Letter to the editor. Discussion of the article by A.A. Zarubin, E.S. Filippov, A.S. Vanyarkina, O.G. Ivanova, A.A. Shishkina “Comparison of Uncontrolled and Device-Induced Therapeutic Hypothermia in Newborn Infants with Hypoxic Ischemic Encephalopathy”, published in Acta biomedica scientifica. 2021; 6(1): 88-93. doi: 10.29413/ABS.2021-6.1.13

The article presents a discussion of the study results of the effectiveness of treatment of newborns infants with hypoxic ischemic encephalopathy using device-induced therapeutic hypothermia which were obtained by a group of researchers (Zarubin A.A. et al.) in comparison with the results of Russian and foreign researchers

GORHAM-STOUT SYNDROME: DESCRIPTION OF A CASE

The paper describes a case of Gorham-Stout syndrome, a rare condition, which is accompanied by massive osteolysis of different portions of bone tissue. It reviews the data available in the literature on this problem. Idiopathic osteolysis concurrent with chylothorax has a poor prognosis. The syndrome can be treated only with calcitonins or bisphosphonates

Massive osteolysis - gorham-stout syndrome

The paper provides a detailed description of the two cases of one of the rarest diseases - Gorham-Stout syndrome. This syndrome is accompanied by the massive osteolysis of various sites of a bone tissue. The literary review is done. The isolated osteolysis of the separate bone parts is a non-malignant process, and it goes without abnormalities of its functions. The combination of osteolysis with chylothorax is an unfavorable process. The treatment of this disease is possible only by calcitonin or bisphosphonates

Evaluation of low cycle fatigue based on the use of Coffin-Manson dependence under zero-to-“soft” loading cycle

To calculate the durability of gas turbine engine parts damaged by low-cycle fatigue (LCF), according to the Structural codes of turbine engine strength it is necessary to test specimens cut from respective parts (or test coupons) under hard loading. Hard here means there is a fixed strain cycle. The tests are conducted with different asymmetry coefficients of the strain cycle and with different exposure time at the maximum cycle strain (to take into account the effect of creep at high temperatures). The tests carried out are to provide sufficient statistics to ensure the reliability of the calculation. We suggest a method of assessing the durability of gas turbine engine parts based on testing standard specimens at zero-to-soft loading cycle using modified Manson-Coffins equation. The results of the work confirm the possibility of achieving the required adequacy of assessing the durability of parts damaged by the LCF mechanism with the use of a modified Manson-Coffin equation. Some recommendations concerning its application are given

Medical and social characteristics of families and psychological characteristics of mothers of children born with a body weight of less than 1500 g

In order to study the medical and social characteristics of families, an analysis of the biological and social history of mothers and fathers of children born with a body weight less than 1500 was carried out. To identify the psychological characteristics, mothers were tested.It has been established that the social characteristics of the families of children born with a body weight of less than 1500 g was favorable – most families were two-parent, had satisfactory living conditions, mothers and fathers of these children were working and had education not lower than secondary special. The majority of fathers (80%) considered themselves healthy, the state of health of mothers was characterized by a high frequency of somatic pathology, only 27% of women were healthy. The majority of fathers and mothers noted the impact of occupational hazards, while the mothers’ adverse factors were mainly associated with intellectual activity, and the fathers – with physical labor. Half of mothers and 70% of fathers belonged to the age group of 30 years and older. Despite the favorable characteristics of reproductive behavior at the stage of pregravid preparation and in the first trimester of pregnancy, mothers who gave birth to children weighing less than 1500 g were characterized by an unfavorable obstetric gynecological history and a high incidence of gynecological pathology. Psychological features of mothers consisted in a high frequency of accentuation of hyperthymic character traits, a desire to emphasize determination and masculinity, anxiety, impulsivity, which may indicate a compensatory reaction to a stressful situation – the birth of a premature baby. This is also indicated by the high frequency of psychosomatic (45.9%) and authoritarian (29.5%) types of attitude to the problems of the child. In this regard, only 62.2% of mothers established optimal emotional contact with the child by the end of the neonatal period. The revealed psychological characteristics of mothers require early psychological and psychotherapeutic correction to successfully overcome the stress of giving birth to a premature baby and consolidate all the efforts of a woman for habilitation