Peculiarities of electronic heat capacity of thulium cuprates in pseudogap state

Precise calorimetric measurements have been carried out in the 7 - 300 K temperature range on two ceramic samples of thulium 123 cuprates TmBa2Cu3O6.92 and TmBa2Cu3O6.70. The temperature dependence of the heat capacity was analyzed in the region where the pseudogap state (PGS) takes place. The lattice contribution was subtracted from the experimental data. The PGS component has been obtained by comparing electronic heat capacities of two investigated samples because the PGS contribution for the 6.92 sample is negligible. The anomalous behavior of the electronic heat capacity near the temperature boundary of PGS was found. It is supposed that this anomaly is due to peculiarities in N(E) function where N is the density of electronic states and E is the energy of carriers of charge.Comment: 12 pages, 3 Postscript figure

Problem of spreading fake information in the Internet space analysis

Modern Internet space is filled with various kinds of information, including unreliable, fake information. In the current socio-cultural, socio-political, and socio-economic conditions, we should expect further increase in the spread of fakes and, as a consequence, their negative impact on people’s lives. The article analyses results of a sociological study on the attitude of the Kursk region population to fakes spread in the Internet space. The empirical basis of the study is the results of the online questionnaire survey conducted in September 2022 in the Kursk region. The sample population of the study was 521 people living in the territory of Kursk and Kursk region. Fakes are becoming a real part of life in modern society. Residents of the region are constantly faced with inaccurate information. They recognize its danger and note that fakes nevertheless “attract” their attention. The current situation requires additional measures development to regulate dissemination of information in the Internet space

Нерешенные вопросы диагностики рестриктивного типа вентиляционных нарушений

The aim of this study was to determine diagnostic value of an algorithm for restrictive ventilation disorders recommended by the American Thoracic and European Respiratory Society. Methods. We analyzed pulmonary function tests of 148 patients with interstitial lung disease with increased lung elasticity and without airways obstruction. A specific type of restrictive disorders referred to as «non-classic», because it does not match existing diagnostic criteria, was observed in most patients (n = 86). The recommended diagnostic algorithm had low sensitivity (0.42) mainly due to a low informative value of spirometry (VC was within a normal range in 80% of patients with non-classic restrictive pattern).С целью определения эффективности алгоритма диагностики рестриктивного типа вентиляционных нарушений, рекомендованного Американским торакальным и Европейским респираторным обществами, проанализированы результаты легочных функциональных тестов у больных (n = 148) интерстициальными заболеваниями легких с отсутствием признаков обструкции дыхательных путей и повышенной эластичностью легких. В большинстве случаев (n = 86) наблюдался вариант рестриктивных нарушений, названный неклассическим, поскольку он не удовлетворял существующим диагностическим критериям. При использовании рекомендованного к применению алгоритма диагностики рестриктивного типа вентиляционных нарушений продемонстрирована низкая чувствительность (0,42). Основной причиной тому была недостаточная информативность спирометрии – у 80 % больных с неклассическим рестриктивным паттерном жизненной емкости легких показатели оставались в пределах нормальных значений

Normal-state resistivity anisotropy in underdoped RBa_2Cu_3O_{6+x} crystals

We have revealed new features in the out-of-plane resistivity rho_c of heavily underdoped RBa_2Cu_3O_{6+x} (R=Tm,Lu) single crystals, which give evidence for two distinct mechanisms contributing the c-axis transport. We have observed a crossover towards "metal-like" (d rho_c/d T > 0) behavior at the temperature T_m which quickly increases with decreasing doping. The "metal-like" conductivity contribution dominates at T < T_m and provides a saturation of the resistivity anisotropy, rho_c / rho_{ab}. The antiferromagnetic ordering is found to block this "metal-like" part of the c-axis conductivity and complete decoupling of CuO_2 planes, which may be the reason of superconductivity disappearance.Comment: RevTex, 4 pages including 4 eps figures. To be published in Phys.Rev.Let

Economic aspects of the fixed combinations of lipid lowering medicines in group risks patients

Relevance.  Cardio-vascular diseases (CVD) are the one of the main reasons of mortality and disability. Hypercholesterinemia is a factor of CVD progression, and thus it should be corrected. Combination of statin + ezetemib is an effective option of a medical technology for this purpose. Pharmacoeconomic analysis of rosuvastatin and ezetemib fixed combination (FC) has been performed in this work in comparison with free combination (FrC) of these drugs.Materials and methods. Modelling of FC vs FrC in groups of CVD risk has been performed on 1–5 years horizon based on the local epidemiologic published data with aim of economic analysis. Efficacy of FC and FrC, direct medical costs, including cost of drugs, hospitalizations etc. were taken into account also. ICER has been calculated and compared with willingness to pay.Results. FC usage instead FrC can prevent 2960–3055 deaths and 8880–9164 admissions to hospital caused CVD. FC decrease of ambulance cost as well as others direct medical expenditures in compare with FrC treatment on 9,3 bln RUR per 5 years. ICER has been calculated and has negative (dominant) result.Conclusion. FC usage is an economic dominant technology in compare with FrC for hypercholesterolemia control

STRUCTURE OF IXODES TICK COMMUNITIES AT THE CONTINENTAL PART OF SOUTH PRIMORYE TERRITORY AND RUSSIAN ISLAND

In April-June 2012 a collection and analysis of structure of Ixodes tick communities was performed in various biotopes at the Primorye Territory. Five tick species (Ixodes persulcatus Schulze, 1930, I. pavlovskyi Pomerantzev, 1946, Haemaphysalis concinna Koch, 1844, H. japonica douglasi Nuttall et Warburton 1915, Dermacentor silvarum Olenev, 1932) were revealed. It was shown that I. pavlovskyi was rare at the continental part of the Primorye Territory, but it often happened at the Russian island. On the Continent H. japonica douglasi prevailed over H. concinna in total collections. Correlation of these species at the Russian island was reversed. Distinctions in the structure of Ixodes tick communities, formed due to specificity of ecological conditions and. long enough isolation of the parasites' fauna at the island, could affect the ratio and. features of the causative agents of the human infectious diseases for which the carrier organism serves as the first environment

Возможности импульсной осциллометрии в диагностике обструкции дыхательных путей легкой степени выраженности

The aim of this study was to investigate a role of impulse oscillometry (IO) for detection of mild bronchial obstruction. Methods. The study involved 87 patients with different respiratory diseases. Bronchial obstruction according to spirometry results was found in 50 patients (the study group). The control group patients did not demonstrate any abnormalities in spirometry, body plethysmography and lung diffusing test. Results. An abnormal increase in frequency-dependent resistive component of respiratory impedance (Rrs) at the oscillation frequency of 5Hrz and 10 Hrz [both the relative oscillation frequency (Rrs5–Rrs20)/Rrs20 and the absolute oscillation frequency (Rrs5–Rrs20)] was found in patients with mild bronchial obstruction. The resonance frequency (fres) shifted towards higher frequency; reactance area (AX) increase and expiratory airflow (DXrs5) limitation were also found in those patients. Rrs5, Rrs20, and the reactive resistance (Xrs5) were within the normal range. Conclusion. Rrs5 и Xrs5 could detect mild bronchial obstruction only in 32 % of the cases. AX is more useful parameter as it increased in 64% of the patients. The severity of bronchial obstruction diagnosed with IO or spirometry was not identical in some cases.Нередко начальным проявлением заболеваний легких являются функциональные нарушения, а именно – нарушение проходимости бронхов. Выявление обструктивного типа вентиляционных расстройств на ранних стадиях является важной клинической задачей, т. к. позволяет своевременно диагностировать болезнь и начать лечение, улучшив тем самым прогноз заболевания. Одним из самых доступных методов, позволяющих выявлять бронхиальную обструкцию, является спирометрия. Необходимое условие проведения спирометрии – правильное выполнение дыхательных маневров, однако при этом требуется хорошая кооперация пациента с медицинским персоналом, что не всегда выполнимо. Импульсная осциллометрия (ИОМ) отличается тем, что измерения осуществляются при спокойном дыхании, активного участия пациента не требуется. Однако остается много неизученных и спорных вопросов, касающихся интерпретации результатов ИОМ. Целью данного исследования явилось изучение возможности ИОМ при диагностике обструкции дыхательных путей легкой степени выраженности. Материалы и методы. Обследованы пациенты (n = 87) с разнообразной бронхолегочной патологией, при этом выявлены вентиляционные нарушения обструктивного типа легкой степени (n = 50). В группе сравнения (n = 37) нарушений по данным спирометрии, бодиплетизмографии и диффузионного теста не отмечено. Результаты. У больных с легкой степенью бронхиальной обструкции, установленной по данным спирометрии, наблюдалось патологическое увеличение частотной зависимости резистивного компонента дыхательного импеданса (Rrs) при частоте осцилляций 5 и 20 Гц (как относительной (Rrs5–Rrs20) / Rrs20, так и абсолютной (Rrs5–Rrs20)), смещение резонансной частоты (fres) в область высоких частот, увеличение площади реактанса (АХ) и экспираторное ограничение потока (DXrs5) при сохранении в пределах нормальных значений Rrs5, Rrs20 и реактивного сопротивления (Xrs5). Заключение. Показано, что при использовании базовых параметров Rrs5 и Xrs5 обструкция легкой степени выраженности, установленная при помощи традиционных функциональных методов, наблюдалась только в 32 % случаев. АХ явился более информативным методом, поскольку изменялся значительно чаще – его увеличение зарегистрировано у 64 % пациентов. Выраженность обструктивных нарушений по данным ИОМ не всегда совпадало с выраженностью нарушений, определяемых при помощи спирометрии

25th Annual Computational Neuroscience Meeting: CNS-2016

Abstracts of the 25th Annual Computational Neuroscience Meeting: CNS-2016 Seogwipo City, Jeju-do, South Korea. 2–7 July 201