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Inhibitors of Pyruvate Carboxylase
This review aims to discuss the varied types of inhibitors of biotin-dependent carboxylases, with an emphasis on the inhibitors of pyruvate carboxylase. Some of these inhibitors are physiologically relevant, in that they provide ways of regulating the cellular activities of the enzymes e.g. aspartate and prohibitin inhibition of pyruvate carboxylase. Most of the inhibitors that will be discussed have been used to probe various aspects of the structure and function of these enzymes. They target particular parts of the structure e.g. avidin – biotin, FTP – ATP binding site, oxamate – pyruvate binding site, phosphonoacetate – binding site of the putative carboxyphosphate intermediate
Formation of H by radiative association of H and H in the interstellar medium
We develop the theory of radiative association of an atom and a diatomic
molecule within a close-coupling framework. We apply it to the formation of
H after the low energy collision (below 0.5 eV) of H with H.
Using recently obtained potential energy and permanent dipole moment surfaces
of H, we calculate the lowest rovibrational levels of the H
electronic ground state, and the cross section for the formation of H by
radiative association between H and ortho- and para-H. We discuss the
possibility for the H ion to be formed and observed in the cold and dense
interstellar medium in an environment with a high ionization rate. Such an
observation would be a probe for the presence of H in the interstellar
medium
The Magellanic Bridge: The Nearest Purely Tidal Stellar Population
We report on observations of the stellar populations in twelve fields
spanning the region between the Magellanic Clouds, made with the Mosaic-II
camera on the 4-meter telescope at the Cerro-Tololo Inter-American Observatory.
The two main goals of the observations are to characterize the young stellar
population (which presumably formed in situ in the Bridge and therefore
represents the nearest stellar population formed from tidal debris), and to
search for an older stellar component (which would have been stripped from
either Cloud as stars, by the same tidal forces which formed the gaseous
Bridge). We determine the star-formation history of the young inter-Cloud
population, which provides a constraint on the timing of the gravitational
interaction which formed the Bridge. We do not detect an older stellar
population belonging to the Bridge in any of our fields, implying that the
material that was stripped from the Clouds to form the Magellanic Bridge was
very nearly a pure gas.Comment: 19 pages, 9 figures. Accepted to Ap
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