8,065 research outputs found

    On equivalence of equations solutions of gravity field and homogenous inertia field

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    The metric of a homogenously accelerated system found by Harry Lass is a solution of the Einstein s equation. The metric of an isotropic homogenous field must satisfy the new gravitational equation.Comment: 5 pages, 1 figur

    Introduction to Khovanov Homologies. III. A new and simple tensor-algebra construction of Khovanov-Rozansky invariants

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    We continue to develop the tensor-algebra approach to knot polynomials with the goal to present the story in elementary and comprehensible form. The previously reviewed description of Khovanov cohomologies for the gauge group of rank N-1=1 was based on the cut-and-join calculus of the planar cycles, which are involved rather artificially. We substitute them by alternative and natural set of cycles, not obligatory planar. Then the whole construction is straightforwardly lifted from SL(2) to SL(N) and reproduces Khovanov-Rozansky (KR) polynomials, simultaneously for all values of N. No matrix factorization and related tedious calculations are needed in such approach, which can therefore become not only conceptually, but also practically useful.Comment: 66 page

    Ubiquitous nucleosome unwrapping in the yeast genome

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    Nucleosome core particle is a dynamic structure -- DNA may transiently peel off the histone octamer surface due to thermal fluctuations or the action of chromatin remodeling enzymes. Partial DNA unwrapping enables easier access of DNA-binding factors to their target sites and thus may provide a dominant pathway for effecting rapid and robust access to DNA packaged into chromatin. Indeed, a recent high-resolution map of distances between neighboring nucleosome dyads in \emph{S.cerevisiae} shows that at least 38.7\% of all nucleosomes are partially unwrapped. The extent of unwrapping follows a stereotypical pattern in the vicinity of genes, reminiscent of the canonical pattern of nucleosome occupancy in which nucleosomes are depleted over promoters and well-positioned over coding regions. To explain these observations, we developed a biophysical model which employs a 10-11 base pair periodic nucleosome energy profile. The profile, based on the pattern of histone-DNA contacts in nucleosome crystal structures and the idea of linker length discretization, accounts for both nucleosome unwrapping and higher-order chromatin structure. Our model reproduces the observed genome-wide distribution of inter-dyad distances, and accounts for patterns of nucleosome occupancy and unwrapping around coding regions. At the same time, our approach explains \emph{in vitro} measurements of accessibility of nucleosome-covered binding sites, and of nucleosome-induced cooperativity between DNA-binding factors. We are able to rule out several alternative scenarios of nucleosome unwrapping as inconsistent with the genomic data.Comment: 49 pages; 15 figure

    Entropy production in open quantum systems: exactly solvable qubit models

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    We present analytical results for the time-dependent information entropy in exactly solvable two-state (qubit) models. The first model describes dephasing (decoherence) in a qubit coupled to a bath of harmonic oscillators. The entropy production for this model in the regimes of "complete" and "incomplete" decoherence is discussed. As another example, we consider the damped Jaynes-Cummings model describing a spontaneous decay of a two-level system into the field vacuum. It is shown that, for all strengths of coupling, the open system passes through the mixed state with the maximum information entropy.Comment: 9 pages, 3 figure
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