Quantum mechanics of layers with a finite number of point perturbations

We study spectral and scattering properties of a spinless quantum particle confined to an infinite planar layer with hard walls containing a finite number of point perturbations. A solvable character of the model follows from the explicit form of the Hamiltonian resolvent obtained by means of Krein's formula. We prove the existence of bound states, demonstrate their properties, and find the on-shell scattering operator. Furthermore, we analyze the situation when the system is put into a homogeneous magnetic field perpendicular to the layer; in that case the point interactions generate eigenvalues of a finite multiplicity in the gaps of the free Hamiltonian essential spectrum.Comment: LateX 2e, 48 pages, with 3 ps and 3 eps figure

Navigating institutional pressure in state-socialist and democratic regimes: The case of movement brontosaurus

Using the case of Movement Brontosaurus, a Czech organization founded in state socialist times, this article investigates how civic associations and nongovernmental organizations seeking to promote alternatives to the status quo respond to institutional pressures in different political and social contexts. The case shows that under state socialism, Brontosaurus appeared to conform to state mandates and societal expectations. However, its formal structure was decoupled from many activities to obscure its oppositional intent.After the transition to democracy, the organization was only able to maintain its place in society after it aligned its structure and practices with each other and openly expressed its alternative agenda. The findings demonstrate how social change and alternative lifestyle organizations vary their responses to institutional pressure in ways that enable them to realize their values and pursue their missions while accounting for the political and social contexts in which they are embedded

Incubation of air-pollution-control residues from secondary Pb smelter in deciduous and coniferous organic soil horizons: leachability of lead, cadmium and zinc

Abstract not availableVladislav Chrastný, Aleš Vaněk, Michael Komárek, Juraj Farkaš, Ondřej Drábek, Petra Vokurková, Jana Němcov

Caspase-2 and JNK Activated by Saturated Fatty Acids are Not Involved in Apoptosis Induction but Modulate ER Stress in Human Pancreatic β-cells

Background: Fatty acid-induced apoptosis and ER stress of pancreatic β-cells contribute to the development of type 2 diabetes, however, the molecular mechanisms involved are unclear. Aims: In this study we have tested the role of caspase-2 and suggested ER stress mediator JNK in saturated fatty acid-induced apoptosis of the human pancreatic β-cells NES2Y. Results: We found that stearic acid at apoptosis-inducing concentration activated ER stress signaling pathways, i.e. IRE1α, PERK and ATF6 pathways, in NES2Y cells. During stearic acid-induced apoptosis, JNK inhibition did not decrease the rate of apoptosis nor the activation of caspase-8, -9, -7 and -2 and PARP cleavage. In addition, inhibition of JNK activity did not affect CHOP expression although it did decrease the induction of BiP expression after stearic acid treatment. Caspase-2 silencing had no effect on PARP as well as caspase-8, -9 and -7 cleavage and the induction of CHOP expression, however, it also decreased the induction of BiP expression. Surprisingly, caspase-2 silencing was accompanied by increased phosphorylation of c-Jun. Conclusions: We have demonstrated that caspase-2 as well as JNK are not key players in apoptosis induction by saturated fatty acids in human pancreatic β-cells NES2Y. However, they appear to be involved in the modulation of saturated fatty acid-induced ER stress signaling, probably by a mechanism independent of c-Jun phosphorylation