12 research outputs found
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-Gómez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- Antón Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- Araújo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
- Baek A
- Baek S-H
- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
- Ballester M
- Balzan R
- Bandopadhyay R
- Banerjee S
- Banerjee S
- Bao Y
- Baptista MS
- Baracca A
- Barbati C
- Bargiela A
- Barilà D
- Barlow PG
- Barmada SJ
- Barreiro E
- Barreto GE
- Bartek J
- Bartel B
- Bartolome A
- Barve GR
- Basagoudanavar SH
- Bassham DC
- Bast RC
- Basu A
- Batoko H
- Batten I
- Baulieu EE
- Baumgarner BL
- Bayry J
- Beale R
- Beau I
- Beaumatin F
- Bechara LRG
- Beck GR
- Beers MF
- Begun J
- Behl C
- Behrends C
- Behrens GMN
- Bei R
- Bejarano E
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- Belgareh-Touzé N
- Bellarosa C
- Belleudi F
- Bello-Morales R
- Belló Pérez M
- Beltran JSDO
- Beltran S
- Benbrook DM
- Bendorius M
- Benitez BA
- Benito-Cuesta I
- Bensalem J
- Berchtold MW
- Berezowska S
- Bergamaschi D
- Bergami M
- Bergmann A
- Berliocchi L
- Berlioz-Torrent C
- Bernard A
- Berthoux L
- Besirli CG
- Besteiro S
- Betin VM
- Beyaert R
- Bezbradica JS
- Bhaskar K
- Bhatia-Kissova I
- Bhattacharya R
- Bhattacharya S
- Bhattacharyya S
- Bhuiyan MS
- Bhutia SK
- Bi L
- Bi X
- Biden TJ
- Bijian K
- Billes VA
- Binart N
- Bincoletto C
- Birgisdottir AB
- Bjorkoy G
- Blanco G
- Blas-Garcia A
- Blasiak J
- Blomgran R
- Blomgren K
- Blum JS
- Boada-Romero E
- Boban M
- Boesze-Battaglia K
- Boeuf P
- Boland B
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- Bonaldo P
- Bonam SR
- Bonfili L
- Bonifacino JS
- Boone BA
- Bootman MD
- Bordi M
- Borner C
- Bornhauser BC
- Borthakur G
- Bosch J
- Bose S
- Botana LM
- Botas J
- Boulanger CM
- Boulton ME
- Bourdenx M
- Bourgeois B
- Bourke NM
- Bousquet G
- Boya P
- Bozhkov PV
- Bozi LHM
- Bozkurt TO
- Brackney DE
- Brand-Saberi B
- Brandts CH
- Braun RJ
- Braus GH
- Bravo-Sagua R
- Bravo-San Pedro JM
- Brest P
- Bringer M-A
- Briones-Herrera A
- Broaddus VC
- Brodersen P
- Brodsky JL
- Brody SL
- Bronson PG
- Bronstein JM
- Brown CN
- Brown RE
- Brum PC
- Brumell JH
- Brunetti-Pierri N
- Bruno D
- Bryson-Richardson RJ
- Bucci C
- Buch S
- Buchan JR
- Buchrieser C
- Buckingham EM
- Budak H
- Budini M
- Bueno M
- Buitrago-Molina LE
- Bultynck G
- Burada F
- Buraschi S
- Burgoyne JR
- Burón MI
- Bustos V
- Butturini E
- Byrd A
- Bánréti Á
- Büttner S
- Cabas I
- Cabrera-Benitez S
- Cadwell K
- Cai J
- Cai L
- Cai Q
- Cairó M
- Calbet JA
- Caldwell GA
- Caldwell KA
- Call JA
- Calvani R
- Calvo AC
- Calvo-Rubio Barrera M
- Camara NO
- Camonis JH
- Camougrand N
- Campanella M
- Campbell EM
- Campbell-Valois F-X
- Campello S
- Campesi I
- Campos JC
- Camuzard O
- Cancino J
- Candido de Almeida D
- Canesi L
- Caniggia I
- Canonico B
- Cantí C
- Cao B
- Caraglia M
- Caramés B
- Carchman EH
- Cardenal-Muñoz E
- Cardenas C
- Cardenas L
- Cardoso SM
- Carew JS
- Carle GF
- Carleton G
- Carloni S
- Carmona-Gutierrez D
- Carneiro LA
- Carnevali O
- Carosi JM
- Carra S
- Carrier A
- Carrier L
- Carroll B
- Carter AB
- Carvalho AN
- Casanova M
- Casas C
- Casas J
- Cassioli C
- Castillo EF
- Castillo K
- Castillo-Lluva S
- Castoldi F
- Castori M
- Castro AF
- Castro-Caldas M
- Castro-Hernandez J
- Castro-Obregon S
- Catz SD
- Cavadas C
- Cavaliere F
- Cavallini G
- Cavinato M
- Cayuela ML
- Cebollada Rica P
- Cecarini V
- Cecconi F
- Cechowska-Pasko M
- Cenci S
- Ceperuelo-Mallafré V
- Cerqueira JJ
- Cerutti JM
- Cervia D
- Cetintas VB
- Cetrullo S
- Chae H-J
- Chagin AS
- Chai C-Y
- Chakrabarti G
- Chakrabarti O
- Chakraborty T
- Chakraborty T
- Chami M
- Chamilos G
- Chan DW
- Chan ED
- Chan EYW
- Chan H
- Chan HH
- Chan HYE
- Chan MTV
- Chan YS
- Chandra PK
- Chang C
- Chang C-P
- Chang H-C
- Chang K
- Chao J
- Chapman T
- Charlet-Berguerand N
- Chatterjee S
- Chaube SK
- Chaudhary A
- Chauhan S
- Chaum E
- Checler F
- Cheetham ME
- Chen C-S
- Chen G-C
- Chen J-F
- Chen L
- Chen L
- Chen LL
- Chen M
- Chen M-K
- Chen N
- Chen Q
- Chen R-H
- Chen S
- Chen W
- Chen W
- Chen X
- Chen X-M
- Chen X-W
- Chen Y
- Chen Y
- Chen Y
- Chen Y-G
- Chen Y-J
- Chen Y-Q
- Chen Z
- Chen Z
- Chen Z
- Chen Z-H
- Chen ZJ
- Chen ZS
- Cheng H
- Cheng J
- Cheng S-Y
- Cheng W
- Cheng X
- Cheng X-T
- Cheng Y
- Cheng Z
- Cheong H
- Cheong JK
- Chernyak BV
- Cherry S
- Cheung CFR
- Cheung CHA
- Cheung K-H
- Chevet E
- Chi RJ
- Chiang AKS
- Chiaradonna F
- Chiarelli R
- Chiariello M
- Chica N
- Chiocca S
- Chiong M
- Chiou S-H
- Chiramel AI
- Chiurchiù V
- Cho D-H
- Choe S-K
- Choi AMK
- Choi ME
- Choudhury KR
- Chow NS
- Chu CT
- Chua JJE
- Chua JP
- Chung H
- Chung KP
- Chung S
- Chung S-H
- Chung Y-L
- Cianfanelli V
- Ciechomska IA
- Cifuentes M
- Cinque L
- Cirak S
- Cirone M
- Clague MJ
- Clarke R
- Clementi E
- Coccia EM
- Codogno P
- Cohen E
- Cohen MM
- Colasanti T
- Colasuonno F
- Colbert RA
- Colell A
- Coll NS
- Collins MO
- Colombo MI
- Colón-Ramos DA
- Combaret L
- Comincini S
- Cominetti MR
- Consiglio A
- Conte A
- Conti F
- Contu VR
- Cookson MR
- Coombs KM
- Coppens I
- Corasaniti MT
- Cordes N
- Corkery DP
- Cortese K
- Costa MDC
- Costantino S
- Costelli P
- Coto-Montes A
- Crack PJ
- Crespo JL
- Criollo A
- Crippa V
- Cristofani R
- Csizmadia T
- Cuadrado A
- Cui B
- Cui J
- Cui Y
- Cui Y
- Culetto E
- Cumino AC
- Cybulsky AV
- Czaja MJ
- Czuczwar SJ
- D'Adamo S
- D'Amelio M
- D'Arcangelo D
- D'Lugos AC
- D'Orazi G
- da Silva JA
- Dafsari HS
- Dagda RK
- Dagdas Y
- Daglia M
- Dai X
- Dai Y
- Dai Y
- Dal Col J
- Dalhaimer P
- Dalla Valle L
- Dallenga T
- Dalmasso G
- Damme M
- Dando I
- Dantuma NP
- Darling AL
- Das H
- Dasarathy S
- Dasari SK
- Dash S
- Daumke O
- Dauphinee AN
- Davies JS
- Davis RJ
- Davis T
- Dayalan Naidu S
- De Amicis F
- De Bosscher K
- De Felice F
- De Franceschi L
- De Leonibus C
- de Mattos Barbosa MG
- De Meyer GRY
- De Milito A
- De Nunzio C
- De Palma C
- De Santi M
- De Virgilio C
- De Zio D
- Debnath J
- DeBosch BJ
- Decuypere J-P
- Deehan MA
- Deflorian G
- DeGregori J
- Dehay B
- Del Rio G
- Delaney JR
- Delbridge LMD
- Delorme-Axford E
- Delpino MV
- Demarchi F
- Dembitz V
- Demers ND
- Deng H
- Deng Z
- Dengjel J
- Dent P
- Denton D
- DePamphilis ML
- Der CJ
- Deretic V
- Descoteaux A
- Devis L
- Devkota S
- Devuyst O
- Dewson G
- Dharmasivam M
- Dhiman R
- di Bernardo D
- Di Cristina M
- Di Domenico F
- Di Fazio P
- Di Fonzo A
- Di Guardo G
- Di Guglielmo GM
- Di Leo L
- Di Malta C
- Di Nardo A
- Di Rienzo M
- Di Sano F
- Diallinas G
- Diao J
- Diaz-Araya G
- Dickinson JM
- Diederich M
- Dieudé M
- Dikic I
- Ding S
- Ding W-X
- Dini L
- Dinic M
- Dinić J
- Dinkova-Kostova AT
- Dionne MS
- Distler JHW
- Diwan A
- Dixon IMC
- Djavaheri-Mergny M
- Dobrinski I
- Dobrovinskaya O
- Dobrowolski R
- Dobson RCJ
- Dokmeci Emre S
- Donadelli M
- Dong B
- Dong X
- Dong XC
- Dong Z
- Dorn Ii GW
- Dotsch V
- Dou H
- Dou J
- Dowaidar M
- Dridi S
- Drucker L
- du Toit A
- Du A
- Du C
- Du G
- Du H-N
- Du L-L
- Duan S-B
- Duan X
- Duarte SP
- Dubrovska A
- Dunlop EA
- Dupont N
- Durán RV
- Dwarakanath BS
- Dyshlovoy SA
- Dávila VA
- Díaz-Laviada I
- Ebrahimi-Fakhari D
- Eckhart L
- Edelstein CL
- Efferth T
- Eftekharpour E
- Eichinger L
- Eid N
- Eisenberg T
- Eissa NT
- Eissa S
- Ejarque M
- El Andaloussi A
- El-Hage N
- El-Naggar S
- El-Shafey ES
- Eleuteri AM
- Elgendy M
- Eliopoulos AG
- Elizalde MM
- Elks PM
- Elsasser H-P
- Elsherbiny ES
- Emerling BM
- Emre NCT
- Eng CH
- Engedal N
- Engelbrecht A-M
- Engelsen AST
- Enserink JM
- Escalante R
- Esclatine A
- Escobar-Henriques M
- Eskelinen E-L
- Espert L
- Eusebio M-O
- Fabrias G
- Fabrizi C
- Facchiano A
- Facchiano F
- Fadeel B
- Fader C
- Faesen AC
- Fairlie WD
- Falcó A
- Falkenburger BH
- Fan D
- Fan J
- Fan Y
- Fang EF
- Fang Y
- Fang Y
- Fanto M
- Farfel-Becker T
- Faure M
- Fazeli G
- Fedele AO
- Feldman AM
- Feng D
- Feng J
- Feng L
- Feng W
- Feng Y
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- Fenz Araujo T
- Ferguson TA
- Fernandez-Checa JC
- Fernie AR
- Fernández ÁF
- Fernández-Veledo S
- Ferrante AW
- Ferraresi A
- Ferrari MF
- Ferreira JCB
- Ferro-Novick S
- Figueras A
- Filadi R
- Filigheddu N
- Filippi-Chiela E
- Filomeni G
- Fimia GM
- Fineschi V
- Finetti F
- Finkbeiner S
- Fisher EA
- Fisher PB
- Flamigni F
- Fliesler SJ
- Flo TH
- Florance I
- Florey O
- Florio T
- Fodor E
- Follo C
- Fon EA
- Forlino A
- Fornai F
- Fortini P
- Fracassi A
- Fraldi A
- Franco B
- Franco R
- Franconi F
- Frankel LB
- Friedman SL
- Fröhlich LF
- Frühbeck G
- Fuentes JM
- Fujiki Y
- Fujita N
- Fujiwara Y
- Fukuda M
- Fulda S
- Furic L
- Furuya N
- Fusco C
- Gack MU
- Gaffke L
- Galadari S
- Galasso A
- Galindo MF
- Gallolu Kankanamalage S
- Galluzzi L
- Galy V
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- Gan B
- Ganley IG
- Gao F
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- Gao S-J
- Gao W
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- Garcera A
- Garcia MN
- Garcia VE
- Garcia-Escudero V
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- Garcia-Macia M
- Garcia-Ruiz C
- García-Del Portillo F
- García-Moreno D
- García-Sanz P
- Garg AD
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- Garofalo T
- Garry RF
- Gassen NC
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- Geiss-Friedlander R
- Gelfi C
- Genschik P
- Gentle IE
- Gerbino V
- Gerhardt C
- Germain K
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- Gewirtz DA
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- Giampietri C
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- Gluschko A
- Goder V
- Goginashvili A
- Golab J
- Goldstone DC
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- Gomes LR
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- Gong Q
- Goni FM
- Gonzalez-Hernandez T
- Gonzalez-Polo RA
- Gonzalez-Reyes JA
- González-Gallego J
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- Goping IS
- Gorbatyuk MS
- Gorbunov NV
- Gorojod RM
- Gorski SM
- Goruppi S
- Gotor C
- Gottlieb RA
- Gozes I
- Gozuacik D
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- Granatiero V
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- Grinstaff MW
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- Grose C
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- Grune T
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- Gu X
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- Guardia CM
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- Gukovsky I
- Gunst J
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- Gustafsson AB
- Gutterman DD
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- Hariharan N
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- Hasima Nagoor N
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- Hays TS
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- Ho WY
- Hobbs GA
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- Hoet PHM
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- Hofman P
- Holmberg CI
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- Hooper LV
- Hoppe T
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- Hoshida Y
- Hsin I-L
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- Hu B
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- Hu Y-C
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- Hua F
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- Huber TB
- Hubert V
- Hubner CA
- Hughes SM
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- Humbert M
- Hummer G
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- Hussain S
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- Hussey PJ
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- Hyung-Ryong Kim
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- Iozzo RV
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- Izquierdo JM
- Izumi M
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- Ji J
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- Jiang X
- Jiang Y
- Jimenez-Sanchez M
- Jin E-J
- Jin F
- Jin H
- Jin L
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- Jin M
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- Jo E-K
- Joffre C
- Johansen T
- Johnson GVW
- Johnston SA
- Jokitalo E
- Jolly MK
- Joosten LAB
- Jordan J
- Joseph B
- Ju D
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- Judith D
- Juhász G
- Jun Y
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- Jungbluth H
- Jungverdorben J
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- Kaasik A
- Kabuta T
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- Kaludercic N
- Kalvari I
- Kaminska J
- Kaminskyy VO
- Kanamori H
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- Kang C
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- Kanki T
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- Kanthasamy A
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- Kantorow M
- Kapuy O
- Karamouzis MV
- Karim MR
- Karmakar P
- Katare RG
- Kato M
- Kaufmann SHE
- Kauppinen A
- Kaushal GP
- Kaushik S
- Kawasaki K
- Kazan K
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- Keating DJ
- Keber U
- Kehrl JH
- Keller CW
- Keller KE
- Kemper JK
- Kenchappa CS
- Kenific CM
- Kepp O
- Kermorgant S
- Kern A
- Ketteler R
- Keulers TG
- Khalfin B
- Khalil H
- Khambu B
- Khan SY
- Khandelwal VKM
- Khandia R
- Kho W
- Khobrekar NV
- Khuansuwan S
- Khundadze M
- Killackey SA
- Kim D
- Kim D-E
- Kim D-H
- Kim DR
- Kim E-K
- Kim EY
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- Tang D
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- Velasco G
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- Visnjic D
- Vitale I
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- Voitsekhovskaja OV
- Volonté C
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- Von Haefen C
- Vooijs MA
- Voos W
- Vucicevic L
- Wade-Martins R
- Waguri S
- Waite KA
- Wakatsuki S
- Walker DW
- Walker MJ
- Walker SA
- Walter J
- Wandosell FG
- Wang B
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- Wang C
- Wang C-Y
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- Wang D
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- Yazdankhah M
- Yen PM
- Yi C
- Yi-Ren Hong C-WH
- Yin X-M
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- Yip CK
- Yiu SPT
- Yoo YH
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- Yoshimori T
- Yousefi B
- Yu B
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- Yue J
- Yue Z
- Yun J
- Yung RL
- Zacks DN
- Zaffagnini G
- Zambelli VO
- Zanella I
- Zang QS
- Zanivan S
- Zappavigna S
- Zaragoza P
- Zarbalis KS
- Zarebkohan A
- Zarrouk A
- Zeitlin SO
- Zeng J
- Zeng J-D
- Zhan L
- Zhang B
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- Zhang J-P
- Zhang KYB
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- Zhang M
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- Zhang S
- Zhang W
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X-W
- Zhang XD
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y-D
- Zhang Y-Y
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhao H
- Zhao L
- Zhao S
- Zhao T
- Zhao X-F
- Zhao Y
- Zhao Y
- Zhao Y
- Zhao Y
- Zheng G
- Zheng K
- Zheng L
- Zheng S
- Zheng X-L
- Zheng Y
- Zheng Z-G
- Zhivotovsky B
- Zhong Q
- Zhou A
- Zhou B
- Zhou C
- Zhou G
- Zhou H
- Zhou H
- Zhou H
- Zhou J
- Zhou J
- Zhou J
- Zhou J
- Zhou K
- Zhou R
- Zhou X-J
- Zhou Y
- Zhou Y
- Zhou Y
- Zhou Z
- Zhou Z-Y
- Zhu B
- Zhu C
- Zhu G-Q
- Zhu H
- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Álvarez ÉMC
- Ávalos Y
- Önal G
- Üstün S
- Čolić M
- Đokić J
- Žerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Evaluation of the effect of miltefosine on Trichomonas vaginalis
- Author
- A Kuhlencord
- B Pol Van Der
- C Blaha
- D Soper
- DI Edwards
- Débora Afonso Silva Rocha
- F Sorvillo
- F Sorvillo
- F Widmer
- HG Bertão
- IA Rosa
- Ivone de Andrade Rosa
- J Kulda
- J Soto
- J Soto
- J Walochnik
- JC Noel
- JD Smilack
- JG Lossick
- JG Meingassner
- K Seifert
- LS Diamond
- M Muller
- Marlene Benchimol
- MB Martin
- MF Cotch
- MG Cabrera-Serra
- ML Kurohara
- MM Eissa
- MM Eissa
- MM Eissa
- N Shakya
- N Shakya
- P Escobar
- P Hilgard
- R Lira
- RF Madeiro da Costa
- RM Mariante
- RM Mariante
- RM Santa-Rita
- RM Santa-Rita
- S Clive
- S Khademvatan
- S Sutcliffe
- SC Robinson
- SL Croft
- SL Croft
- T Meri
- TK Jha
- VB Saraiva
- VB Saraiva
- VJ Johnston
- Wanderley de Souza
- WE Secor
- X Serrano-Martín
- ZA Polat
- ZF Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Evaluation of Viral Recovery Methodologies from Solid Waste Landfill Leachate
- Author
- A Allard
- A Carducci
- A Hundesa
- A Pal
- A Stals
- AM Costa
- APHA
- B Calgua
- B Calgua
- B Calgua
- BE Hernroth
- CF Mannarino
- CP Gerba
- CP Gerba
- E Grisey
- E Haramoto
- E Rames
- EPA U.S.
- G Tchobanoglous
- HD Silva
- HEO Soares
- J Hewitt
- J Jianguo
- J Martín-Díaz
- JA Platts-Mills
- K Kovac
- K Singh
- K Wong
- KL Opel
- LSMS Lima
- M D’Almeida
- M Howard
- MH Hjelmsø
- PR O’leary
- R Boom
- RM Martins
- S Bofill-Mas
- S Bofill-Mas
- S Kumar
- S Pina
- SR Qasim
- T Prado
- TA Marinho
- TA Marinho
- TG Bulc
- TG Metcalf
- VB Rajal
- X Fernandez-Cassi
- Z Han
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Pretreatment of Sugarcane Bagasse and Leaves: Unlocking the Treasury of “Green Currency”
- Author
- A Pandey
- AK Chandel
- AK Chandel
- AK Chandel
- AK Chandel
- AK Chandel
- AK Chandel
- AK Chandel
- AM Azzam
- AS da Silva
- ATWM Hendriks
- B Buaban
- B Sarrouh
- BA Prior
- BG Fonseca
- BP Lavarack
- C Carrasco
- C Krishnan
- C Martín
- CF Liu
- EC Rivera
- F Carvalheiro
- F Xu
- FM Gírio
- G Brodeur
- GA Aita
- GJM Rocha
- H Olivier-Bourbigou
- K Ojeda
- L Canilha
- L Mesa
- L Mesa
- L Wu
- L Wu
- M Brienzo
- M Laser
- ME Himmel
- MJ Taherzadeh
- MOS Dias
- N Moiser
- N Narayanaswamy
- N Sarkar
- P Alvira
- P Binod
- P Kumar
- RFH Dekker
- RJ Brugnago
- RK Singh
- S Chen
- S Kim
- S Ma
- SA Silva
- SC Rabelo
- SM Costa
- SPS Chundawat
- T Eggeman
- T Jeoh
- V Ferreira-Leitao
- VB Agbor
- WC Neely
- WE Karr
- X Zhao
- X Zhao
- XB Zhao
- Y Sun
- Y Zheng
- Y Zheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Enema syringes in South Andean hallucinogenic paraphernalia: evidence of their use in funerary contexts of the Atacama and neighboring zones (ca. AD 500–1500)
- Author
- A Llagostera
- A Llagostera
- A Llagostera
- AE Nielsen
- AE Nielsen
- AG Hogg
- Alejandra Vidal
- Alethia Quirgas
- AR Cortella
- C Bronk Ramsey
- CM Torres
- CM Torres
- CM Torres
- CM Torres
- CM Torres
- CM Torres
- CM Torres
- CM Torres
- CM Torres
- D González-Holguín
- E Nordenskiöld
- F Gili
- H Horta
- H Horta
- H Horta
- H Horta
- H Larraín
- Helena Horta-Tricallotis
- J Berenguer
- J Berenguer
- J Ott
- J Ott
- J Pérez Gollán
- Javier Echeverría
- JB Ambrosetti
- K Prost
- M Hubbe
- M Uhle
- M Uhle
- M Uhle
- ML Pochettino
- P Duviols
- PAGM De Smet
- PAGM De Smet
- PH Bethell
- R Lehmann-Nitsche
- RE Schultes
- RE Schultes
- S Pastor
- SH Wassén
- V Lema
- VB Martín Silva
- Verónica Lema
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Recent Advances in Sugarcane Industry Solid By-Products Valorization
- Author
- A Abd-Alla
- A Bhatnagar
- A Bonomi
- A Dumbrepatil
- A Fangkum
- A Ghimire
- A Gupta
- A Hendriks
- A Hideno
- A Moubarik
- A Pandey
- A Petit
- A Rahman
- A Rodrı́guez-Chong
- A Singh
- AA Guilherme
- AK Chandel
- AK Chandel
- AK Chandel
- AM Castro de
- AM Contreras
- AMF Milagres
- ASA Silva da
- B Buaban
- B Eyheraguibel
- B Hahn-Hägerdal
- B Radjaram
- B Radjaram
- B Yang
- BEL Baêta
- BS Moraes
- BS Moraes
- C Krishnan
- C Mack
- C Martin
- C Martin
- C Martín
- C Martín
- C Martín
- C Sambusiti
- C Somerville
- C Sánchez
- C-F Liu
- CA Cardona
- CA Rezende
- CC Geddes
- CE Wyman
- CN Hamelinck
- CS Goh
- CZ Lazaro
- D Kalaivanan
- D Kalderis
- D Khatiwada
- D Kumar
- D Pasquini
- D Pasquini
- D Silva
- D Wei
- D-H Kim
- DA Bocchini
- DA Cerqueira
- DDS Santos Dos
- DR Mulinari
- E Khoramzadeh
- E Pehlivan
- EC Giese
- EM Rubin
- ER Borges
- ES Martins
- F Carvalheiro
- F Mandelli
- F Paoli De
- F Peng
- F Shen
- F Veana
- FMV Oliveira
- FR Hawkes
- G Rajagopalan
- G Ramadoss
- GA Aita
- GJ Moraes Rocha de
- GJ Moraes Rocha de
- GJM Rocha
- GJM Rocha
- GP Maitan-Alfenas
- GP Walsum van
- H Gebre
- H Palonen
- H-C Tao
- HM Baudel
- I Alomá
- I Ullah
- J Cassia Pereira
- J Cheng
- J Wang
- J Wang
- J-X Yu
- JA Rodriguez
- JM Hernández-Salas
- JN Nigam
- K Khosravi-Darani
- K Rana
- K Urbaniec
- K-K Cheng
- KAG Gusmão
- KB Ansari
- L Capecchi
- L Janke
- L Janke
- L Janke
- L Jiang
- L Laureano-Perez
- L Liang
- LA Oliveira
- LAR Batalha
- LG Pereira
- LH Silva Martins da
- LM López González
- LML González
- LML González
- LP Ramos
- LVA Gurgel
- LVA Gurgel
- M Balakrishnan
- M Camassola
- M Dominguez
- M Fox
- M Galbe
- M Jiang
- M Khwairakpam
- M Kurakake
- M Laser
- M Mohamad
- M Prakash
- MA Abdel-Rahman
- MA Mazutti
- MA Rouf
- MA Rouf
- MC Vargas-Garcı
- ME Vallejos
- MG Adsul
- MJ Taherzadeh
- MJ Taherzadeh
- MJ Taherzadeh
- MM Souza Moretti de
- MOS Dias
- N Esfandiar
- N Gupta
- N Joshi
- N Martin
- N Mosier
- N Nava-Valente
- N Partha
- N Sarkar
- N Suma
- NK Amin
- O Karnitz
- O Karnitz
- OK Júnior
- OV Singh
- P Alvira
- P Binod
- P Börjesson
- P Das
- P Kumar
- P Laopaiboon
- P Miretzky
- P Pandey
- P Rattanapoltee
- P Sangwan
- P Singh
- P Torre
- PC Brandão
- PC Hallenbeck
- PK Rai
- PKD Mohapatra
- PL Homagai
- Q Yu
- Q Yu
- Q Yu
- Q Yu
- R Ayyappan
- R Behnood
- R Chandra
- R Cifuentes
- R Kumar
- R Kumar
- R Kumar
- R Liu
- R Sindhu
- RC McWilliams
- RK Sukumaran
- RP John
- RR Singhania
- S Behera
- S Bolado-Rodríguez
- S Gámez
- S Karellas
- S Kaur
- S Kumari
- S Ou
- S Pattra
- S Solomon
- S Zaheer
- S Zhu
- SA Bhat
- SC Rabelo
- SH Cruz Da
- SI Mussatto
- SPS Chundawat
- SR Couto
- SV Mahamuni
- T Botha
- T Eggeman
- TC Sarker
- TC Sarker
- TL Junqueira
- TV Ojumu
- U Garg
- UF Rodríguez-Zúñiga
- UK Garg
- VB Agbor
- X Niu
- X Zhao
- X Zhao
- X Zhao
- X Zhao
- XB Zhao
- Y Huang
- Y Lin
- Y Liu
- Y Liu
- Y Sun
- Y Xing
- Y Zhao
- Y Zheng
- Y-L Xi
- Y-T Fan
- Z Lai
- Z Qiu
- Z Zhang
- Z Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Sugarcane is among the leading agricultural crop cultivated in tropical regions of the world. Industrial processing of sugarcane generates sugar; as well as various solid wastes (i.e. sugarcane bagasse, pressmud). Improvement of biotechnology in industrial level, offers opportunities for economic utilization of these solid residues. In the last few decades, sugarcane bagasse and pressmud have been explored in the theme of lignocellulosic bioconversion. The recalcitrance of biomass is a major drawback towards successful exploitation of lignocellulosic residues. Pretreatment by suitable/efficient processes can overcome this limitation. In this regards; physical, chemical and biological treatment systems are brought into our perspective. Chemical and physicochemical methods are capital-intensive but not environment-friendly, in contrast, method like biological treatment is eco-friendly but extremely slow. There are still major technological and economic challenges need to be addressed; e.g. bioprospecting, established more reliable genetically modified microorganisms, upgrade gene cloning and sequencing processes, yield improvement at large scale etc. Productions of value-added products from these solid wastes are discussed in such a way that pinpoints the most recent trends and the future directions. Biofuels, enzymes, organic acids and bio-sorbents production draw a clear sketch of the current and future bio-based products. Nano-biotechnology and genetic engineering could be future trends to improved processes and products. This review serves as a valuable reference material for a wide range of scientists and technologists in the relevant fields
Lignocellulosic Biomass-Based Biorefinery: an Insight into Commercialization and Economic Standout
- Author
- A Giuliano
- A Giuliano
- A Hasanly
- A Mirkouei
- A Rodrigues Gurgel da Silva
- A Sultana
- AK Chandel
- ATWM Hendriks
- AV Brandt-Talbot
- AW Bhutto
- B Brigljević
- B Dale
- B Kumar
- B Yang
- C Huang
- C Ma
- CG Yoo
- CS Osorio-González
- CS Osorio-González
- D Kumar
- E Mupondwa
- E Searcy
- E Van Doorslaer
- F Cherubini
- F Passos
- F Talebnia
- G Yao
- G-C Xu
- GJ Antonio
- H Wang
- H Zabed
- H-W Yen
- HM Zabed
- HQ Lê
- IJ Okeke
- J Ariunbaatar
- J English
- J Li
- J Littlejohns
- J Rocha-Martín
- JJ Quiroz-Ramírez
- JM Rieland
- K Sanford
- KD Hannam
- L Zhao
- LJ Jönsson
- LV Daza Serna
- M Karimi Alavijeh
- M Patel
- M Patel
- M Raud
- M Röder
- M Song
- M Ter-Mikaelian
- M Zdanowicz
- MFF Rodrigues
- MT Ross
- MT Ter-Mikaelian
- N Dave
- N LJR
- NA Boakye-Boaten
- NR Baral
- NT Albashabsheh
- PS Sabaini
- Q Fei
- R García
- R Poontawee
- R Shen
- R Sindhu
- S Paul
- SA Jambo
- SG Mungodla
- SM Sen
- SS Hassan
- TL Junqueira
- TM Thompson
- V Keller
- VB Agbor
- VK Ponnusamy
- Y Liu
- Y Nie
- Z Wu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Recent Advances in Sugarcane Industry Solid By-Products Valorization
- Author
- A Abd-Alla
- A Bhatnagar
- A Bonomi
- A Dumbrepatil
- A Fangkum
- A Ghimire
- A Gupta
- A Hendriks
- A Hideno
- A Moubarik
- A Pandey
- A Petit
- A Rahman
- A Rodrı́guez-Chong
- A Singh
- AA Guilherme
- AK Chandel
- AK Chandel
- AK Chandel
- AM Castro de
- AM Contreras
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- ASA Silva da
- B Buaban
- B Eyheraguibel
- B Hahn-Hägerdal
- B Radjaram
- B Radjaram
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- BS Moraes
- C Krishnan
- C Mack
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- C Martin
- C Martín
- C Martín
- C Martín
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- C-F Liu
- CA Cardona
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- D Kalaivanan
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- D Pasquini
- D Pasquini
- D Silva
- D Wei
- D-H Kim
- DA Bocchini
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- DR Mulinari
- E Khoramzadeh
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- F Carvalheiro
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- F Peng
- F Shen
- F Veana
- FMV Oliveira
- FR Hawkes
- G Rajagopalan
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- GA Aita
- GJ Moraes Rocha de
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- GJM Rocha
- GJM Rocha
- GP Maitan-Alfenas
- GP Walsum van
- H Gebre
- H Palonen
- H-C Tao
- HM Baudel
- I Alomá
- I Ullah
- J Cassia Pereira
- J Cheng
- J Wang
- J Wang
- J-X Yu
- JA Rodriguez
- JM Hernández-Salas
- JN Nigam
- K Khosravi-Darani
- K Rana
- K Urbaniec
- K-K Cheng
- KAG Gusmão
- KB Ansari
- L Capecchi
- L Janke
- L Janke
- L Janke
- L Jiang
- L Laureano-Perez
- L Liang
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- LM López González
- LML González
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- LVA Gurgel
- LVA Gurgel
- M Balakrishnan
- M Camassola
- M Dominguez
- M Fox
- M Galbe
- M Jiang
- M Khwairakpam
- M Kurakake
- M Laser
- M Mohamad
- M Prakash
- MA Abdel-Rahman
- MA Mazutti
- MA Rouf
- MA Rouf
- MC Vargas-Garcı
- ME Vallejos
- MG Adsul
- MJ Taherzadeh
- MJ Taherzadeh
- MJ Taherzadeh
- MM Souza Moretti de
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- N Esfandiar
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- N Partha
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- NK Amin
- O Karnitz
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- OV Singh
- P Alvira
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- P Miretzky
- P Pandey
- P Rattanapoltee
- P Sangwan
- P Singh
- P Torre
- PC Brandão
- PC Hallenbeck
- PK Rai
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- PL Homagai
- Q Yu
- Q Yu
- Q Yu
- Q Yu
- R Ayyappan
- R Behnood
- R Chandra
- R Cifuentes
- R Kumar
- R Kumar
- R Kumar
- R Liu
- R Sindhu
- RC McWilliams
- RK Sukumaran
- RP John
- RR Singhania
- S Behera
- S Bolado-Rodríguez
- S Gámez
- S Karellas
- S Kaur
- S Kumari
- S Ou
- S Pattra
- S Solomon
- S Zaheer
- S Zhu
- SA Bhat
- SC Rabelo
- SH Cruz Da
- SI Mussatto
- SPS Chundawat
- SR Couto
- SV Mahamuni
- T Botha
- T Eggeman
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- U Garg
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- X Niu
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- Y Huang
- Y Lin
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- Y Liu
- Y Sun
- Y Xing
- Y Zhao
- Y Zheng
- Y-L Xi
- Y-T Fan
- Z Lai
- Z Qiu
- Z Zhang
- Z Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Transplantation in the Tropics: Lessons on Prevention and Management of Tropical Infectious Diseases
- Author
- A Alves da Silva
- A Basiri
- A Gratwohl
- A Komitopoulou
- A Moncayo
- A Olsen
- A Prata
- A Riarte
- A Zandieh
- AA Sousa
- AC Currie
- AC Roxby
- AD Kitchen
- AI Fiorelli
- AK Subramanian
- AM Roselino
- AS Lemos De
- B Chacko
- B Wyplosz
- BK Mandal
- BS Schwartz
- C Bern
- C Choonhakarn
- C Franco-Paredes
- C Maldonado
- C Martínez-Losada
- C Mary
- C Nguyen
- C Valar
- C White
- Camille N. Kotton
- CI Cura
- CJ Renaud
- CM Machado
- CMC Oliveira
- CMF Gontijo
- CN Kotton
- D Bumbacea
- D Lopez de Castilla
- D Ozcan
- D Vucicevic
- DR Kaul
- E Blodget
- E Canet
- E Hernández-Hernández
- E O’Riordan
- EA Bocchi
- EC Moreno
- EG Vilela
- F Bacal
- F Bemelman
- F Lefrère
- F Pieroni
- F Schär
- FF Tuon
- FL-S Tan
- G Bautista
- G Michel
- G Roustan
- GVR Prasad
- H Appassakij
- H Arslan
- HR Vikram
- I Simon
- IDB Marques
- J Altclas
- J Alvar
- J Griensven Van
- J Hernández-Pérez
- J Inoue
- J Lin
- J Torre-Cisneros
- J-L Wang
- JE Blair
- JE Blair
- JE Blair
- JE Blair
- JG Rigau-Pérez
- JM Aguado
- JS Schieffelin
- K Dierberg
- K Modi
- L Chiche
- L Danziger-Isakov
- L McCormack
- LA Silva
- LAC D’Albuquerque
- LB Gasink
- Ligia C. Pierrotti
- LL Dias
- LS Azevedo
- LS Azevedo
- M Diez
- M Fernández-Ruiz
- M Le
- M Mungai
- M Punzel
- M Rodriguez
- M Tomblyn
- M Veroux
- MA Assi
- MAB Trindade
- MC Lanteri
- ME Elsharif
- ME Levi
- MG Teixeira
- MI Morris
- ML Nguyen
- MM Otani
- MV Batista
- MV Batista
- N Boillat-Blanco
- N Mendoza
- N Prasad
- N Sabé
- N Singh
- N Singh
- O Len
- O Manuel
- OC Moreira
- P Martín-Dávila
- P Muñoz
- PA Tambyah
- PCY Woo
- PJ Hotez
- PK Jha
- PV Chin-Hong
- R Cámara De la
- R Lattes
- R Lattes
- R Naqvi
- R Naqvi
- R Valdez-Ortiz
- RA Oliveira
- S Antinori
- S Antinori
- S Guditi
- S Huprikar
- S Huprikar
- S Talhari
- SA Araujo
- SA Fischer
- SK Agarwal
- SL Kokseng
- SL Kokseng
- SL Stramer
- SV Campos
- SY Kim
- T Couderc
- T Duffy
- TJ Glenn
- V Nobre
- VB Kute
- VLT Freitas De
- W Clemente
- World Health Organization
- World Health Organization
- WT Clemente
- WT Clemente
- WT Clemente
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Clinical and genetic characteristics of late-onset Huntington's disease
- Author
- Aanonsen No
- Aaserud O
- Abbruzzese G
- Acera Gil Ma
- Ackermann O
- Adarmes A
- Agarwal V
- Agosti C
- Akhtar S
- Alaerts N
- Alarcón Md
- Albanese A
- Allain P
- Almagro Ca
- Almeida M
- Alonso-Frech F
- Alusi S
- Anderson M
- Andersson C
- Andrade C
- Andrew A
- Andrews T
- Andrews T
- Andrich J
- Anheim M
- Anjum U
- Anna Bryl Ja
- Annic A
- Antczak J
- Antequera Torres Mm
- Antonova V
- Arbelo Jm
- Arkuszewski M
- Armstrong R
- Armstrong R
- Arntsen V
- Arques Pn
- Arran N
- Azulay Jp
- Baake V
- Babiloni B
- Bachmeier M
- Bachoud-Lévi Ac
- Bachoud-Lévi Ac
- Badei F
- Bailey W
- Banaszkiewicz K
- Bandettini di Poggio M
- Bandmann O
- Barbera Ma
- Barker Ra
- Barlati S
- Barral Vm
- Barrero F
- Barrett W
- Barth K
- Barth K
- Barthélémy R
- Bartoli C
- Barun N
- Bas J
- Bascuñana M
- Becanovic K
- Bechtel N
- Beckmann H
- Bek J
- Bellonet M
- Benaich S
- Benaminov S
- Benito Dm
- Bentivoglio Ar
- Bentivoglio Ar
- Berglund M
- Berglund M
- Berglund P
- Bergmann U
- Bernal-Escudero M
- Bernard T
- Bertini E
- Bethwaite P
- Betz S
- Beuth M
- Bezdíček O
- Bijlsma Emilia K
- Bioux S
- Biunno I
- Björnsson E
- Bjørgo K
- Bjørnevoll I
- Bled D
- Bliaux E
- Blin S
- Blinkenberg Eø
- Blondeau L
- Boczarska-Jedynak M
- Boelmans K
- Bohlen S
- Boissé Mf
- Bojakowska-Jaremek K
- Bojarsky Jk
- Bonelli Rm
- Bonelli Rm
- Bonelli Rm
- Bonneau D
- Boogaerts A
- Boogaerts A
- Borgerød N
- Bos R
- Bos R
- Bosca M
- Bosredon C
- Bost M
- Boster S
- Boudali L
- Bove F
- Boćwińska D
- Bradbury A
- Braunwarth Em
- Brice A
- Brockie P
- Bronzova J
- Brown P
- Brugada Fc
- Brugger F
- Bruno S
- Bruun A
- Buchanan L
- Buck A
- Buongiorno Mt
- Buratti L
- Burguera Ja
- Burgunder Jm
- Burgunder Jm
- Burgunder Jm
- Burn J
- Burrows L
- Busquets N
- Busse M
- Butcher C
- Bárcenas Ah
- Böringer R
- Bürk K
- Błaszczyk M
- Cabaret M
- Calado A
- Calandra-Buonaura G
- Caldentey Jg
- Caldentey Jg
- Caldentey Jg
- Callaghan J
- Callaghan J
- Callaghan J
- Calmeyn G
- Calopa M
- Calvas F
- Calzado N
- Campolongo A
- Cannella M
- Capellari S
- Capetian P
- Capodarca S
- Cardoso H
- Carette As
- Carrillo F
- Carrière N
- Carruesco Gt
- Casado Rv
- Cass G
- Castagliuolo S
- Castaldo A
- Catalli C
- Catena Jl
- Cavaco S
- Cação G
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- Chen S
- Cheriet S
- Chiara P
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- Chu E
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- Ciesielska A
- Classen Sj
- Clayton C
- Clenaghan C
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- Coarelli G
- Codella V
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- Coelho M
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- Cubillo Pt
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- Damásio J
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- de Die-Smulders Christine Em
- De Gregorio F
- De Michele G
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- de Raedt S
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- de Tommaso M
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- Dec M
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- Deith C
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- Delabaere H
- Delaigue C
- Delfini M
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- Delval A
- Delvaux I
- Demonet Jf
- Depelchin A
- Derost P
- Descals Am
- Destee A
- Dewulf-Pasz N
- Di Bella D
- Di Donato S
- Di Giacopo R
- Di Maio L
- Di Maria E
- Di Renzo M
- Diago Eb
- Dias M
- Diercks G
- Difruscolo O
- Dipple H
- Dixon K
- Dixon K
- Diéguez E
- Doherty K
- Dondaine T
- Donovan Jo
- Dose M
- Dougherty A
- Downie L
- Dramstad E
- Dressler D
- Duché C
- Duffell A
- Dugauquier F
- Duits A
- Dujardin K
- Dumas Em
- Dunnett S
- Dunnett Sb
- Duport S
- Dupuis M
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- Durr A
- Dziadkiewicz A
- Ecker D
- Ecker D
- Eddy C
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- El-Nimr G
- Elifani F
- Ellrichmann G
- Esmaeilzadeh M
- Esposito C
- Esposito F
- Eusebio A
- Evans C
- Ewenczyk C
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- Fannemel M
- Fasano A
- Feliz C
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- Ferrandes G
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- Ferreira Jj
- Ferrer Pq
- Figorilli M
- Figuerola Bj
- Fillingham K
- Finisterra Am
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- Fletcher A
- Fluchere F
- Formerly Rödig Vb
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- Fortunato F
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- Foustanos I
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- Frontali M
- Frost J
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- Gallantree D
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- García de Yébenes J
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- García A
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- Geitner C
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- Gillardin Af
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- Ginestroni A
- Girard C
- Giuliano J
- Goerendt I
- Gogol Formerly Kalbarczyk A
- Gohier B
- Goizet C
- Golding C
- Golding C
- Gomez Esteban Jc
- González A
- González S
- Gonçalves A
- Good Jm
- Goodman A
- Gorzkowska A
- Gorzolla H
- Gosling Nee Brown S
- Goudie D
- Gowers L
- Grabska N
- Guedes Lc
- Guedes Lc
- Guenam A
- Guia Db
- Guidubaldi A
- Guimarães J
- Guisasola Lm
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- Guyant-Maréchal L
- Guzman Nv
- Guérid Ma
- Göller Ml
- Göpfert N
- Gørvell Pf
- Haggag K
- Haider S
- Haig-Brown D
- Haig-Brown D
- Hallam C
- Hamer S
- Hamer S
- Hametner Em
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- Hannequin D
- Hannier V
- Harding A
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- Hare M
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- Harrower T
- Hartikainen P
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- Hauge E
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- Heiberg A
- Heiberg A
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- Herranhof B
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- Herrmann L
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- Horta A
- Hotter A
- Howard L
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- Hunt S
- Huson S
- Hussain H
- Hussl A
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- Hyppönen H
- Hölzner E
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- Illarioshkin S
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- Kaiserova M
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- Maass A
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- Petracca M
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- Phillipps C
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- Pica E
- Piedad J
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- Pinter B
- Piras V
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- Poda R
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- Polo Cg
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- Porteous M
- Pouliquen D
- Powell K
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- Robert Mf
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- Rohm S
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- Romero I
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- Romoli Am
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- Roos Ra.
- Roos Rac
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- Rose S
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- Roth J
- Rothery J
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- Rowett L
- Rowett L
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- Rudolf G
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- Sablonnière B
- Saft C
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- Stárková I
- Städtler M
- Størseth Hh
- Stępniak I
- Summers F
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- Viladrich Cm
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- Wallden T
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- Weekes R
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- Zdzienicka E
- Zea Sevilla Ma
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- Zielonka D
- Zielonka D
- Zielonka E
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- Zinzi P
- Zinzi P
- Ziora-Jakutowicz K
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- Åman J
- Østern R
- Šašinková P
- Šenkárová Z
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background: The frequency of late-onset Huntington's disease (>59 years) is assumed to be low and the clinical course milder. However, previous literature on late-onset disease is scarce and inconclusive. Objective: Our aim is to study clinical characteristics of late-onset compared to common-onset HD patients in a large cohort of HD patients from the Registry database. Methods: Participants with late- and common-onset (30\u201350 years)were compared for first clinical symptoms, disease progression, CAG repeat size and family history. Participants with a missing CAG repeat size, a repeat size of 6435 or a UHDRS motor score of 645 were excluded. Results: Of 6007 eligible participants, 687 had late-onset (11.4%) and 3216 (53.5%) common-onset HD. Late-onset (n = 577) had significantly more gait and balance problems as first symptom compared to common-onset (n = 2408) (P <.001). Overall motor and cognitive performance (P <.001) were worse, however only disease motor progression was slower (coefficient, 120.58; SE 0.16; P <.001) compared to the common-onset group. Repeat size was significantly lower in the late-onset (n = 40.8; SD 1.6) compared to common-onset (n = 44.4; SD 2.8) (P <.001). Fewer late-onset patients (n = 451) had a positive family history compared to common-onset (n = 2940) (P <.001). Conclusions: Late-onset patients present more frequently with gait and balance problems as first symptom, and disease progression is not milder compared to common-onset HD patients apart from motor progression. The family history is likely to be negative, which might make diagnosing HD more difficult in this population. However, the balance and gait problems might be helpful in diagnosing HD in elderly patients