α\alpha-Particle Spectrum in the Reaction p+11^{11}B→α+8Be∗→3α\to \alpha + ^8Be^*\to 3\alpha

Using a simple phenomenological parametrization of the reaction amplitude we calculated $\alpha$-particle spectrum in the reaction p+$^{11}$B$\to \alpha + ^8Be^*\to 3\alpha$ at the resonance proton energy 675 KeV. The parametrization includes Breit-Wigner factor with an energy dependent width for intermediate $^8Be^*$ state and the Coulomb and the centrifugal factors in $\alpha$-particle emission vertexes. The shape of the spectrum consists of a well defined peak corresponding to emission of the primary $\alpha$ and a flat shoulder going down to very low energy. We found that below 1.5 MeV there are 17.5% of $\alpha$'s and below 1 MeV there are 11% of them.Comment: 6 pages, 3 figure

Alpha Channeling in a Rotating Plasma

The wave-particle alpha-channeling effect is generalized to include rotating plasma. Specifically, radio frequency waves can resonate with alpha particles in a mirror machine with ExB rotation to diffuse the alpha particles along constrained paths in phase space. Of major interest is that the alpha-particle energy, in addition to amplifying the RF waves, can directly enhance the rotation energy which in turn provides additional plasma confinement in centrifugal fusion reactors. An ancillary benefit is the rapid removal of alpha particles, which increases the fusion reactivity.Comment: 4 pages and 3 figure

Status of the T20 experiment at VEPP–3

Using a gaseous polarized deuterium and the 2 GeV electron beam at 2 GeV beam energy the tensor analyzing power, T20, for the NN potential will be measured with the elastic d↘(e,e) reaction at VEPP‐3, Novosibirsk. A description and progress report of the experiment is given. (AIP)Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87524/2/530_1.pd

Electron scattering from polarized deuterium at VEPP‐3

The status, results, and future plans for the experiment measuring the tensor analyzing power of the deuteron using a tensor‐polarized internal target at the VEPP‐3 electron storage ring in Novosibirsk are presented. © 1995 American Institute of Physics.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87517/2/713_1.pd

The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation

Purpose: In children, data on the combined impact of age, genotype, and disease severity on tacrolimus (TAC) disposition are scarce. The aim of this study was to evaluate the effect of these covariates on tacrolimus dose requirements in the immediate post-transplant period in pediatric kidney and liver recipients. Methods: Data were retrospectively collected describing tacrolimus disposition, age, CYP3A5 and ABCB1 genotype, and pediatric risk of mortality (PRISM) scores for up to 14 days post-transplant in children receiving liver and renal transplants. Initial TAC dosing was equal in all patients and adjusted using therapeutic drug monitoring. We determined the relationship between covariates and tacrolimus disposition. Results: Forty-eight kidney and 42 liver transplant recipients (median ages 11.5 and 1.5 years, ranges 1.5-17.7 and 0.05-14.8 years, respectively) received TAC post-transplant. In both transplant groups, younger children (<5 years) needed higher TAC doses than older children [kidney: 0.15 (0.07-0.35) vs. 0.09 (0.02-0.20) mg/kg/12h, p = 0.046, liver: 0.12 (0.04-0.32) vs. 0.09 (0.01-0.18) mg/kg/12h, p