Ansys multiphysics simulation applying for work blade near steam extraction

В статье ставится задача применения междисциплинарного анализа при расчете околоотборных ступеней паровых турбин. На основе опубликованных работ описываются проблемы, которые необходимо решать при расчете и проектировании лопаточного аппарата. Описывается необходимость разработки унифицированной методики прочностного расчета рабочих лопаток околоотборных ступеней.The purpose of this work is ansys multiphysics simulation applying for work blade near steam extraction. The problems that must be addressed in calculation and design of blading describes on the basis of published works. The development applicability of standardized methods of work blade strength calculation is describe

Expanding the scope of ligand substitution from [M(S2C2Ph2] (M = Ni2+, Pd2+, Pt2+) to afford new heteroleptic dithiolene complexes

The scope of direct substitution of the dithiolene ligand from [M(S2C2Ph2)2] [M = Ni2+ (1), Pd2+ (2), Pt2+ (3)] to produce heteroleptic species [M(S2C2Ph2)2Ln] (n = 1, 2) has been broadened to include isonitriles and dithiooxamides in addition to phosphines and diimines. Collective observations regarding ligands that cleanly produce [M(S2C2Ph2)Ln], do not react at all, or lead to ill-defined decomposition identify soft σ donors as the ligand type capable of dithiolene substitution. Substitution of MeNC from [Ni(S2C2Ph2)(CNMe)2] by L provides access to a variety of heteroleptic dithiolene complexes not accessible from 1. Substitution of a dithiolene ligand from 1 involves net redox disproportionation of the ligands from radical monoanions, –S•SC2Ph2, to enedithiolate and dithione, the latter of which is an enhanced leaving group that is subject to further irreversible reactions

Optical echo in photonic crystals

The dynamics of photonic wavepacket in the effective oscillator potential is studied. The oscillator potential is constructed on a base of one dimensional photonic crystal with a period of unit cell adiabatically varied in space. The structure has a locally equidistant discrete spectrum. This leads to an echo effect, i.e. the periodical reconstruction of the packet shape. The effect can be observed in a nonlinear response of the system. Numerical estimations for porous-silicon based structures are presented for femtosecond Ti:Sapphire laser pump.Comment: 4 page

Inhibitors of the sodium-glucose transporter type 2 and new possibilities for managing vascular age in patients with type 2 diabetes mellitus

The article discusses the pathophysiological mechanisms of the development of vascular aging as a combination of the influence on the  body of  genetic, environmental, regulatory, metabolic and other factors causing biochemical, enzymatic and cellular changes in the arterial vascular bed. The concept of “early vascular aging” and “healthy vascular aging” is defined depending on the ratio of the biological and chronological age of the vessels. The role of diabetes mellitus in increasing vascular stiffness, early vascular aging, as well as the  progression of  atherosclerotic cardiovascular diseases and their complications is considered in detail. Approaches to multifactorial management of vascular age in patients with type 2 diabetes (lifestyle modification with strategy of aggressive treatment of modifiers of atherosclerosis, rejection of bad habits, adherence to dietary recommendations and the use of modern organo- and vasoprotective antidiabetic drugs) are revealed. The mechanism of realization of vasoprotective effects of inhibitors of sodium-glucose transporter-2 (iNGLT-2) is described in detail. The results of completed large random ized trials EMPA-REG Outcome and EMPA-REG BP of the most studied representative of the IGLT-2 group, empagliflozin, are presented. It has been shown that due to their glucose and natriuretic effects, the ability to reduce body weight and blood pressure, improve myocardial metabolism and bioenergetics, decrease the activity of the sympathetic nervous system, as well as positive effects on vascular stiffness, NGLT-2 inhibitors are the drugs of choice in patients with type 2 diabetes mellitus (T2DM) and cardiovascular diseases. This makes it possible to widely use this group of drugs for managing the vascular age of patients and represents a new opportunity in the prevention of vascular aging in T2DM

Modelling fluid dynamics of turbine stages located near steam extraction

The purpose of this work is computational fluid dynamics of turbine stages № 19, 20 located near steam extraction. Design of stages model is described. The main steps of calculations and expected results are presents.Ставится задача проведения газодинамического анализа околоотборного отсека 19-20 ступеней турбины типа Т-100 производства АО «УТЗ». Описывается рассчитываемая модель околоотборного отсека с указанием зон, в которых возможно нарушение равномерного потока. Определяются основные этапы расчеты и ожидаемые результаты

Early Alteration of Nucleocytoplasmic Traffic Induced by Some RNA Viruses

AbstractA HeLa cell line expressing the green fluorescent protein fused to the SV40 T-antigen nuclear localization signal (EGFP-NLS) was established. Fluorescence in these cells was confined to the nuclei. After poliovirus infection, cytoplasmic fluorescence in a proportion of cells could be detected by 1 h postinfection (p.i.) and in virtually all of the fluorescent cells by 2 h p.i. The relocation could be prevented by cycloheximide but not by inhibition of poliovirus replication by guanidine · HCl. Nuclear exit of a protein composed of three copies of GFP fused to the NLS also occurred upon poliovirus infection. A similar redistribution of EGFP-NLS took place upon infection with coxsakievirus B3 and, to a lesser extent, with vesicular stomatitis virus. The EGFP-NLS efflux was not due to the loss of NLS. Thus, some positive-strand and negative-strand RNA viruses trigger a rapid nonspecific relocation of nuclear proteins

Tunka-Rex: the Cost-Effective Radio Extension of the Tunka Air-Shower Observatory

Tunka-Rex is the radio extension of the Tunka cosmic-ray observatory in Siberia close to Lake Baikal. Since October 2012 Tunka-Rex measures the radio signal of air-showers in coincidence with the non-imaging air-Cherenkov array Tunka-133. Furthermore, this year additional antennas will go into operation triggered by the new scintillator array Tunka-Grande measuring the secondary electrons and muons of air showers. Tunka-Rex is a demonstrator for how economic an antenna array can be without losing significant performance: we have decided for simple and robust SALLA antennas, and we share the existing DAQ running in slave mode with the PMT detectors and the scintillators, respectively. This means that Tunka-Rex is triggered externally, and does not need its own infrastructure and DAQ for hybrid measurements. By this, the performance and the added value of the supplementary radio measurements can be studied, in particular, the precision for the reconstructed energy and the shower maximum in the energy range of approximately $10^{17}-10^{18}\,$eV. Here we show first results on the energy reconstruction indicating that radio measurements can compete with air-Cherenkov measurements in precision. Moreover, we discuss future plans for Tunka-Rex.Comment: Proceeding of UHECR 2014, Springdale, Utah, USA, accepted by JPS Conference Proceeding