Perspectives on the future of manufacturing within the Industry 4.0 era

The technological choices facing the manufacturing industry are vast and complex as the industry contemplates the increasing levels of digitization and automation in readiness for the modern competitive age. These changes broadly categorized as Industry 4.0, offer significant transformation challenges and opportunities, impacting a multitude of operational aspects of manufacturing organizations. As manufacturers seek to deliver increased levels of productivity and adaptation by innovating many aspects of their business and operational processes, significant challenges and barriers remain. The roadmap toward Industry 4.0 is complex and multifaceted, as manufacturers seek to transition toward new and emerging technologies, whilst retaining operational effectiveness and a sustainability focus. This study approaches many of these significant themes by presenting a critical evaluation of the core topics impacting the next generation of manufacturers, challenges and key barriers to implementation. These factors are further evaluated via the presentation of a new Industry 4.0 framework and alignment of I4.0 themes with the UN Sustainability Goals

Trends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries

Objective To evaluate outcome trends of neonates born very preterm in 11 high-income countries participating in the International Network for Evaluating Outcomes of neonates. Study design In a retrospective cohort study, we included 154 233 neonates admitted to 529 neonatal units between January 1, 2007, and December 31, 2015, at 24(0/7) to 31(6/7) weeks of gestational age and birth weight <1500 g. Composite outcomes were in-hospital mortality or any of severe neurologic injury, treated retinopathy of prematurity, and bronchopulmonary dysplasia (BPD); and same composite outcome excluding BPD. Secondary outcomes were mortality and individual morbidities. For each country, annual outcome trends and adjusted relative risks comparing epoch 2 (2012-2015) to epoch 1 (2007-2011) were analyzed. Results For composite outcome including BPD, the trend decreased in Canada and Israel but increased in Australia and New Zealand, Japan, Spain, Sweden, and the United Kingdom. For composite outcome excluding BPD, the trend decreased in all countries except Spain, Sweden, Tuscany, and the United Kingdom. The risk of composite outcome was lower in epoch 2 than epoch 1 in Canada (adjusted relative risks 0.78; 95% CI 0.74-0.82) only. The risk of composite outcome excluding BPD was significantly lower in epoch 2 compared with epoch 1 in Australia and New Zealand, Canada, Finland, Japan, and Switzerland. Mortality rates reduced in most countries in epoch 2. BPD rates increased significantly in all countries except Canada, Israel, Finland, and Tuscany. Conclusions In most countries, mortality decreased whereas BPD increased for neonates born very preterm

Influence of shielding gases on preheat produced in surface coatings incorporating SiC particulates into microalloy steel using TIG technique

The use of a tungsten inert gas (TIG) welding torch has resulted in the development of an economical route for surface engineering of alloys, giving similar results to the more expensive high power laser. Due to the preheating generated by both techniques, the extent of the temperature rise is sufficient to produce significant changes to the melt dimensions, microstructure and properties between the first and last tracks melted during the coating of a complete surface. The present study examines if similar changes can occur between the start and finish locations of a single track of 50 mm length. The results show that for a TIG melted surface of a microalloy steel substrate, with or without incorporating preplaced SiC particles, in either argon or argon-helium environments, a maximum temperature of 375°C developed in the second third of the track. Even over this short distance, a hardness decrease of >300 Hv was recorded in the re-solidified SiC coated substrate melt zone, microstructure of a cast iron with cracks were observed. Also porosity was found in all the tracks, with and without preplaced SiC powders

Long wave length oscillations and the GALLEX solar neutrino signal

The recently reported solar neutrino signal in the $^{71}$Ga GALLEX detector adds a new dimension to the solar neutrino puzzle, complementing the previously known signals in $^{37}$Cl and water-Cherenkov detectors. Possible explanations for this new signal in terms of matter-enhanced neutrino oscillations (MSW effect) are already awaiting in the literature. We point out here that long-wavelength vacuum oscillations can furnish an alternative explanation of all three signals simultaneously; such solutions give neutrino spectra with distinctive energy dependence and seasonal time dependence. %This is a Revtex file, which is Latex-based but depends upon inputting the %Revtex style files distributed by APS/Physical Review. For more information, %contact Peggy Sutherland at [email protected], phone (516) 349-7800 ext 674Comment: 11 pages, 3 figures available by conventional mail or fax, MAD/PH/70

Endopolyploidy in Vanda Miss Joaquim (Orchidaceae)

10.1046/j.1469-8137.2003.00797.xNew Phytologist1591279-287NEPH