Leptogenesis in Theories with Large Extra Dimensions

We study the scenario of baryogenesis through leptogenesis in higher-dimensional theories, in which the scale of quantum gravity is many orders of magnitude smaller than the usual Planck mass. The minimal realization of these theories includes an isosinglet neutrino which feels the presence of large compact dimensions, whereas all the SM particles are localized on a $(1+3)$-dimensional subspace. In the formulation of minimal leptogenesis models, we pay particular attention to the existence of Majorana spinors in higher dimensions. After compactification of the extra dimensions, we obtain a tower of Majorana Kaluza-Klein excitations which act as an infinite series of CP-violating resonators, and derive the necessary conditions for their constructive interference. Based on this CP-violating mechanism, we find that the decays of the heavy Majorana excitations can produce a leptonic asymmetry which is reprocessed into the observed baryonic asymmetry of the Universe by means of out-of-equilibrium sphaleron interactions, provided the reheat temperature is above 5 GeV.Comment: 34 pages, minor rewordings, to appear in Physical Review

Models of Neutrino Masses and Baryogenesis

Majorana masses of the neutrino implies lepton number violation and is intimately related to the lepton asymmetry of the universe, which gets related to the baryon asymmetry of the universe in the presence of the sphalerons during the electroweak phase transition. Assuming that the baryon asymmetry of the universe is generated before the electroweak phase transition, it is possible to dicriminate different classes of models of neutrino masses. While see-saw mechanism and the triplet higgs mechanism are preferred, the Zee-type radiative models and the R-parity breaking models requires additional inputs to generate baryon asymmetry of the universe during the electroweak phase transition.Comment: 27 pages including 5 figures; Review article for Pramana: the Indian Journal of Physic

Detecting small low emission radiating sources

The article addresses the possibility of robust detection of geometrically small, low emission sources on a significantly stronger background. This problem is important for homeland security. A technique of detecting such sources using Compton type cameras is developed, which is shown on numerical examples to have high sensitivity and specificity and also allows to assign confidence probabilities of the detection. 2D case is considered in detail

Species-selective killing of bacteria by antimicrobial peptide-PNAs

This is an open-access article distributed under the terms of the Creative Commons Attribution License, CC BY 4.0 which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Broad-spectrum antimicrobials kill indiscriminately, a property that can lead to negative clinical consequences and an increase in the incidence of resistance. Species-specific antimicrobials that could selectively kill pathogenic bacteria without targeting other species in the microbiome could limit these problems. The pathogen genome presents an excellent target for the development of such antimicrobials. In this study we report the design and evaluation of species-selective peptide nucleic acid (PNA) antibacterials. Selective growth inhibition of B. subtilis, E. coli, K. pnuemoniae and S. enterica serovar Typhimurium in axenic or mixed culture could be achieved with PNAs that exploit species differences in the translation initiation region of essential genes. An S. Typhimurium-specific PNA targeting ftsZ resulted in elongated cells that were not observed in E. coli, providing phenotypic evidence of the selectivity of PNA-based antimicrobials. Analysis of the genomes of E. coli and S. Typhimurium gave a conservative estimate of >150 PNA targets that could potentially discriminate between these two closely related species. This work provides a basis for the development of a new class of antimicrobial with a tuneable spectrum of activity.Peer reviewedFinal Published versio