Quantum phase properties of photon added and subtracted displaced Fock states

Quantum phase properties of photon added and subtracted displaced Fock states (and a set of quantum states which can be obtained as the limiting cases of these states) are investigated from a number of perspectives, and it is shown that the quantum phase properties are dependent on the quantum state engineering operations performed. Specifically, the analytic expressions for quantum phase distributions and angular $Q$ distribution as well as measures of quantum phase fluctuation and phase dispersion are obtained. The uniform phase distribution of the initial Fock states is observed to be transformed by the unitary operation (i.e., displacement operator) into non-Gaussian shape, except for the initial vacuum state. It is observed that the phase distribution is symmetric with respect to the phase of the displacement parameter and becomes progressively narrower as its amplitude increases. The non-unitary (photon addition/subtraction) operations make it even narrower in contrast to the Fock parameter, which leads to broadness. The photon subtraction is observed to be a more powerful quantum state engineering tool in comparison to the photon addition. Further, one of the quantum phase fluctuation parameters is found to reveal the existence of antibunching in both the engineered quantum states under consideration. Finally, the relevance of the engineered quantum states in the quantum phase estimation is also discussed, and photon added displaced Fock state is shown to be preferable for the task.Comment: Quantum phase properties of an engineered quantum state has been studied from various perspective

Lower- and higher-order nonclassical properties of photon added and subtracted displaced Fock states

Nonclassical properties of photon added and subtracted displaced Fock states have been studied using various witnesses of lower- and higher-order nonclassicality. Compact analytic expressions are obtained for the nonclassicality witnesses. Using those expressions, it is established that these states and the states that can be obtained as their limiting cases (except coherent states) are highly nonclassical as they show the existence of lower- and higher-order antibunching and sub-Poissonian photon statistics, in addition to the nonclassical features revealed through the Mandel $Q_M$ parameter, zeros of Q function, Klyshko's criterion, and Agarwal-Tara criterion. Further, some comparison between the nonclassicality of photon added and subtracted displaced Fock states have been performed using witnesses of nonclassicality. This has established that between the two types of non-Gaussianity inducing operations (i.e., photon addition and subtraction) used here, photon addition influences the nonclassical properties more strongly. Further, optical designs for the generation of photon added and subtracted displaced Fock states from squeezed vacuum state have also been proposed.Comment: A comparative study of the nonclassicality present in photon added and subtracted displaced Fock states shows photon addition is generally preferable nonclassicality inducing operation, while subtraction also has advantage in some cases over additio

An ovarian mucinous cystadenoma with adnexal tuberculosis: a case report

We report the occurrence of a case of a benign ovarian tumour- mucinous cystadenoma ovary with adnexal tuberculosis. Our case was a middle-aged Indian woman who presented with abdominal distension and discomfort at the gynaecology clinic of M.Y. hospital, Indore. The data were collected by history-taking, clinical examination, laboratory investigations, transabdominal ultrasonographic examination, and by histopathological study of the excised surgical specimen. It was reported as ovarian mucinous cystadenoma with adnexal TB. This case report emphasizes the significance of thorough evaluation of all women presenting with vague abdominal pains and thorough search of any other pathology in the specimen, like in our case it was tuberculosis. With the increasing awareness of such conditions, more and more cases could be detected and reported.

Impact of photon addition and subtraction on nonclassical and phase properties of a displaced Fock state

Various nonclassical and quantum phase properties of photon added then subtracted displaced Fock state have been examined systematically and rigorously. Higher-order moments of the relevant bosonic operators are computed to test the nonclassicality of the state of interest, which reduces to various quantum states (having applications in quantum optics, metrology and information processing) in different limits ranging from the coherent (classical) state to the Fock (most nonclassical) states. The nonclassical features are discussed using Klyshko's, Vogel's, and Agarwal-Tara's criteria as well as the criteria of lower- and higher-order antibunching, sub-Poissonian photon statistics and squeezing. In addition, phase distribution function and quantum phase fluctuation have been studied. These properties are examined for various combinations of number of photon addition and/or subtraction and Fock parameter. The examination has revealed that photon addition generally improves nonclassicality, and this advantage enhances for the large (small) values of displacement parameter using photon subtraction (Fock parameter). The higher-order sub-Poissonian photon statistics is only observed for the odd orders. In general, higher-order nonclassicality criteria are found to detect nonclassicality even in the cases when corresponding lower-order criteria failed to do so. Photon subtraction is observed to induce squeezing, but only large number of photon addition can be used to probe squeezing for large values of displacement parameter. Further, photon subtraction is found to alter the phase properties more than photon addition, while Fock parameter has an opposite effect of the photon addition/subtraction. Finally, nonclassicality and non-Gaussianity is also established using $Q$ function.Comment: Nonclassical and quantum phase properties of photon added then subtracted displaced Fock state are studied in detai

Cervical Pap smear study and detection of abnormal epithelial lesions and determination of its accuracy by cytohistological correlation in patients of tertiary care teaching hospital in central India

Background: Cervical cancer is the second most common cancer in females and is a major cause of morbidity and mortality. Pap smear is simple, cost effective and sensitive tool for screening of various non-neoplastic and neoplastic lesions of cervix. The objective of this study was to determine the pattern of various cervical smear abnormalities in our center, to study the prevalence of epithelial cell abnormalities in our study population and to determine the accuracy of Pap test by correlating with histopathology.Methods: This was a retrospective study of 7127 cervical pap smears screened and reported at department of pathology, Sri Aurobindo institute of medical sciences Indore, Madhya Pradesh, India during the period of January 2013 to December 2015. Pap smear was done by the conventional method and reporting was done based on the Bethesda system .Emphasis was put on epithelial cell abnormalities and the findings of abnormal epithelial lesions were correlated with histopathology.Results: In this study, the epithelial cell abnormalities constituted 2% of all cases. Low grade squamous intraepithelial lesion was the most common epithelial cell abnormality found in our study group followed by HSIL and then squamous cell carcinoma. About two thirds of the abnormal epithelial lesions were found in the age group above 40 years. Our cytological diagnosis correlated well with histopathology.Conclusions: Pap smear is a cost effective and sensitive screening method for detection of cancerous, pre-cancerous and non-cancerous lesions of cervix

Manipulating nonclassicality via quantum state engineering processes: Vacuum filtration and single photon addition

The effect of two quantum state engineering processes that can be used to burn hole at vacuum in the photon number distribution of quantum states of radiation field are compared using various witnesses of lower- and higher-order nonclassicality as well as a measure of nonclassicality. Specifically, the witnesses of nonclassical properties due to the effect of vacuum state filtration and a single photon addition on an even coherent state, binomial state and Kerr state are investigated using the criteria of lower- and higher-order antibunching, squeezing and sub-Poissonian photon statistics. Further, the amount of nonclassicality present in these engineered quantum states is quantified and analyzed by using an entanglement potential based on linear entropy. It is observed that all the quantum states studied here are highly nonclassical, and on many occasions the hole burning processes are found to introduce/enhance nonclassical features. However, it is not true in general. The investigation has further revealed that despite the fact that a hole at vacuum implies a maximally nonclassical state (as far as Lee's nonclassical depth is used as the quantitative measure of nonclassicality). However, any particular process of hole burning at vacuum does not ensure the existence of a particular nonclassical feature. Specifically,lower- and higher-order squeezing are not observed for photon added even coherent state and vacuum filtered even coherent state.Comment: Effect of holeburning is studied for various engineered quantum state

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease

BACKGROUND: Interstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects in preclinical models of systemic sclerosis and ILD. METHODS: We conducted a randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of nintedanib in patients with ILD associated with systemic sclerosis. Patients who had systemic sclerosis with an onset of the first non-Raynaud's symptom within the past 7 years and a high-resolution computed tomographic scan that showed fibrosis affecting at least 10% of the lungs were randomly assigned, in a 1:1 ratio, to receive 150 mg of nintedanib, administered orally twice daily, or placebo. The primary end point was the annual rate of decline in forced vital capacity (FVC), assessed over a 52-week period. Key secondary end points were absolute changes from baseline in the modified Rodnan skin score and in the total score on the St. George's Respiratory Questionnaire (SGRQ) at week 52. RESULTS: A total of 576 patients received at least one dose of nintedanib or placebo; 51.9% had diffuse cutaneous systemic sclerosis, and 48.4% were receiving mycophenolate at baseline. In the primary end-point analysis, the adjusted annual rate of change in FVC was 1252.4 ml per year in the nintedanib group and 1293.3 ml per year in the placebo group (difference, 41.0 ml per year; 95% confidence interval [CI], 2.9 to 79.0; P=0.04). Sensitivity analyses based on multiple imputation for missing data yielded P values for the primary end point ranging from 0.06 to 0.10. The change from baseline in the modified Rodnan skin score and the total score on the SGRQ at week 52 did not differ significantly between the trial groups, with differences of 120.21 (95% CI, 120.94 to 0.53; P=0.58) and 1.69 (95% CI, 120.73 to 4.12 [not adjusted for multiple comparisons]), respectively. Diarrhea, the most common adverse event, was reported in 75.7% of the patients in the nintedanib group and in 31.6% of those in the placebo group. CONCLUSIONS: Among patients with ILD associated with systemic sclerosis, the annual rate of decline in FVC was lower with nintedanib than with placebo; no clinical benefit of nintedanib was observed for other manifestations of systemic sclerosis. The adverse-event profile of nintedanib observed in this trial was similar to that observed in patients with idiopathic pulmonary fibrosis; gastrointestinal adverse events, including diarrhea, were more common with nintedanib than with placebo

VARTALAAP - A DISTRIBUTED MULTICAST COMMUNICATION-SYSTEM

With the increasing proliferation of computer networks and distributed systems, there is a growing number of applications using multicast communication. This paper presents the Vartalaap system developed at IIT, Bombay. Vartalaap is an hierarchical distributed system for multicast communication over a network, implemented in a hardware-independent fashion. The multicast is achieved without resorting to unnecessary broadcasting of messages over the network. Issues covered in this paper include the primitives for multicast, the multicast model and the system architecture. We discuss the implementation of Vartalaap and compare it with some other systems. We conclude with a discussion on the limitations of the current implementation and directions for future work

Insurance selling and administration The FSA's high-level approach to regulation

Title from coverSIGLEAvailable from British Library Document Supply Centre- DSC:3423. 77522(160) / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Terminal hemimyelocystocele associated with Chiari II malformation

Terminal myelocystocele (TMC) results from failure of embryonic CSF to drain outside the neural tube creating CSF reservoir within a dorsal meningocele. Association of Chiari II malformation with diastematomyelia and myelocystocele is extremely rare. Myelocystoceles do not have neural tissue so they have good prognosis after treatment, however when associated with hydromelia and Chiari malformation they present with neurological deficits. We present details of a 2 year old female who presented to us with this rare anomaly