Eine Phantasie der Allmacht. Vom Versprechen des an die Technologie angepassten Lernens

Die Autoren analysieren nach der Methode der Objektiven Hermeneutik den das brasilianische Werbevideo der Lernplattform "Moodle". Es wird sowohl der Slogan als auch die Bildpräsentation und damit die Funktionsweise der Lernplattform sequenzanalytisch rekonstruiert. Dabei zeigt sich, wie die Lernplattform nicht nur die Funktion der Lehrenden entprofessionalisiert, sondern auch das Vermittelte zur Nebensache gerät. Die Art und Weise, wie die Plattform den Schüler und die Schülerin an sie bindet, wird als reine Anpassung gekennzeichnet. (DIPF/Orig.

Systematic Review of Medicine-Related Problems in Adult Patients with Atrial Fibrillation on Direct Oral Anticoagulants

New oral anticoagulant agents continue to emerge on the market and their safety requires assessment to provide evidence of their suitability for clinical use. There-fore, we searched standard databases to summarize the English language literature on medicine-related problems (MRPs) of direct oral anticoagulants DOACs (dabigtran, rivaroxban, apixban, and edoxban) in the treatment of adults with atri-al fibrillation. Electronic databases including Medline, Embase, International Pharmaceutical Abstract (IPA), Scopus, CINAHL, the Web of Science and Cochrane were searched from 2008 through 2016 for original articles. Studies pub-lished in English reporting MRPs of DOACs in adult patients with AF were in-cluded. Seventeen studies were identified using standardized protocols, and two reviewers serially abstracted data from each article. Most articles were inconclusive on major safety end points including major bleeding. Data on major safety end points were combined with efficacy. Most studies inconsistently reported adverse drug reactions and not adverse events or medication error, and no definitions were consistent across studies. Some harmful drug effects were not assessed in studies and may have been overlooked. Little evidence is provided on MRPs of DOACs in patients with AF and, therefore, further studies are needed to establish the safety of DOACs in real-life clinical practice