37 research outputs found
ΠΠ΅ΡΡΠΊΠ°Ρ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½Π°Ρ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΡ Π² ΠΠΎΡΠΊΠ²Π΅: ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΠΈ ΠΈΡ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅
Based on statistical data, a comparative analysis of infectious morbidity and mortality in Moscow in 2015 and 2014 revealed a whole, the decline in these indicators. Made significant progress in reducing infectious morbidity in Moscow due to the vaccination of children, including β increased regional calendar of preventive vaccinations. However, analysis of the work of medical institutions indicates the feasibility of the development and introduction of technologies of management of patients with post-infectious syndromes, as well as improving the health care system for children with infectious diseases based on a multidisciplinary approach in close cooperation infectious disease and pediatricians of different specialties. To solve these problems is proposed a plan to improve the effectiveness of children's infectious diseases services relating to the reorganization of hospital beds and outpatient care, ensure the continuity of the different health facilities, implementation of modern methods of etiological diagnosis of infections, the organization of continuous vocational training of paediatricians in Moscow on a specialty Β«Infectious diseasesΒ».ΠΠ° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π΄Π°Π½Π½ΡΡ
ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΠΎΠΉ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΠΈ ΠΈ Π»Π΅ΡΠ°Π»ΡΠ½ΠΎΡΡΠΈ Π² ΠΠΎΡΠΊΠ²Π΅ Π·Π° 2015 ΠΈ 2014 Π³Π³., Π²ΡΡΠ²ΠΈΠ²ΡΠΈΠΉ, Π² ΡΠ΅Π»ΠΎΠΌ, ΡΠ΅Π½Π΄Π΅Π½ΡΠΈΡ ΠΊ ΡΠΎΠΊΡΠ°ΡΠ΅Π½ΠΈΡ ΡΡΠΈΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ. ΠΠΎΡΡΠΈΠ³Π½ΡΡΡ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠ΅ ΡΡΠΏΠ΅Ρ
ΠΈ Π² ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠΈ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΠΎΠΉ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΠΈ Ρ Π΄Π΅ΡΠ΅ΠΉ ΠΠΎΡΠΊΠ²Ρ Π·Π° ΡΡΠ΅Ρ Π²Π°ΠΊΡΠΈΠ½ΠΎΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠΈ, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ β ΡΠ°ΡΡΠΈΡΠ΅Π½ΠΈΡ ΡΠ΅Π³ΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°Π»Π΅Π½Π΄Π°ΡΡ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΈΠ²ΠΈΠ²ΠΎΠΊ. ΠΠΌΠ΅ΡΡΠ΅ Ρ ΡΠ΅ΠΌ, Π°Π½Π°Π»ΠΈΠ· ΡΠ°Π±ΠΎΡΡ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΡΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ ΡΠΊΠ°Π·ΡΠ²Π°Π΅Ρ Π½Π° ΡΠ΅Π»Π΅ΡΠΎΠΎΠ±ΡΠ°Π·Π½ΠΎΡΡΡ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ ΠΈ Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΡ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π²Π΅Π΄Π΅Π½ΠΈΡ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΏΠΎΡΡΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΡΠΌΠΈ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ°ΠΌΠΈ, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠΎΠ²Π΅ΡΡΠ΅Π½ΡΡΠ²ΠΎΠ²Π°Π½ΠΈΡ ΡΠΈΡΡΠ΅ΠΌΡ ΠΎΠΊΠ°Π·Π°Π½ΠΈΡ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΠΏΠΎΠΌΠΎΡΠΈ Π΄Π΅ΡΡΠΌ Ρ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΡΠΌΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡΠΌΠΈ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΠΌΠ΅ΠΆΠ΄ΠΈΡΡΠΈΠΏΠ»ΠΈΠ½Π°ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΏΡΠΈ ΡΠ΅ΡΠ½ΠΎΠΌ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΠΈ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½ΠΈΡΡΠΎΠ² ΠΈ ΠΏΠ΅Π΄ΠΈΠ°ΡΡΠΎΠ² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ. ΠΠ»Ρ ΡΠ΅ΡΠ΅Π½ΠΈΡ ΡΡΠΈΡ
Π·Π°Π΄Π°Ρ ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½ ΠΏΠ»Π°Π½ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π΄Π΅ΡΡΠΊΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ»ΡΠΆΠ±Ρ, ΠΊΠ°ΡΠ°ΡΡΠΈΠΉΡΡ ΡΠ΅ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ ΠΊΠΎΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΠΎΠ½Π΄Π° ΠΈ Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΠΉ ΠΏΠΎΠΌΠΎΡΠΈ, ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΡΠ΅Π΅ΠΌΡΡΠ²Π΅Π½Π½ΠΎΡΡΠΈ ΡΠ°Π·Π½ΡΡ
ΠΠΠ£, Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΡ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΡΡΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ, ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ Π½Π΅ΠΏΡΠ΅ΡΡΠ²Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ Π²ΡΠ°ΡΠ΅ΠΉ-ΠΏΠ΅Π΄ΠΈΠ°ΡΡΠΎΠ² ΠΠΎΡΠΊΠ²Ρ ΠΏΠΎ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠΈ Β«ΠΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΡΠ΅ Π±ΠΎΠ»Π΅Π·Π½ΠΈΒ»
ΠΡΠ½ΠΎΠ²ΠΎΠΏΠΎΠ»Π°Π³Π°ΡΡΠ΅Π΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎΠ½ΡΡΠΈΠΉ Β«Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΡΒ» ΠΈ Β«Π½Π΅Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΡΒ» Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ ΠΎΡΠ΅Π½ΠΊΠ΅ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΌΡΡΠ΅ΡΠ½ΠΎΠΉ Π΄ΠΈΡΡΡΠΎΡΠΈΠ΅ΠΉ ΠΡΡΠ΅Π½Π½Π°
Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease due to a mutation in the gene encoding dystrophin synthesis. In patients, muscle damage and atrophy progresses, the ability to move independently decreases as well as respiratory and cardiac functions. At various stages of the disease, different methods of care and treatment of patients with DMD are used. The clinical effect of new methods of DMD target therapy may depend on the stage of development of the disease (ambulatory or nonβambulatory). To date, there are no unified criteria for assessing the status of a patient in terms ambulatory. In clinical trials and real clinical practice, different approaches are used to assess the patientβs status. However, the conclusion about the functional capabilities is critical for patients with DMD as approaches in management of patients in ambulatory and nonβambulatory stages differ significantly. This necessitates expert consensus to achieve consistency and avoid any of discrepancies on that issue.The paper reviews the available published data on the concepts of βambulatoryβ and βnonβambulatoryβ used in clinical trials, real clinical practice, international standards and recommendations. As a conclusion of this analysis, it is proposed in real clinical practice to interpret βambulationβ in DMD patients as ability to walk without the use of assistive devices and without specifying the distance and time, and βnonβambulationβ as condition in which the patient is forced to constantly use a wheelchair both indoors and outdoors.ΠΡΡΠ΅ΡΠ½Π°Ρ Π΄ΠΈΡΡΡΠΎΡΠΈΡ ΠΡΡΠ΅Π½Π½Π° (ΠΠΠ) β ΡΠ°ΡΠ°Π»ΡΠ½ΠΎΠ΅ Π½Π΅ΡΠ²Π½ΠΎβΠΌΡΡΠ΅ΡΠ½ΠΎΠ΅ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠ΅, ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π½ΠΎΠ΅ ΠΌΡΡΠ°ΡΠΈΠ΅ΠΉ Π³Π΅Π½Π°, ΠΊΠΎΠ΄ΠΈΡΡΡΡΠ΅Π³ΠΎ Π±Π΅Π»ΠΎΠΊ Π΄ΠΈΡΡΡΠΎΡΠΈΠ½. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅Π³ΠΎΡΡ ΠΈ ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΡΡΡΠ΅Π³ΠΎ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡ ΠΈ Π°ΡΡΠΎΡΠΈΠΈ ΠΌΡΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΡ ΡΠ΅ΡΡΡΡ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡ ΠΊ ΡΠ°ΠΌΠΎΡΡΠΎΡΡΠ΅Π»ΡΠ½ΠΎΠΌΡ ΠΏΠ΅ΡΠ΅Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΡ, Ρ Π½ΠΈΡ
ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΡΡ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΡΠ΅ ΠΈ ΠΊΠ°ΡΠ΄ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ. ΠΠ° ΡΠ°Π·Π½ΡΡ
ΡΡΠ°Π΄ΠΈΡΡ
ΠΠΠ ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΡΡΡΡ ΡΠ°Π·Π½ΡΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ Π²Π΅Π΄Π΅Π½ΠΈΡ. ΠΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΡΡΠ΅ΠΊΡ Π½ΠΎΠ²ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΡΠ°ΡΠ³Π΅ΡΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΠΠ ΠΌΠΎΠΆΠ΅Ρ Π·Π°Π²ΠΈΡΠ΅ΡΡ ΠΎΡ ΡΡΠ°Π΄ΠΈΠΈ Π±ΠΎΠ»Π΅Π·Π½ΠΈ Π½Π° ΠΌΠΎΠΌΠ΅Π½Ρ Π½Π°Π·Π½Π°ΡΠ΅Π½ΠΈΡ Π»Π΅ΡΠ΅Π½ΠΈΡ: Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΠΉ, ΠΊΠΎΠ³Π΄Π° ΠΏΠ°ΡΠΈΠ΅Π½Ρ Ρ
ΠΎΠ΄ΠΈΡ ΡΠ°ΠΌΠΎΡΡΠΎΡΡΠ΅Π»ΡΠ½ΠΎ, ΠΈΠ»ΠΈ Π½Π΅Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΠΉ, ΠΊΠΎΠ³Π΄Π° ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡ ΠΊ ΡΠ°ΠΌΠΎΡΡΠΎΡΡΠ΅Π»ΡΠ½ΠΎΠΉ Ρ
ΠΎΠ΄ΡΠ±Π΅ ΡΡΡΠ°ΡΠ΅Π½Π°. Π‘Π΅Π³ΠΎΠ΄Π½Ρ Π½Π΅Ρ Π΅Π΄ΠΈΠ½ΡΡ
ΠΊΡΠΈΡΠ΅ΡΠΈΠ΅Π² ΡΡΠ°ΡΡΡΠ° ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° Ρ ΡΠΎΡΠΊΠΈ Π·ΡΠ΅Π½ΠΈΡ Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΠΈ, Π° Π² ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΡ
ΠΈ ΡΠ΅Π°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠ°ΠΊΡΠΈΠΊΠ΅ ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΡΡΡΡ ΡΠ°Π·Π½ΡΠ΅ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Ρ ΠΊ Π΅Π΅ ΠΎΡΠ΅Π½ΠΊΠ΅. Π’Π΅ΠΌ Π½Π΅ ΠΌΠ΅Π½Π΅Π΅ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΏΠΎΠ½ΡΡΠΈΠΉ Β«Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΡΒ» ΠΈ Β«Π½Π΅Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΡΒ» ΠΊΡΠΈΡΠΈΡΠ½ΠΎ Π΄Π»Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΠΠ, ΡΠ°ΠΊ ΠΊΠ°ΠΊ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Ρ ΠΊ Π²Π΅Π΄Π΅Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π² Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΠΉ ΠΈ Π½Π΅Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΠΉ ΡΡΠ°Π΄ΠΈΠΈ Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΡΠ°Π·Π»ΠΈΡΠ½Ρ. Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΠΎΠ±Π·ΠΎΡ, ΡΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ ΠΈ Π°Π½Π°Π»ΠΈΠ· ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠΉ Β«Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΡΒ» ΠΈ Β«Π½Π΅Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΡΒ», ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½Π½ΡΡ
Π² ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΡ
, ΡΠ΅Π°Π»ΡΠ½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΠΏΡΠ°ΠΊΡΠΈΠΊΠ΅, ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΡ
ΡΡΠ°Π½Π΄Π°ΡΡΠ°Ρ
ΠΈ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΡΡ
.ΠΠΎ ΠΈΡΠΎΠ³Π°ΠΌ Π°Π½Π°Π»ΠΈΠ·Π° ΠΏΡΠ΅Π΄Π»Π°Π³Π°Π΅ΡΡΡ Π² ΡΠ΅Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΡΠ°ΠΊΡΠΈΠΊΠ΅ ΡΡΠ°ΠΊΡΠΎΠ²Π°ΡΡ Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΡ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΠΠ ΠΊΠ°ΠΊ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡ Ρ
ΠΎΠ΄ΠΈΡΡ Π±Π΅Π· ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π²ΡΠΏΠΎΠΌΠΎΠ³Π°ΡΠ΅Π»ΡΠ½ΡΡ
ΡΡΠ΅Π΄ΡΡΠ² ΠΈ Π±Π΅Π· ΡΠΊΠ°Π·Π°Π½ΠΈΡ Π΄ΠΈΡΡΠ°Π½ΡΠΈΠΈ ΠΈ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ, Π° ΠΏΠΎΡΠ΅ΡΠ΅ΠΉ Π°ΠΌΠ±ΡΠ»Π°ΡΠΎΡΠ½ΠΎΡΡΠΈ ΡΡΠΈΡΠ°ΡΡ ΡΠΎΡΡΠΎΡΠ½ΠΈΠ΅, ΠΏΡΠΈ ΠΊΠΎΡΠΎΡΠΎΠΌ ΠΏΠ°ΡΠΈΠ΅Π½Ρ Π²ΡΠ½ΡΠΆΠ΄Π΅Π½ ΠΏΠΎΡΡΠΎΡΠ½Π½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡ ΠΈΠ½Π²Π°Π»ΠΈΠ΄Π½ΠΎΠ΅ ΠΊΡΠ΅ΡΠ»ΠΎ Π΄Π»Ρ ΠΏΠ΅ΡΠ΅Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΡ ΠΊΠ°ΠΊ Π²Π½Π΅ Π΄ΠΎΠΌΠ°, ΡΠ°ΠΊ ΠΈ Π² Π΄ΠΎΠΌΠ°ΡΠ½ΠΈΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
Surface-modified polyacrylonitrile nanofibers as supports
Polyacrylonitrile nanofibers (PAN-nfs) are one of the most studied nanofibres because of their excellent characteristics, such as good mechanical strength, chemical resistance, and good thermal stability. Due to the easy dissolution in polar organic solvents, PAN-nfs are mostly produced via electrospinning technique. The electrospun PAN-nfs surfaces are relatively in-active and hydrophobic, and, therefore, hinder some potential applications; however, chemical surface modification reactions, such as amination, reduction, hydrolysis, and amidoximation, have been carried out on them. These reactions bring about functional groups, such as amine, hydroxyl, carboxylic, imine etc, to the surface PAN-nfs and invariably make their surfaces active and hydrophilic. The surface-modified PAN-nfs have been used as supports for organic compounds, enzymes, and antibodies in biological studies. They have also been used for immobilization of various organic ligands for adsorption of metal ions in water. Furthermore, because of their ability to complex metal ions, several surface-modified PAN-nfs have also been used as supports for transition metal catalysts in Fentonβs chemistry.IS
Part 1: production of a modified PAN fibrous catalyst and its optimisation towards the decomposition of hydrogen peroxide
This paper describes the novel and innovative use of a mixture of hydrazine and hydroxylamine to prepare one of the first solid state Fentonβs catalysts where the active site does not leach out and is therefore reusable enabling industrial take-up. It resulted in an ongoing series of papers, 4 grants totalling Β£2million, and the award or filing of 5 patents. The catalyst is in field trials with Severn Trent Water for the removal of microcontaminats to meet new EU legislation. A similar process applied to low-value wool fibres (as patented by KDH) is likely to result in improved rural sustainability
Investigation of the mechanical and physico-chemical properties of a modified PANΒ fibrous catalyst
This paper was the first confirmation that the metal catalyst was located on the exterior surface of the fibre and the first to obtain an understanding of the number and nature of atoms around the active site by an EXAFS study at the international Synchrotron Source at Daresbury. Characterisation of the mechanical strength of the catalyst showed that it was good enough for industrial applications as detailed above
EFFICIENCY EVALUATION OF ENTERPRISE INFORMATION SYSTEMS WITH NON-UNIFORM LOAD
The paper deals with the problem of characteristics evaluation for enterprise information systems at the design stage. In the design of ERP-systems the most interest characteristic is not the average time, but the probability of timely delivery of different type messages (for example, command, service, multimedia, files, etc.) from the sender to the recipient. In addition,the possibility of using the priority information management built on the basis of service disciplines of general form with mixed priorities needs to be considered. An open queuing network with non-uniform data flow is used for solution of this problem. The method for calculation of information systems characteristics is proposed based on the decomposition of the network model. The end results obtained with this approach and by means of priority management are approximate because different classes of message streams at the output and input nodes of the computer system differ from the simple ones. However, result errors of the proposed analytical method are in acceptable limits for engineering calculations as it was shown by simulation in a wide range of parameters corresponding to real systems. Obtained results are usable for optimization problem solution of data transmission networks in modern information systems, involving routing algorithm definition and priorities specification for different classes of messages to provide given delivery time
THE ANALYSIS OF SUCCESS MOTIVATION AND FAILURES AVOIDANCE OF THE FIRST-YEAR STUDENTS OF ECONOMICS IN KRASNOYARSK
Π’Π΅ΠΊΡΡ ΡΡΠ°ΡΡΠΈ Π½Π΅ ΠΏΡΠ±Π»ΠΈΠΊΡΠ΅ΡΡΡ Π² ΠΎΡΠΊΡΡΡΠΎΠΌ Π΄ΠΎΡΡΡΠΏΠ΅ Π² ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠΈ Ρ ΠΏΠΎΠ»ΠΈΡΠΈΠΊΠΎΠΉ ΠΆΡΡΠ½Π°Π»Π°.In the course of education a significant role is played by motivation of students. The study of academic motivation is one of the fundamental problems in pedagogics and psychology, since an efficient interaction between teachers and students is possible within understanding of their motivation. To teach in todayβs environment it is necessary to be able to interpret such pshyco-pedagogical characteristics of a person as motivation, independent behavior, active performance and ability to reach oneβs goals.
To assess the motivation of the first-year students of economics in Krasnoyarsk we have used A. Mekhrabianβs inventory consisted of two forms: for males and females.
Within the research, to identify relation between the motivation and performance of the students we have estimated Spearmanβs rank correlation.
The current research results in the fact that the majority of the first-year respondents are mainly willing to avoid failures. The distribution of points within the groups is close to a normal distribution. The indicators of motivation and academic performance of the students are correlated by the tie β average in size and straight in direction.
To increase the number of students encouraged to succeed it is necessary to implement innovative teaching methods. The education techniques should be primarily aimed at the development of studentβs cognitive interest in the process of education. The process of teaching should also be modernized with the active learning methods improving R&D work and solving the problems related to their future profession. It is also necessary to encourage the students for a successful academic and scientific life in the university starting from the very beginning
Implementation of the Model of Noosphere-Aesthetic Education of Primary School Students by Means of Regional Culture
The relevance of the problem of noosphere-aesthetic education of primary school students is due to the need for their entry into noosphere-cultural space of the region which affects the formation of humanistic attitude of students to all life on the earth, their native nature and culture; insufficient theoretical and practical development of the model for the implementation of this phenomenon.The purpose of the article is theoretical substantiation, development and implementation of the model of noosphere-aesthetic education of primary school students by means of regional culture.The leading method of research is modeling which allows to create and implement an integral system of noosphere-aesthetic education of primary school students by means of regional culture.On the basis of cultural and environmental approaches we have defined the content of the concepts "noosphere-aesthetic education of primary school students", βregional culture" and proved the effectiveness of the model for implementing this approach. In this article from the standpoint of cultural and environmental approaches the concept of "noosphere-aesthetic education of primary school students" is clarified, the effectiveness of the implementation model of this phenomenon by means of regional culture is proved, prospects of using its building blocks: target, structural, diagnostic, technological and effective in the education system are substantiated.The results of the research presented in the article and statistical processing of experimental data using R.Fisher's angular coefficient of transformation proved the effectiveness of proposed model in educational process.Practical significance of the study is that diagnostic techniques, program, process unit of the model presented in the article contribute to more efficient noosphere education of primary school students and can be used by teachers of higher school, primary school teachers and educators in their activities
Quantum-chemical investigation of mechanisms of reactions of nucleophilic addition to acetylene. 7. Evaluation of possible interactions in C2H2/MOH/DMSO system
FATAL QUARTET OR QUINTET?
Correction of potential risk factors is essential for effective therapy for cardiovascular diseases. This clinical case demonstrates negativeΒ impact of non-corrected risk factors β obstructive sleep apnea β in occurrence and further progression of cardiovascular disease.</p