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Current epidemiological profile of chagasic megaesophagus in central Brazil
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Previous issue date: 2013-06Introduction: Chagasic megaesophagus (CM) is the most common digestive manifestation of Chagas disease in Brazil, and
the State of Goiás is one of the most affected regions. In recent decades, the Hospital das Clínicas (HC)/Universidade Federal
de Goiás (UFG) has been a reference center for the study and treatment of CM. The objective of this study was to characterize
the current epidemiological profi le of patients with CM observed at the HC of the UFG from 1998 to 2010. Methods: In total,
939 patient records were analyzed, and age, gender, place of birth, serology, symptoms and radiological classifi cation according
to Rezende et al. were analyzed. Results: The median patient age was 55 years. Male patients were more (54%) prevalent than
female patients. The prevalence of younger patients (less than 31 years of age) was 4.2%, but 82.1% of the younger patients were
from State of Bahia. Patients older than 40 years were the majority (85.5%). The radiological groups were distributed as follows:
Group I (35.9%), Group II (32.9%), Group III (17%) and Group IV (14.2%). Conclusions: Compared with previous studies by
the same group in 1975, 1994 and 1995, the number of younger patients decreased, and the frequency curve has shifted to older
patients
A viagem científica de Neiva e Penna: roteiro para os estudos das doenças do sertão The scientific journey taken by Neiva and Penna: a blueprint for studies of diseases from the Brazilian hinterland
Analisa o relatório de Arthur Neiva e Belisario Penna , focalizando a contribuição dos autores ao estudo de uma das doenças endêmicas por eles encontrada ao longo de todo o trajeto percorrido, de longa data conhecida popularmente por 'mal de engasgo'. Observaram e descreveram com minúcia os sintomas apresentados pelos doentes e a associação frequente do mal de engasgo com outro mal endêmico conhecido por 'vexame' ou 'vexame do coração', que consistia em crises de palpitações. Os estudos epidemiológicos e clínicos de Neiva e Penna sobre o mal de engasgo muito contribuíram para o conhecimento dessa afecção e representaram um incentivo para todos os pesquisadores que se dedicaram ao seu estudo, especialmente quanto a sua relação com a doença de Chagas.<br>Analyze the report by Neiva and Penna, focusing on the contribution these authors made to the study of one of the endemic diseases encountered throughout their journey, which had been long known under the popular name of mal de engasgo (choking disease). They recorded their observations and detailed descriptions of the patients' symptoms and the association frequently encountered between mal de engasgo and another endemic disease, known as vexame or vexame do coração, characterized by bouts of palpitations. Neiva and Penna's epidemiological and clinical observations of mal de engasgo were crucial for all the researchers interested in the disease, especially its relationship with Chagas disease