254 research outputs found
On Gymnodactylus amarali Barbour, 1925, with the description of a new species (Sauria, Gekkonidae)
Factual news: como agir direito
Divulgação dos SUMĂRIOS das obras recentemente incorporadas ao acervo da Biblioteca Ministro Oscar Saraiva do STJ. Em respeito Ă Lei de Direitos Autorais, nĂŁo disponibilizamos a obra na Ăntegra.Localização na estante: 34:004.738.5(81) F142nOrganizado por: Ana ClĂĄudia Silva Scalquette, PatrĂcia Vanzolini, Renata da Rocha e Rodrigo Arnoni Scalquett
A new humanized antibody is effective against pathogenic fungi in vitro
Invasive fungal infections mainly affect patients undergoing transplantation, surgery, neoplastic disease, immunocompromised subjects and premature infants, and cause over 1.5 million deaths every year. The most common fungi isolated in invasive diseases are Candida spp., Cryptococcus spp., and Aspergillus spp. and even if four classes of antifungals are available (Azoles, Echinocandins, Polyenes and Pyrimidine analogues), the side effects of drugs and fungal acquired and innate resistance represent the major hurdles to be overcome. Monoclonal antibodies are powerful tools currently used as diagnostic and therapeutic agents in different clinical contexts but not yet developed for the treatment of invasive fungal infections. In this paper we report the development of the first humanized monoclonal antibody specific for beta-1, 3 glucans, a vital component of several pathogenic fungi. H5K1 has been tested on C. auris, one of the most urgent threats and resulted efficient both alone and in combination with Caspofungin and Amphotericin B showing an enhancement effect. Our results support further preclinical and clinical developments for the use of H5K1 in the treatment of patients in need
Parthenogenesis In The Tropical Gekkonid Lizard, Nactus Arnouxii (Sauria: Gekkonidae)
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137400/1/evo02464.pd
Chemical composition and acaricidal activity of the leaf and fruit essential oils of Protium heptaphyllum (Aubl.) Marchand (Burseraceae)
Reproduction of Oligosarcus hepsetus (Cuvier, 1829) (Characiforms) in the Serra do Mar State Park, SĂŁo Paulo, Brazil
Physiological quality of soybean and wheat seeds produced with alternative potassium sources
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