Strangeness contribution to the vector and axial form factors of the nucleon

The strangeness contribution to the vector and axial form factors of the nucleon is presented for momentum transfers in the range $0.45<Q^2<1.0$ GeV$^2$. The results are obtained via a combined analysis of forward-scattering parity-violating elastic $\vec{e}p$ asymmetry data from the $G^0$ and HAPPEx experiments at Jefferson Lab, and elastic $\nu p$ and $\bar{\nu} p$ scattering data from Experiment 734 at Brookhaven National Laboratory. The parity-violating asymmetries measured in elastic $\vec{e}p$ scattering at forward angles establish a relationship between the strange vector form factors $G_E^s$ and $G_M^s$, with little sensitivity to the strange axial form factor $G_A^s$. On the other hand, elastic neutrino scattering at low $Q^2$ is dominated by the axial form factor, with still some significant sensitivity to the vector form factors as well. The combination of the two data sets allows the simultaneous extraction of $G_E^s$, $G_M^s$, and $G_A^s$ over a significant range of $Q^2$ for the very first time.Comment: 3 pages, 1 figure, will appear in AIP Conference Proceedings for PANIC 200

Cylindrical, periodic surface lattice — theory, dispersion analysis, and experiment

A two-dimensional surface lattice of cylindrical topology obtained via perturbing the inner surface of a cylinder is considered. Periodic perturbations of the surface lead to observation of high-impedance, dielectric-like media and resonant coupling of surface and non-propagating volume fields. This allows synthesis of tailored-for-purpose "coating" material with dispersion suitable, for instance, to mediate a Cherenkov type interaction. An analytical model of the lattice is discussed and coupled-wave equations are derived. Variations of the lattice dispersive properties with variation of parameters are shown, illustrating the tailoring of the structure's electromagnetic properties. Experimental results are presented showing agreement with the theoretical model

Corrections to Gravity due to a Sol Manifold Extra Dimensional Space

The corrections to the gravitational potential due to a Sol extra dimensional compact manifold, denoted as $M_A^3$, are studied. The total spacetime is of the form $M^4\times M_A^3$. The range of the Sol corrections is investigated and compared to the range of the $T^3$ corrections.Comment: 13 pages, 10 figures, published versio

Fe-chitosan complexes for oxidative degradation of emerging contaminants in water: Structure, activity, and reaction mechanism

Versatile and ecofriendly methods to perform oxidations at near-neutral pH are of crucial importance for processes aimed at purifying water. Chitosan, a deacetylated form of chitin, is a promising starting material owing to its biocompatibility and ability to form stable films and complexes with metals. Here, we report a novel chitosan-based organometallic complex that was tested both as homogeneous and heterogeneous catalyst in the degradation of contaminants of emerging concern in water. The stoichiometry of the complex was experimentally verified with different metals, namely, Cu(II), Fe(III), Fe(II), Co(II), Pd(II), and Mn(II), and we identified the chitosan-Fe(III) complex as the most efficient catalyst. This complex effectively degraded phenol, triclosan, and 3-chlorophenol in the presence of hydrogen peroxide. A putative ferryl-mediated reaction mechanism is proposed based on experimental data, density functional theory calculations, and kinetic modeling. Finally, a film of the chitosan-Fe(III) complex was synthesized and proven a promising supported heterogeneous catalyst for water purification

On multiplicities in length spectra of arithmetic hyperbolic three-orbifolds

Asymptotic laws for mean multiplicities of lengths of closed geodesics in arithmetic hyperbolic three-orbifolds are derived. The sharpest results are obtained for non-compact orbifolds associated with the Bianchi groups SL(2,o) and some congruence subgroups. Similar results hold for cocompact arithmetic quaternion groups, if a conjecture on the number of gaps in their length spectra is true. The results related to the groups above give asymptotic lower bounds for the mean multiplicities in length spectra of arbitrary arithmetic hyperbolic three-orbifolds. The investigation of these multiplicities is motivated by their sensitive effect on the eigenvalue spectrum of the Laplace-Beltrami operator on a hyperbolic orbifold, which may be interpreted as the Hamiltonian of a three-dimensional quantum system being strongly chaotic in the classical limit.Comment: 29 pages, uuencoded ps. Revised version, to appear in NONLINEARIT

Strange form factors of the nucleon in a two-component model

The strange form factors of the nucleon are studied in a two-component model consisting of a three-quark intrinsic structure surrounded by a meson cloud. A comparison with the available experimental world data from the SAMPLE, PVA4, HAPPEX and G0 collaborations shows a good overall agreement. The strange magnetic moment is found to be positive, 0.315 nm.Comment: 11 pages, 2 tables, 5 figures, accepted for publication in J. Phys. G. Revised version, new figures, extra table, new results, updated reference

LER-LHC injector workshop summary, and super-Ferric fast cycling injector in the SPS tunnel

A Workshop on a Low Energy Ring (LER) in the LHC tunnel as a main injector was convened at CERN on October 11-12, 2006. We present the outline of the LER based on the presentations, and respond to the raised questions and discussions including the post-workshop studies. We also outline the possibility of using the LER accelerator technologies for the fast cycling injector accelerator in the SPS tunnel (SF-SPS)

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens.

Human CD8+ cytotoxic T lymphocytes (CTLs) are known to play an important role in tumor control. In order to carry out this function, the cell surface-expressed T-cell receptor (TCR) must functionally recognize human leukocyte antigen (HLA)-restricted tumor-derived peptides (pHLA). However, we and others have shown that most TCRs bind sub-optimally to tumor antigens. Uncovering the molecular mechanisms that define this poor recognition could aid in the development of new targeted therapies that circumnavigate these shortcomings. Indeed, present therapies that lack this molecular understanding have not been universally effective. Here, we describe methods that we commonly employ in the laboratory to determine how the nature of the interaction between TCRs and pHLA governs T-cell functionality. These methods include the generation of soluble TCRs and pHLA and the use of these reagents for X-ray crystallography, biophysical analysis, and antigen-specific T-cell staining with pHLA multimers. Using these approaches and guided by structural analysis, it is possible to modify the interaction between TCRs and pHLA and to then test how these modifications impact T-cell antigen recognition. These findings have already helped to clarify the mechanism of T-cell recognition of a number of cancer antigens and could direct the development of altered peptides and modified TCRs for new cancer therapies

(Z)-2-Amino-3-[(E)-benzyl­ideneamino]but-2-enedinitrile

The asymmetric unit of the title compound, C11H8N4, contains two independent mol­ecules. In the crystal structure, inter­molecular N—H⋯N hydrogen bonds link mol­ecules into ribbons extended in the [100] direction

Whole exome sequencing identifies a mutation in thrombomodulin as the genetic cause of a suspected platelet disorder in a family with normal platelet function

Here, we describe a mother and son with a lifelong bleeding tendency and posttraumatic bleeding who were recruited to the UK Genotyping and Phenotyping of Platelets (GAPP) study with a suspected platelet function disorder. However, despite a clinically significant bleeding score, both had normal platelet counts and normal platelet function. The patients’ blood was analyzed by light transmission aggregometry and genotyping by whole exome sequencing, as outlined by the GAPP study. Approximately 25 000 genetic variants were found for each patient as a result of sequencing and were filtered using a specialized bioinformatics pipeline. A heterozygous variant displaying autosomal dominant inheritance (c.1611 C>A) was found in the gene THBD which encodes the glycoprotein thrombomodulin. This sequence change results in a stop codon (p.Cys537Stop) and truncation of the protein and has been previously described in two other families with bleeding events which suggests it may be a recurrent mutation. In summary, this study shows that patients with a suspected platelet disorder but who present with a normal pattern of platelet aggregation should be investigated for defects in nonplatelet genes