1,017 research outputs found
ΠΡΠ΅Π½ΠΊΠ° ΠΌΠΎΡΡΠΎΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΏΠ°ΡΠΈΠ΅ΡΠ°Π»ΡΠ½ΠΎΠΉ Π±ΡΡΡΠΈΠ½Ρ Π΄Π»Ρ ΠΏΡΠΎΠ³Π½ΠΎΠ·Π° ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΎΡΡΡΠΎΠ³ΠΎ ΡΠ°Π·Π»ΠΈΡΠΎΠ³ΠΎ ΠΏΠ΅ΡΠΈΡΠΎΠ½ΠΈΡΠ°
Π¦Π΅Π»Ρ. Π Π°Π·ΡΠ°Π±ΠΎΡΠ°ΡΡ ΠΈ ΠΎΡΠ΅Π½ΠΈΡΡ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π½Π°ΡΠΈΠΌΡΠ΅ ΠΊΡΠΈΡΠ΅ΡΠΈΠΈ ΡΠ΅ΡΠ΅Π½ΠΈΡ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° Π² Π±ΡΡΡΠ½ΠΎΠΉ ΠΏΠΎΠ»ΠΎΡΡΠΈ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΎΡΡΡΡΠΌ ΡΠ°Π·Π»ΠΈΡΡΠΌ ΠΏΠ΅ΡΠΈΡΠΎΠ½ΠΈΡΠΎΠΌ (ΠΠ Π).
ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ Π΄Π°Π½Π½ΡΠ΅ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ Π±ΠΈΠΎΠΏΡΠ°ΡΠΎΠ² ΠΏΠ°ΡΠΈΠ΅ΡΠ°Π»ΡΠ½ΠΎΠΉ Π±ΡΡΡΠΈΠ½Ρ Ρ 55 Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΠ Π ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠΉ ΡΡΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ. ΠΠ·ΡΡΠ΅Π½Ρ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ Π½Π΅ΠΉΡΡΠΎΡΠΈΠ»ΡΠ½ΠΎ-ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠ½ΠΎΡΠ΄Π΅ΡΠ½ΡΡ
Π»Π΅ΠΉΠΊΠΎΡΠΈΡΠΎΠ² (ΠΠΠ―Π), ΠΌΠ°ΠΊΡΠΎΡΠ°Π³ΠΎΠ², Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ², ΡΠΈΠ±ΡΠΎΠ±Π»Π°ΡΡΠΎΠ², ΠΎΡΠ°Π³ΠΎΠ² Π½Π΅ΠΊΡΠΎΠ·Π°, ΠΎΡΡΠ°ΠΆΠ°ΡΡΠΈΠ΅ ΡΡΠΆΠ΅ΡΡΡ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° Π² ΠΏΠ°ΡΠΈΠ΅ΡΠ°Π»ΡΠ½ΠΎΠΉ Π±ΡΡΡΠΈΠ½Π΅ Π΄ΠΎ ΠΈ ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ.
Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠ½Π°Π»ΠΈΠ· Π΄Π°Π½Π½ΡΡ
ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ Π±ΠΈΠΎΠΏΡΠ°ΡΠΎΠ² ΠΏΠ°ΡΠΈΠ΅ΡΠ°Π»ΡΠ½ΠΎΠΉ Π±ΡΡΡΠΈΠ½Ρ ΠΏΠΎΠΊΠ°Π·Π°Π», ΡΡΠΎ ΠΏΡΠΈ ΡΠ΄Π΅Π»ΡΠ½ΠΎΠΌ ΠΎΠ±ΡΠ΅ΠΌΠ΅ ΠΠΠ―Π 0,1314 Β± 0,0546, Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ² 0,0145 Β± 0,0038, ΠΌΠ°ΠΊΡΠΎΡΠ°Π³ΠΎΠ² 0,0046 Β± 0,0013, ΡΠΈΠ±ΡΠΎΠ±Π»Π°ΡΡΠΎΠ² 0,1238 Β± 0,0203, ΠΎΡΠ°Π³ΠΎΠ² Π½Π΅ΠΊΡΠΎΠ·Π° 0,0053 Β± 0,0016 ΠΏΡΠΎΠ³Π½ΠΎΠ· Π±ΡΠ» ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎ Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΡΠΌ. ΠΡΠ»ΠΈ ΡΠ΄Π΅Π»ΡΠ½ΡΠΉ ΠΎΠ±ΡΠ΅ΠΌ ΠΠΠ―Π Π±ΡΠ» ΡΠ°Π²Π΅Π½ ΠΈΠ»ΠΈ Π²ΡΡΠ΅ 0,3128 Β± 0,0334, Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ² - 0,0202 Β± 0,0053, ΠΌΠ°ΠΊΡΠΎΡΠ°Π³ΠΎΠ² - 0,0049 Β± 0,0016, ΡΠΈΠ±ΡΠΎΠ±Π»Π°ΡΡΠΎΠ² - 0,1192 Β± 0,0077, ΠΎΡΠ°Π³ΠΎΠ² Π½Π΅ΠΊΡΠΎΠ·Π° - 0,0173 Β± 0,0046, ΠΏΡΠΎΠ³Π½ΠΎΠ· Π±ΡΠ» Π½Π΅Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΡΠΌ. ΠΠ΅ΡΠ°Π»ΡΠ½ΠΎΡΡΡ ΡΠΎΡΡΠ°Π²ΠΈΠ»Π° 16,3%.
ΠΡΠ²ΠΎΠ΄Ρ. ΠΠΎΡΡΠΎΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΠΏΠ°ΡΠΈΠ΅ΡΠ°Π»ΡΠ½ΠΎΠΉ Π±ΡΡΡΠΈΠ½Ρ, ΡΡΠ°Π²Π½ΠΈΠ²Π°Π΅ΠΌΡΠ΅ Ρ ΡΡΠΆΠ΅ΡΡΡΡ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π±ΠΎΠ»ΡΠ½ΡΡ
, ΠΎΡΠ΅Π½Π΅Π½Π½ΠΎΠΉ ΠΏΠΎ ΡΠΊΠ°Π»Π΅ SAPS (Simplified acute physiology score - ΡΠΏΡΠΎΡΠ΅Π½Π½Π°Ρ ΡΠΊΠ°Π»Π° ΠΎΡΠ΅Π½ΠΊΠΈ ΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΡΡΡΡΠΎΠΉΡΡΠ²), ΠΎΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΎΡΡΠ°ΠΆΠ°ΡΡ ΡΡΠΆΠ΅ΡΡΡ ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΠ Π, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡ ΠΎΡΠ΅Π½ΠΈΡΡ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΡ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° Π² Π±ΡΡΡΠ½ΠΎΠΉ ΠΏΠΎΠ»ΠΎΡΡΠΈ ΠΈ ΡΠ»ΡΠΆΠ°Ρ ΠΊΡΠΈΡΠ΅ΡΠΈΡΠΌΠΈ ΠΏΡΠΎΠ³Π½ΠΎΠ·Π° ΡΠ΅ΡΠ΅Π½ΠΈΡ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ, ΡΡΠΎ Π΄Π°Π΅Ρ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΊ Π²ΡΠ±ΠΎΡΡ ΡΠ°ΠΊΡΠΈΠΊΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ
The Maupertuis principle and canonical transformations of the extended phase space
We discuss some special classes of canonical transformations of the extended
phase space, which relate integrable systems with a common Lagrangian
submanifold. Various parametric forms of trajectories are associated with
different integrals of motion, Lax equations, separated variables and
action-angles variables. In this review we will discuss namely these induced
transformations instead of the various parametric form of the geometric
objects
THE EGALITARIAN PRINCIPLES OF THE OLD BOHEMIAN STATEHOOD AND THE LEGAL SYSTEM
Purpose: The article is devoted to the study of egalitarian principles of medieval Czech statehood and the legal system.
Methods: The authors pay special attention to the peculiarities of family self-government of the Czech communities, the institution of hazing in land law and the mechanism of reconciliation as an alternative to the death penalty.
Findings: The paper proves that tribal remnants of the customary law of the ancient Czech people in the medieval era contributed to the preservation of egalitarian democratic principles of public administration and justice
Canonical transformations of the extended phase space, Toda lattices and Stackel family of integrable systems
We consider compositions of the transformations of the time variable and
canonical transformations of the other coordinates, which map completely
integrable system into other completely integrable system. Change of the time
gives rise to transformations of the integrals of motion and the Lax pairs,
transformations of the corresponding spectral curves and R-matrices. As an
example, we consider canonical transformations of the extended phase space for
the Toda lattices and the Stackel systems.Comment: LaTeX2e + Amssymb, 22p
A Comprehensive Diagnosis of Components of Pedagogical Studentsβ Research Competency
Introduction. Nowadays, the aspects of development of research competencies in future experts belong to the most relevant topics, which are widely being discussed both in Russian and in foreign scientific community. One of burning issues in this thematic block is diagnosis of such competencies without which their successful development is impossible. Today, we are witnessing the disparity between a large number of the methods presented in scientific sources and technologies of the formation of studentsβ research competency and limitation of its criteria and indicators. Moreover, there is lack of adequate methodological tools to estimate objectively the level and quality of scientific literacy and degree of studentsβ research activity.The aim of the research was to define the content of a comprehensive diagnosis of the components of pedagogical studentsβ research competency and to justify the criteria, indicators and methods of its evaluation. Methodology and research methods. The methods of analysis, synthesis, generalisation and modelling were employed. The systematic approach was applied, taking into account the provisions of plurality, integrity and structurisation. Results and scientific novelty. The authors presented and described the model of formation of pedagogical studentsβ practice-focused research competency. The knowledge-based, value-oriented and practical components of the model are correlated to the methods of psycho-pedagogical monitoring, which are relevant to the content of these components. The complex of particular techniques for comprehensive, precise and complete assessment of future teachersβ research competency is designed. The complexity of measurement tools is provided with homogeneity between a theoretical construct (research competency) and operationalised constructs (psychological phenomena estimated in diagnostic techniques). Cumulative application of the selected diagnostic procedures and techniques allows: objective and subjective indicators of formation of research abilities and skills to be compared; motivation and readiness of students for implementation of independent research activity to be defined, taking into account social and professional contexts of its realisation. Practical significance. The authors of the present publication propose to introduce into practice of the higher school the approaches to contents, structure and organisation of the psychological diagnostics of level of studentsβ research competency, which will give the chance not only to carry out the internal regular and continuous monitoring of formation of one of key characteristics of the identity of the modern expert in educational institutions, but also to optimise the process of multilevel high school preparation, having adjusted work on early identification of its problems and crisis stages to take timely effective correctional measures.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. Π Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠΌ, ΠΊΠ°ΡΠ°ΡΡΠΈΠΌΡΡ ΡΡΠ½ΠΊΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π²ΡΡΡΠ΅ΠΉ ΡΠΊΠΎΠ»Ρ ΡΠ΅ΠΌΠ°ΠΌ, ΡΠΈΡΠΎΠΊΠΎ ΠΎΠ±ΡΡΠΆΠ΄Π°ΡΡΠΈΠΌΡΡ ΠΊΠ°ΠΊ Π² ΡΠΎΡΡΠΈΠΉΡΠΊΠΎΠΌ, ΡΠ°ΠΊ ΠΈ Π² Π·Π°ΡΡΠ±Π΅ΠΆΠ½ΠΎΠΌ Π½Π°ΡΡΠ½ΠΎΠΌ ΡΠΎΠΎΠ±ΡΠ΅ΡΡΠ²Π΅, ΠΎΡΠ½ΠΎΡΡΡΡΡ Π°ΡΠΏΠ΅ΠΊΡΡ ΠΎΡΠ²ΠΎΠ΅Π½ΠΈΡ Π±ΡΠ΄ΡΡΠΈΠΌΠΈ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΡΡΠ°ΠΌΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΈΡ
ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΉ. ΠΠ΄Π½ΠΎΠΉ ΠΈΠ· ΠΎΡΡΡΡΡ
ΠΏΡΠΎΠ±Π»Π΅ΠΌ Π² Π΄Π°Π½Π½ΠΎΠΌ ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΌ Π±Π»ΠΎΠΊΠ΅ ΡΠ²Π»ΡΠ΅ΡΡΡ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ° ΡΠ°ΠΊΠΎΠ³ΠΎ ΡΠΎΠ΄Π° ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΉ, Π±Π΅Π· ΠΊΠΎΡΠΎΡΠΎΠΉ Π½Π΅Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎ ΠΈΡ
ΡΡΠΏΠ΅ΡΠ½ΠΎΠ΅ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅. Π Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ Π½Π°Π±Π»ΡΠ΄Π°Π΅ΡΡΡ Π½Π΅ΡΠΎΡΠ°Π·ΠΌΠ΅ΡΠ½ΠΎΡΡΡ ΠΌΠ΅ΠΆΠ΄Ρ ΠΎΠ³ΡΠΎΠΌΠ½ΡΠΌ ΡΠΈΡΠ»ΠΎΠΌ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΡ
Π² Π½Π°ΡΡΠ½ΡΡ
ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠ°Ρ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΈ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ Ρ ΡΡΡΠ΄Π΅Π½ΡΠΎΠ² ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠ½ΠΎΡΡΠΈ ΠΈ ΠΎΠ³ΡΠ°Π½ΠΈΡΠ΅Π½Π½ΠΎΡΡΡΡ Π΅Π΅ ΠΊΡΠΈΡΠ΅ΡΠΈΠ΅Π² ΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ΠΌ Π°Π΄Π΅ΠΊΠ²Π°ΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°ΡΠΈΡ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠ΅Π³ΠΎ ΠΎΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΎΡΠ΅Π½ΠΈΠ²Π°ΡΡ ΡΡΠΎΠ²Π΅Π½Ρ ΠΈ ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ Π½Π°ΡΡΠ½ΠΎΠΉ Π³ΡΠ°ΠΌΠΎΡΠ½ΠΎΡΡΠΈ ΠΈ ΡΡΠ΅ΠΏΠ΅Π½Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΎΠ±ΡΡΠ°ΡΡΠΈΡ
ΡΡ. Π¦Π΅Π»Ρ ΠΈΠ·Π»ΠΎΠΆΠ΅Π½Π½ΠΎΠΉ Π² ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΈ ΡΠ°Π±ΠΎΡΡ β ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡΡ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ² ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΈ Ρ ΡΡΡΠ΄Π΅Π½ΡΠΎΠ² ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΈΠΉ ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠΈ ΠΈ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°ΡΡ Π²ΡΠ±ΠΎΡ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊ Π΅Π΅ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΡ. ΠΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅, Π² Ρ
ΠΎΠ΄Π΅ ΠΊΠΎΡΠΎΡΠΎΠ³ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈΡΡ ΠΌΠ΅ΡΠΎΠ΄Ρ Π°Π½Π°Π»ΠΈΠ·Π°, ΡΠΈΠ½ΡΠ΅Π·Π°, ΠΎΠ±ΠΎΠ±ΡΠ΅Π½ΠΈΡ ΠΈ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ, Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΎ Ρ ΠΎΠΏΠΎΡΠΎΠΉ Π½Π° ΡΠΈΡΡΠ΅ΠΌΠ½ΡΠΉ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄, Π±Π°Π·ΠΈΡΡΡΡΠΈΠΉΡΡ Π½Π° ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡΡ
ΠΌΠ½ΠΎΠΆΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΡΡΠΈ, ΡΠ΅Π»ΠΎΡΡΠ½ΠΎΡΡΠΈ ΠΈ ΡΡΡΡΠΊΡΡΡΠΈΠ·Π°ΡΠΈΠΈ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ Π½Π°ΡΡΠ½Π°Ρ Π½ΠΎΠ²ΠΈΠ·Π½Π°. ΠΠΏΠΈΡΠ°Π½Π° Π°Π²ΡΠΎΡΡΠΊΠ°Ρ ΠΌΠΎΠ΄Π΅Π»Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠ°ΠΊΡΠΈΠΊΠΎ-ΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΈ ΡΡΡΠ΄Π΅Π½ΡΠΎΠ² ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ. Π‘ΠΎΡΡΠ°Π²Π»ΡΡΡΠΈΠ΅ ΠΌΠΎΠ΄Π΅Π»Ρ Π·Π½Π°Π½ΠΈΠ΅Π²ΡΠΉ, ΡΠ΅Π½Π½ΠΎΡΡΠ½ΡΠΉ ΠΈ ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΡ ΡΠΎΠΎΡΠ½Π΅ΡΠ΅Π½Ρ Ρ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ ΠΏΡΠΈΡ
ΠΎΠ»ΠΎΠ³ΠΎ-ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π°, ΡΠ΅Π»Π΅Π²Π°Π½ΡΠ½ΡΠΌΠΈ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΡΡΠΈΡ
ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ². Π‘ΠΊΠΎΠ½ΡΡΡΡΠΈΡΠΎΠ²Π°Π½ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡ ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊ Π΄Π»Ρ Π²ΡΠ΅ΡΡΠΎΡΠΎΠ½Π½Π΅ΠΉ, ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎ ΡΠΎΡΠ½ΠΎΠΉ ΠΈ ΠΏΠΎΠ»Π½ΠΎΠΉ ΠΎΡΠ΅Π½ΠΊΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΈ Π±ΡΠ΄ΡΡΠΈΡ
ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ². ΠΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΡΡΡ ΠΈΠ·ΠΌΠ΅ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°ΡΠΈΡ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°Π΅ΡΡΡ Π³ΠΎΠΌΠΎΠ³Π΅Π½Π½ΠΎΡΡΡΡ ΠΌΠ΅ΠΆΠ΄Ρ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΎΠΌ (ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠ΅ΠΉ) ΠΈ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌΠΈ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠ°ΠΌΠΈ (ΠΏΡΠΈΡ
ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΡΠ΅Π½ΠΎΠΌΠ΅Π½Π°ΠΌΠΈ, ΠΎΡΠ΅Π½ΠΈΠ²Π°Π΅ΠΌΡΠΌΠΈ Π² Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠ°Ρ
). Π‘ΠΎΠ²ΠΎΠΊΡΠΏΠ½ΠΎΠ΅ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΎΡΠΎΠ±ΡΠ°Π½Π½ΡΡ
Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΎΡΠ΅Π΄ΡΡ ΠΈ ΡΠ΅Ρ
Π½ΠΈΠΊ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΡΠΎΠΏΠΎΡΡΠ°Π²Π»ΡΡΡ ΠΎΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠ΅ ΠΈ ΡΡΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΡΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½Π½ΠΎΡΡΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΈΡ
ΡΠΌΠ΅Π½ΠΈΠΉ, Π½Π°Π²ΡΠΊΠΎΠ² ΠΈ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠ΅ΠΉ; ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡ ΠΌΠΎΡΠΈΠ²Π°ΡΠΈΡ ΠΈ Π³ΠΎΡΠΎΠ²Π½ΠΎΡΡΡ ΡΡΡΠ΄Π΅Π½ΡΠΎΠ² ΠΊ ΠΎΡΡΡΠ΅ΡΡΠ²Π»Π΅Π½ΠΈΡ ΡΠ°ΠΌΠΎΡΡΠΎΡΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ Ρ ΡΡΠ΅ΡΠΎΠΌ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈ ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΠ΅ΠΊΡΡΠΎΠ² Π΅Π΅ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ. ΠΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π·Π½Π°ΡΠΈΠΌΠΎΡΡΡ. ΠΠ½Π΅Π΄ΡΠ΅Π½ΠΈΠ΅ Π² ΠΏΡΠ°ΠΊΡΠΈΠΊΡ Π²ΡΡΡΠ΅ΠΉ ΡΠΊΠΎΠ»Ρ ΠΏΡΠ΅Π΄Π»Π°Π³Π°Π΅ΠΌΡΡ
Π°Π²ΡΠΎΡΠ°ΠΌΠΈ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ΠΎΠ² ΠΊ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ, ΡΡΡΡΠΊΡΡΡΠ΅ ΠΈ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΡΠΈΡ
ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΡΡΠΎΠ²Π½Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΈ ΠΎΠ±ΡΡΠ°ΡΡΠΈΡ
ΡΡ Π΄Π°ΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΡΡ Π² ΡΡΠ΅Π±Π½ΡΡ
Π·Π°Π²Π΅Π΄Π΅Π½ΠΈΡΡ
Π²Π½ΡΡΡΠ΅Π½Π½ΠΈΠΉ ΡΠ΅Π³ΡΠ»ΡΡΠ½ΡΠΉ ΠΏΠΎΠ»Π½ΠΎΡΠ΅Π½Π½ΡΠΉ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³ ΡΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½Π½ΠΎΡΡΠΈ ΠΎΠ΄Π½ΠΎΠΉ ΠΈΠ· ΠΊΠ»ΡΡΠ΅Π²ΡΡ
Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ Π»ΠΈΡΠ½ΠΎΡΡΠΈ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΡΡΠ°, Π½ΠΎ ΠΈ ΠΎΠΏΡΠΈΠΌΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ ΠΏΡΠΎΡΠ΅ΡΡ ΠΌΠ½ΠΎΠ³ΠΎΡΡΠΎΠ²Π½Π΅Π²ΠΎΠΉ Π²ΡΠ·ΠΎΠ²ΡΠΊΠΎΠΉ ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠΈ, Π½Π°Π»Π°Π΄ΠΈΠ² ΡΠ°Π±ΠΎΡΡ ΠΏΠΎ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΠΎΠΌΡ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ Π΅Π³ΠΎ ΠΏΡΠΎΠ±Π»Π΅ΠΌ ΠΈ ΠΊΡΠΈΠ·ΠΈΡΠ½ΡΡ
ΡΡΠ°ΠΏΠΎΠ² Π΄Π»Ρ ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠΈΠ½ΡΡΠΈΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΠΊΠΎΡΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΡΡ
ΠΌΠ΅Ρ.the Russian Foundation for Basic Research, project β18β013β00268 A βFormation of Studentsβ Research Competencies of the System of Multilevel Psycho-Pedagogical Education and Vocational Development of Pedagogical Personnel in Higher Educational InstitutionβΠ Π€Π€Π Π² ΡΠ°ΠΌΠΊΠ°Ρ
Π½Π°ΡΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠ΅ΠΊΡΠ° β18β013β00268 Π Β«Π€ΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΈΡ
ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΉ ΠΎΠ±ΡΡΠ°ΡΡΠΈΡ
ΡΡ Π² ΡΠΈΡΡΠ΅ΠΌΠ΅ ΠΌΠ½ΠΎΠ³ΠΎΡΡΠΎΠ²Π½Π΅Π²ΠΎΠ³ΠΎ ΡΠ½ΠΈΠ²Π΅ΡΡΠΈΡΠ΅ΡΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΈΡ
ΠΎΠ»ΠΎΠ³ΠΎ-ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ ΠΊΠ²Π°Π»ΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΊΠ°Π΄ΡΠΎΠ²
Leonardo da Vinciβs ceativity and attention deficit hyperactivity disorder
The article discusses a correlation between the character and life of Leonardo da Vinci and possible manifestations of his attention deficit disorder
Two-dimensional superintegrable metrics with one linear and one cubic integral
We describe all local Riemannian metrics on surfaces whose geodesic flows are
superintegrable with one integral linear in momenta and one integral cubic in
momenta.
We also show that some of these metrics can be extended to the 2-sphere. This
gives us new examples of Hamiltonian systems on the sphere with integrals of
degree three in momenta, and the first examples of superintegrable metrics of
nonconstant curvature on a closed surfaceComment: 35 page
ΠΡΠΎΠ±Π»Π΅ΠΌΡ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΠ΅Π½ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ΅ΡΠΎΡΠΌΡ Π² Π ΠΎΡΡΠΈΠΈ
Π Π΄Π°Π½Π½ΠΎΠΉ ΡΡΠ°ΡΡΠ΅ ΡΠ°ΡΠΊΡΡΡΠ° ΡΡΡΡ ΠΏΠ΅Π½ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ΅ΡΠΎΡΠΌΡ Π² Π Π€. ΠΠΎΠΊΠ°Π·Π°Π½Ρ Π΅Π΅ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΠΏΡΠ΅ΠΈΠΌΡΡΠ΅ΡΡΠ²Π° ΠΈ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΊΠΈ Π½ΠΎΠ²ΠΎΠ²Π²Π΅Π΄Π΅Π½ΠΈΠΉ
LYMPHOCYTE PHENOTYPE IN PATIENTS WITH SKIN MELANOMA AFTER IMMUNOTHERAPY OF ACTIVATED LYMPHOCYTES
The major medical problem in the treatment of skin melanoma is improvement methods ofΒ treatment, increasing their effectiveness and safety. In this study, adoptive immunotherapy, using lymphocytes activated in vitro, was performed in 15 patients with metastatic melanoma. Evaluated the phenotype of peripheral blood lymphocytes and activation markers (HLA-DR, CD25, CD314, CD38, CD69) before and 3-4 weeks after immunotherapy. It is shown that for these patients is characterized by increasing the number of CD25+ and Treg lymphocytes in the bloodstream, which has not changed after immunotherapy. Adoptive immunotherapy in combination with chemotherapy resulted in a decrease of absolute number of lymphocyte, B- and T-lymphocytes, T helper cells, NKT-cells, CD314+ lymphocytes, CD38+ lymphocytes and immature T-lymphocytes (CD3+CD38+) (Ρ < 0,05). However, there was a positive dynamic to increase the percentage of NK-cells to 32% and CD69+NK-cells to 21% and significant increase in expression of HLA-DR on all lymphocytes (p < 0.05). Adoptive immunotherapy characterized by the absence of side effects and can be recommended as accompanying to basic radiation and chemotherapy
The use of atomic force microscopy in comprehensive assessment of the "mother-placenta-fetus" system in obstetric and endocrine pathology during pregnancy
Our study summarizes the possibilities of using atomic force microscopy for detection of various circulatory disorders and vascular changes at the microscopic level in the uterus (endometrium and myometrium), placenta, and umbilical cord in the main variants of obstetric and endocrine patholo
- β¦