused on preparation, fabrication and characterization of polycaprolactone and beta tricalcium phosphate (PCL/β-TCP) composite scaffolds that are used for bone tissue engineering applications. The electrospun composites have been characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM). The developed scaffolds are effectively simulated the morphology, mechanical property and bioactivity for load-bearing tissue engineering applications. The bioactivity of the scaffolds has been evaluated with in vitro cell adhesion and growth studies. The results confirm the nontoxic behaviour of the composite biomaterials and developed scaffolds with MG-63 osteoblast-like cell line. The synthesized scaffolds have shown promising bioactivity with the growth as well as proliferation of new bone cells with considerable osteoconductive properties. The nanoscaffolds possess better physical properties and support high cell adhesion suggesting their application in bone tissue engineering field
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