The clinical and neurological, cognitive and anxiety-depressive disorders in patients with chronic brain ischemia

The article is devoted to the study ot the characteristics of clinical-neurological, cognitive and anxiety-depressive disorders in patients with chronic cerebral ischemia of various origins. Presents a comparative analysis of the severity of the disturbed — functions of the brain depending on the stage and etiology of chronic ischemia of the brain.Статья посвящена изучению особенностей клинико-неврологических, когнитивных и тревожно-депрессивных нарушений у больных хронической ишемии мозга различного генеза. Представлен сравнительный анализ выраженности нарренных функций мозга в зависимости от стадии и этиологии хронической ишемии мозга

Antiutopichesky selective therapy of dyscirculatory encephalopathy in patients with arterial hypotension

The article is devoted to the determination of the effectiveness of the drug Cavinton in women with discirculatory encephalopathy stage I on the background of arterial hypotension. Analysis of the survey results showed a positive effect of treatment with Cavinton obseravations, cerebrovascular, neuropsychological, vegetative disorders in most patients with discirculatory encephalopathy of various blood pressure levels.Статья посвящена определению эффективности препарата кавинтон комфорте у женщин с дисциркуляторной энцефалопатией I стадии на фоне артериальной гипотонии и нормотонии. Анализ результатов исследования показал положительный эффект лечения кавинтоном общегемодинамических, цереброваскулярных, нейропсихологических, вегетативных и тревожных расстройств у большинства больных с дисциркуляторной энцефалопатией на фоне различных цифр артериального давления

Analytical model of brittle destruction based on hypothesis of scale similarity

The size distribution of dust particles in nuclear fusion devices is close to the power function. A function of this kind can be the result of brittle destruction. From the similarity assumption it follows that the size distribution obeys the power law with the exponent between -4 and -1. The model of destruction has much in common with the fractal theory. The power exponent can be expressed in terms of the fractal dimension. Reasonable assumptions on the shape of fragments concretize the power exponent, and vice versa possible destruction laws can be inferred on the basis of measured size distributions.Comment: 10 pages, 3 figure

AUTOIMMUNE ORIGIN OF SARCOIDOSIS: DETERMINATION OF SPECIFIC IMMUNE COMPLEXES IN PATIENTS WITH RESPIRATORY SARCOIDOSIS

The etiology of sarcoidosis is not completely understood. A hypothesis exists about the relationship between sarcoidosis and a complex of pathological autoimmune reactions that occur under the influence of triggering factors. In this study, specific immune complexes in the blood plasma of patients have been determined, which can indirectly reveal the causes of the disease.The study included 33 patients with lung sarcoidosis (I group), compared to 24 healthy donors who served as a control group (II group). The patients underwent standard examination. Their blood plasma was investigated by the dynamic light scattering method with addition of tuberculosis antigens (ESAT-6/SFP-10) and “lung healthy tissue extract”. Statistical analysis was performed using the Statistica 7.0 program. Test results were considered significant at p < 0.05.Аccording to the data obtained, addition of ESAT-6/SFP-10 to patient’s blood plasma almost did not lead to the formation of immune complexes in most samples. Meanwhile, development of such complexes after addition of “lung tissue extract” was revealed in all the patients. The immune complexes were not detected in any donor from control group after stimulation with both kinds of antigens (p < 0.01).The data on distinct formation of immune complexes with the addition of “lung healthy tissue extract” in patients with lung sarcoidosis may be considered an indirect evidence for occurrence of autoimmune reaction under the influence of some pathogenic factors. Absence of de novo immune complex formation after addition of tuberculosis antigens (ESAT-6/SFP-10) makes it unlikely any direct effects of tuberculosis bacteria upon development of sarcoidosis