Minimal SUGRA Model and Collider Signals

The SUSY signals in the dominant stau-neutralino coannihilation region at a 500(800) GeV linear collider are investigated. The region is consistent with the WMAP measurement of the cold dark matter relic density as well as all other current experimental bounds within the mSUGRA framework. The signals are characterized by an existence of very low-energy tau leptons in the final state due to small mass difference between stau_1 and chi_1 (5-15 GeV). We study the accuracy of the mass difference measurement with a 1^deg active mask to reduce a huge SM two-photon background.Comment: 4 pages, 3 figures, Talk presented at ICHEP04, Aug.16-22, Beijing, China, Numerical typos in Table 5 and 6 are corrected, no changes in figures and in other numerical result

The Generalized Counting Rule and Oscillatory Scaling

We have studied the energy dependence of the $pp$ elastic scattering data and the pion-photoproduction data at 90$^\circ$ c.m. angle in light of the new generalized counting rule derived for exclusive processes. We show that by including the helicity flipping amplitudes (with energy dependence given by the generalized counting rule) and their interference with the Landshoff amplitude, we are able to reproduce the energy dependence of all cross-section and spin-correlation (A$_{NN}$) data available above the resonance region. The pion-photoproduction data can also be described by this approach, but in this case data with much finer energy spacing is needed to confirm the oscillations about the scaling behavior.Comment: 5 pages, 4 figs, submitted to PRC rapid com

Signature of strong atom-cavity interaction on critical coupling

We study a critically coupled cavity doped with resonant atoms with metamaterial slabs as mirrors. We show how resonant atom-cavity interaction can lead to a splitting of the critical coupling dip. The results are explained in terms of the frequency and lifetime splitting of the coupled system.Comment: 8 pages, 5 figure

Neutrinos from Stellar Collapse: Comparison of signatures in water and heavy water detectors

Signatures of neutrino and antineutrino signals from stellar collapse in heavy water detectors are contrasted with those in water detectors. The effects of mixing, especially due to the highly dense matter in the supernova core, are studied. The mixing parameters used are those sets allowed by current understanding of available neutrino data: from solar, atmospheric and laboratory neutrino experiments. Signals at a heavy water detector, especially the dominant charged current reactions on deuteron, are very sensitive to some of these sets of allowed mixing parameters. Theoretical uncertainties on supernova neutrino spectra notwithstanding, a combination of supernova measurements with water and heavy water detectors may be able to distinguish many of these mixing possibilities and thus help in ruling out many of them.Comment: 36 pages Latex file, with 13 postscript figures; important improvements in the analysis and more detailed presentation of results. To appear in Phys. Rev.

Determinants Of the Prevalence of Diarrhoea in Adolescents Attending School: A Case Study of an Indian Village School

In developing countries, including India, diarrhoea is a leading killer throughout the age pyramid. However, most of the medical literature on the determinants of diarrhoea focuses only on young children or the elderly, with health policy mainly targeting the former. Thus, the present article attempts to contribute to a better understanding of the determinants of diarrhoea in adolescents -- the understudied population. The paper develops a model using the medical literature, refines it to fit an Indian village context and tests the hypotheses identified through administering a questionnaire to 114 adolescents in an Indian village school. Results confirm the well known importance of household sanitation. In addition, the contribution of the present study is to assert that access to school toilets and usage of school toilets are also crucial. Furthermore, usage of toilets at school varies as a function of gender and the existence of a toilet in the student's household. Finally, the installation of toilets in schools is not enough, sustainable financial models must be found to maintain toilets and induce students to use them

Study of a pair of coupled continuum equations modeling surface growth

In this communication we introduce a pair of coupled continuum equations to model overlayer growth with evaporation-accretion due to thermal or mechanical agitations of the substrate. We gain insight into the dynamics of growth via one-loop perturbative techniques. This allows us to analyze our numerical data. We conclude that there is a crossover behaviour from a roughening regime to a very long-time, large length scale smoothening regime.Comment: 21 pages, 13 figures. Submitted to J. Phys.: Condens. Matte

MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis.

BACKGROUND:Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer that lacks ER/PR and HER2 receptors. Hence, there is urgency in developing new or novel therapeutic strategies for treatment of TNBC. Our study shows that the Monocyte Chemoattractant Protein-1 (MCP-1) is a marker associated with TNBC and may play a key role in TNBC disease progression. EXPERIMENTAL DESIGN:ELISA method was used to measure secreted MCP-1, and mRNA levels were determined by Real-time PCR in numerous cancer cell lines, representing various breast cancer subtypes. Cellular invasiveness was determined by Boyden chamber assay. RESULTS:Our data show that MCP-1 is upregulated in TNBC cell lines both transcriptionally as well as in secreted protein levels compared to ER-positive luminal cell line, MCF-7. Breast cancer patients, with Basal or Claudin-low subtypes, also showed high expression of MCP-1. MCP-1 treatment induced cell invasion in various breast cancer cell types, without affecting cell proliferation. Small molecule antagonists against Chemokine Receptor 2 (CCR2), cognate receptor for MCP-1 as well as the MAP kinase pathway inhibitor U0126 negatively affected MCP-1 induced MCF-7 cell invasion. This suggests that MCP-1-CCR2 axis may regulate invasiveness via the MAP Kinase pathway. Knocking down MCP-1 decreased cell invasion in TNBC cell line BT-549, along with downregulation of key epithelial to mesenchymal transition markers, N-cadherin and Vimentin. CONCLUSION:Our study suggests that MCP-1 mediated pathways could be potential therapeutic targets for the treatment of TNBC, and could reduce cancer health disparities