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Identification of Trace Organic Components in the CR Chondrites by 4D TOFMS
This paper reports preliminary results of a 4D TOFMS study of CR chondrite organic material, highlighting the low-level organic species that may further reveal the complexity of parent body modification of interstellar precursors
Control of scroll wave turbulence using resonant perturbations
Turbulence of scroll waves is a sort of spatio-temporal chaos that exists in
three-dimensional excitable media. Cardiac tissue and the Belousov-Zhabotinsky
reaction are examples of such media. In cardiac tissue, chaotic behaviour is
believed to underlie fibrillation which, without intervention, precedes cardiac
death. In this study we investigate suppression of the turbulence using
stimulation of two different types, "modulation of excitability" and "extra
transmembrane current". With cardiac defibrillation in mind, we used a single
pulse as well as repetitive extra current with both constant and feedback
controlled frequency. We show that turbulence can be terminated using either a
resonant modulation of excitability or a resonant extra current. The turbulence
is terminated with much higher probability using a resonant frequency
perturbation than a non-resonant one. Suppression of the turbulence using a
resonant frequency is up to fifty times faster than using a non-resonant
frequency, in both the modulation of excitability and the extra current modes.
We also demonstrate that resonant perturbation requires strength one order of
magnitude lower than that of a single pulse, which is currently used in
clinical practice to terminate cardiac fibrillation. Our results provide a
robust method of controlling complex chaotic spatio-temporal processes.
Resonant drift of spiral waves has been studied extensively in two dimensions,
however, these results show for the first time that it also works in three
dimensions, despite the complex nature of the scroll wave turbulence.Comment: 13 pages, 12 figures, submitted to Phys Rev E 2008/06/13. Last
version: 2008/09/18, after revie
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Pyrolysis-GCĂ—GC-TOFMS to characterize carbonaceous chondrites
Using pyrolysis-GCxGC-TOFMS to analyze organic carbon in carbonaceous chondrites gives a massive increase in both sensitivity and structural information from samples when compared to traditional Py-GC-MS
Low energy defibrillation in human cardiac tissue: a simulation study.
Copyright © 2009 Biophysical SocietyJournal ArticleWe aim to assess the effectiveness of feedback-controlled resonant drift pacing as a method for low energy defibrillation. Antitachycardia pacing is the only low energy defibrillation approach to have gained clinical significance, but it is still suboptimal. Low energy defibrillation would avoid adverse side effects associated with high voltage shocks and allow the application of implantable cardioverter defibrillator (ICD) therapy, in cases where such therapy is not tolerated today. We present results of computer simulations of a bidomain model of cardiac tissue with human atrial ionic kinetics. Reentry was initiated and low energy shocks were applied with the same period as the reentry, using feedback to maintain resonance. We demonstrate that such stimulation can move the core of reentrant patterns, in the direction that depends on the location of the electrodes and the time delay in the feedback. Termination of reentry is achieved with shock strength one-order-of-magnitude weaker than in conventional single-shock defibrillation. We conclude that resonant drift pacing can terminate reentry at a fraction of the shock strength currently used for defibrillation and can potentially work where antitachycardia pacing fails, due to the feedback mechanisms. Success depends on a number of details that these numerical simulations have uncovered
Frequency response in surface-potential driven electro-hydrodynamics
Using a Fourier approach we offer a general solution to calculations of slip
velocity within the circuit description of the electro-hydrodynamics in a
binary electrolyte confined by a plane surface with a modulated surface
potential. We consider the case with a spatially constant intrinsic surface
capacitance where the net flow rate is in general zero while harmonic rolls as
well as time-averaged vortex-like components may exist depending on the spatial
symmetry and extension of the surface potential. In general the system displays
a resonance behavior at a frequency corresponding to the inverse RC time of the
system. Different surface potentials share the common feature that the
resonance frequency is inversely proportional to the characteristic length
scale of the surface potential. For the asymptotic frequency dependence above
resonance we find a 1/omega^2 power law for surface potentials with either an
even or an odd symmetry. Below resonance we also find a power law omega^alpha
with alpha being positive and dependent of the properties of the surface
potential. Comparing a tanh potential and a sech potential we qualitatively
find the same slip velocity, but for the below-resonance frequency response the
two potentials display different power law asymptotics with alpha=1 and
alpha~2, respectively.Comment: 4 pages including 1 figure. Accepted for PR
Does the effective Lagrangian for low-energy QCD scale?
QCD is not an approximately scale invariant theory. Hence a dilaton field is
not expected to provide a good description of the low-energy dynamics
associated with the gluon condensate. Even if such a field is introduced, it
remains almost unchanged in hadronic matter at normal densities. This is
because the large glueball mass together with the size of the phenomenological
gluon condensate ensure that changes to that condensate are very small at such
densities. Any changes in hadronic masses and decay constants in matter
generated by that condensate will be much smaller that those produced directly
by changes in the quark condensate. Hence masses and decay constants are not
expected to display a universal scaling.Comment: 7 pages (RevTeX), MC/TH 94/0
Little-Parks effect and multiquanta vortices in a hybrid superconductor--ferromagnet system
Within the phenomenological Ginzburg-Landau theory we investigate the phase
diagram of a thin superconducting film with ferromagnetic nanoparticles. We
study the oscillatory dependence of the critical temperature on an external
magnetic field similar to the Little-Parks effect and formation of multiquantum
vortex structures. The structure of a superconducting state is studied both
analytically and numerically.Comment: 7 pages, 1 figure. Submitted to J. Phys.: Condens. Mat
Individual and Multi Vortex Pinning in Systems with Periodic Pinning Arrays
We examine multi and individual vortex pinning in thin superconductors with
periodic pinning arrays. For multi-vortex pinning we observe peaks in the
critical current of equal magnitude at every matching field, while for
individual vortex pinning we observe a sharp drop in the critical current after
the first matching field in agreement with experiments. We examine the scaling
of the critical current at commensurate and incommensurate fields for varied
pinning strength and show that the depinning force at incommensurate fields
decreases faster than at the commensurate fields.Comment: 4 figuure
Progression of myopathology in Kearns-Sayre syndrome
We report on the progression of myopathology by comparing two biopsies from a patient with a Kearns-Sayre-Syndrome. The first biopsy was taken in 1979 and showed 10% ragged-red fibers. Myopathic changes were slight including internal nuclei and fiber splitting in 10% of the fibers. Electron microscopy revealed typical mitochondrial abnormalities with regard to number and shape. In 1989 a second biopsy was performed for an extended analysis of mitochondrial DNA. This time less than 5% of all fibers were ragged-red. Severe myopathic changes could be detected which so far has rarely been reported in mitochondrial cytopathy
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