Serum collagen triple helix repeat-containing (CTHRC1) levels is associated with circulating stem cell factor and pro-inflammatory cytokines in rheumatoid arthritis

Everyday monitoring disease activity of chronic inflammatory diseases such as Rheumatoid Arthritis (RA) is a tempting approach for every patient for attaining personalized treatment strategies. Still underdeveloped area of RA biomarkers needs sensitive and specific analytes. CTHRC1 was found earlier expressed in activated synoviocytes and present in circulation that makes it potential valuable RA marker

Serum collagen triple helix repeat-containing (CTHRC1) levels is associated with circulating stem cell factor and pro-inflammatory cytokines in rheumatoid arthritis

Everyday monitoring disease activity of chronic inflammatory diseases such as Rheumatoid Arthritis (RA) is a tempting approach for every patient for attaining personalized treatment strategies. Still underdeveloped area of RA biomarkers needs sensitive and specific analytes. CTHRC1 was found earlier expressed in activated synoviocytes and present in circulation that makes it potential valuable RA marker

Elevated levels of plasma collagen priple helix repeat-containing (CTHRC1) protein correlates with increased granul ocytopoiesis and higher rheumatoid arthritis disease severity score

Monitoring and suppressing activity of the pathological granulating pannus tissue is essential for Rheumatoid Arthritis (RA) management. Synovial joints pain and tissue destruction is a derivative of the pannus activity. In a mouse model for RAwe found CTHRC1, a secreted and circulating protein, to be inducible in arthritis and correlated with the disease severity. We performed a clinical investigation to ascertain the role of CTHRC1 in the progression of the disease

Elevated levels of plasma collagen priple helix repeat-containing (CTHRC1) protein correlates with increased granul ocytopoiesis and higher rheumatoid arthritis disease severity score

Monitoring and suppressing activity of the pathological granulating pannus tissue is essential for Rheumatoid Arthritis (RA) management. Synovial joints pain and tissue destruction is a derivative of the pannus activity. In a mouse model for RAwe found CTHRC1, a secreted and circulating protein, to be inducible in arthritis and correlated with the disease severity. We performed a clinical investigation to ascertain the role of CTHRC1 in the progression of the disease