Trovare lavoro nel nonprofit: il talento al servizio della buona causa

Trovare lavoro nel nonprofit \ue8 un libro utile per conoscere le professioni possibili nel settore nonprofit e orientare professionalmente il lettore, aiutandolo a capire in che modo dovrebbe muoversi per ottenere il lavoro desiderato. Il testo nasce da una ricerca e da una analisi relativa alle numerose professioni del nonprofit e aiuta concretamente nella ricerca e nell\u2019ottenimento del lavoro desiderato

Selenium interaction with human cell functions

We undertook a series of in vitro studies to evaluate the effects of different doses and compounds of selenium on functional activities of human lymphocytes. The NK cell activity and the proliferation and antibody release by cultured lymphocytes were studied. Our studies suggest that an excess of Se may have a detrimental effect on certain immunological parameters. In addition, Se bioavailability more than absolute levels should be considered to better understand the Se role on immune syste

Suspension of photovoltaic panels over water canals ("Canalvoltaico"): technical feasibility, economic and environmental benefits of a Canal-Top solar plant installation in Emilia-omagna, Italy

Solar energy has become an increasingly important part of the global energy mix. In Italy, the photovoltaic power installed has grown by 40% since 2015 and this raises the problem of land use and occupation. A viable alternative, already experienced in India, is placing solar panels on the top of water canals (Canal-Top, in Italian “Canalvoltaico”). It is a relatively new and innovative approach to solar energy installation that offers several advantages, including the potential to generate renewable energy without occupying additional land, reduce water evaporation from canals, and improve water quality by reducing algae growth. The article explores various canal-top solar projects over the world, then a viable application in the Italian region “Emilia- Romagna” is discussed, evaluating specialized designs, installation and maintenance costs, water evaporation reduction and the potential for conflicts with other water uses. Investment opportunities and risks are also discussed. © 2023, AIDI - Italian Association of Industrial Operations Professors. All rights reserved

STRONGLY GLUCOCORTICOID RECEPTOR IMMUNOREACTIVE NEURONS IN THE NEONATAL RAT-BRAIN

BRAIN glucocorticoid receptor (GR) immunoreactivity was studied in the neonatal rat. Already at postnatal days 1-3 strongly GR immunoreactive (IR) neurons were found in the arcuate and paraventricular hypothalamic nuclei. Moderately to strongly GR IR neurons were found in the locus coeruleus and raphe nuclei, while only weakly GR IR neurons were present in the CA1 and CA2 areas of the hippocampus. GR IR increases steadily during the postnatal period reaching adult levels at day 16. Thus, GR may play a role in the maturation of these hypothalamic nuclei and the 5-hydroxytryptamine and noradrenaline neurons, and GR may provide a basis for the ability of stress-induced increases of glucocorticoids to influence distinct brain circuits during postnatal development

Effects of indole-pyruvic acid on sleep and food intake in the rat

Indole-pyruvic acid was studied for its short- and long-term effects on electroencephalographic sleep and on food intake in rats implanted with cortical and muscular electrodes. Following a single injection, indole-pyruvic acid (10-50 mg kg-1 i.p.) reduced by 16-23 min (range) the latency of the first slow-wave episode in a dose-related fashion and produced a significant increase in slow-wave sleep time (12-40%) in doses of 10-30 mg kg-1. Rapid eye movement sleep latency and rapid eye movement sleep time were increased (by 23-37 min) and reduced (57-71%) respectively. The effects of indole-pyruvic acid on slow-wave sleep time were still present after 3, 7 and 14 days of chronic administration (10 mg kg-1 day-1), whereas tolerance to the effect of indole-pyruvic acid on rapid eye movement sleep was observed. Daily food consumption was reduced (20-28%) by acute administration of indole-pyruvic acid (15-30 mg kg-1 i.p.), but tolerance developed after 5 days of repeated injections. These findings are in accordance with previous evidence suggesting that indole-pyruvic acid effects may be related to the activation of central serotonin neurons, which are involved in the inhibitory control of sleep and food intake

Centrally administered neuropeptide Y fails to increase food intake but enhances hypoalgesia in spontaneously hypertensive rats

The effects of intracerebroventricular (i.c.v.) administration of neuropeptide Y (NPY1-36) on food intake and pain sensitivity in hot plate test were studied in spontaneously hypertensive rats (SHRs) and in normotensive Wistar-Kyoto (WKy) rats. In satiated SHRs NPY1-36 failed to significantly increase intake at doses that produced a strong effect in satiated WKy rats (0.25-1.25 nmol). Conversely, both NPY1-36 and the C-terminal fragment NPY13-36, a putative selective agonist for the Y2-receptor for NPY, enhanced the spontaneously occurring hypoalgesia of SHRs, having no effect in WKy rats. The present results indicate that the NPY central systems involved in the control of regulatory functions are differently tuned in SHRs and WKy rats, suggesting possible involvement of these systems in the genesis of hypertension