Influence of variability of material mechanical properties on seismic performance of steel and steel-concrete composite structures

Modern standards for constructions in seismic zones allow the construction of buildings able to dissipate the energy of the seismic input through an appropriate location of cyclic plastic deformations involving the largest possible number of structural elements, forming thus a global collapse mechanisms without failure and instability phenomena both at local and global level. The key instrument for this purpose is the capacity design approach, which requires an appropriate selection of the design forces and an accurate definition of structural details within the plastic hinges zones, prescribing at the same time the oversizing of non-dissipative elements that shall remain in the elastic field during the earthquake. However, the localization of plastic hinges and the development of the global collapse mechanism is strongly influenced by the mechanical properties of materials, which are characterized by an inherent randomness. This variability can alter the final structural behaviour not matching the expected performance. In the present paper, the influence of the variability of material mechanical properties on the structural behaviour of steel and steel/concrete composite buildings is analyzed, evaluating the efficiency of the capacity design approach as proposed by Eurocode 8 and the possibility of introducing an upper limitation to the nominal yielding strength adopted in the design

Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy

Anthropometric data from three groups of adolescent girls - preoperative adolescent idiopathic scoliosis (AIS), screened for scoliosis and normals were analysed by comparing skeletal data between higher and lower body mass index subsets. Unexpected findings for each of skeletal maturation, asymmetries and overgrowth are not explained by prevailing theories of AIS pathogenesis. A speculative pathogenetic theory for girls is formulated after surveying evidence including: (1) the thoracospinal concept for right thoracic AIS in girls; (2) the new neuroskeletal biology relating the sympathetic nervous system to bone formation/resorption and bone growth; (3) white adipose tissue storing triglycerides and the adiposity hormone leptin which functions as satiety hormone and sentinel of energy balance to the hypothalamus for long-term adiposity; and (4) central leptin resistance in obesity and possibly in healthy females. The new theory states that AIS in girls results from developmental disharmony expressed in spine and trunk between autonomic and somatic nervous systems. The autonomic component of this double neuro-osseous theory for AIS pathogenesis in girls involves selectively increased sensitivity of the hypothalamus to circulating leptin (genetically-determined up-regulation possibly involving inhibitory or sensitizing intracellular molecules, such as SOC3, PTP-1B and SH2B1 respectively), with asymmetry as an adverse response (hormesis); this asymmetry is routed bilaterally via the sympathetic nervous system to the growing axial skeleton where it may initiate the scoliosis deformity (leptin-hypothalamic-sympathetic nervous system concept = LHS concept). In some younger preoperative AIS girls, the hypothalamic up-regulation to circulating leptin also involves the somatotropic (growth hormone/IGF) axis which exaggerates the sympathetically-induced asymmetric skeletal effects and contributes to curve progression, a concept with therapeutic implications. In the somatic nervous system, dysfunction of a postural mechanism involving the CNS body schema fails to control, or may induce, the spinal deformity of AIS in girls (escalator concept). Biomechanical factors affecting ribs and/or vertebrae and spinal cord during growth may localize AIS to the thoracic spine and contribute to sagittal spinal shape alterations. The developmental disharmony in spine and trunk is compounded by any osteopenia, biomechanical spinal growth modulation, disc degeneration and platelet calmodulin dysfunction. Methods for testing the theory are outlined. Implications are discussed for neuroendocrine dysfunctions, osteopontin, sympathoactivation, medical therapy, Rett and Prader-Willi syndromes, infantile idiopathic scoliosis, and human evolution. AIS pathogenesis in girls is predicated on two putative normal mechanisms involved in trunk growth, each acquired in evolution and unique to humans

A stochastic and continuous model of aeolian vibrations of conductors equipped with stockbridge dampers

Suspended conductors and guard wires of overhead electrical transmission lines (OHL) are prone to aeolian vibrations, resulting from the alternate shedding of vortices in the wake of the cable. These vibrations can occur under light to moderate wind and, whenever not properly controlled, can induce wear damage and fatigue failures of the cables. Nonlinear passive control devices such as Stockbridge dampers, hence, are often installed along the line spans to reduce the vibration severity. The technical approach to the assessment of aeolian vibrations is based on the Energy Balance Method (EBM) and relies on the simplifying assumption of mono-modal oscillations. Typical aeolian vibration records, however, clearly show that several modes can be simultaneously excited due to wind variations in time and along the span. Aiming at overcoming the mono-modal vibration assumption of the EBM, in the present paper wind forces are modeled as a narrow band stochastic process, centered around the Strouhal frequency of the conductor and with arbitrary cross-correlation in space. A new approach, based on the well-known smooth endochronic Bouc-Wen model, is developed to describe the hysteretic dynamic response of Stockbridge dampers. An iterative solution strategy based on a stochastically equivalent linear damper model is then developed to investigate aeolian vibrations of a suspended cable with a Stockbridge damper attached along its length

Identification of pigments on a 16th century Persian manuscript by micro-Raman spectroscopy

Micro-Raman spectroscopy was used in combination with other analytical techniques for the in situ study of a Persian Herati lacquered manuscript dated 1530 AD. The text is calligraphied on sized and polished folios, framed in papers tinted in various shades and sparkled with gold leaf, according to a specific gilding technique. The palette of pigments used for the illumination, the coloured frames and the cover was established. Lead white, amorphous carbon, lapis lazuli, red lead and cinnabar were unambiguously identified. The green bottom layer of the lacquer decoration appeared to be composed of mixed orpiment and lapis lazuli. Another green pigment present in the illumination could not be identified although a Raman spectrum was recorded. In order to determine the composition of the different elements of the cover and regions realised with the Marqash technique, complementary analysis was carried out, using x-ray photoelectron and x-ray fluorescence spectroscopy. The results obtained by these analyses can be put in parallel with the Arabic treatises describing the realization of these manuscripts from Persian workshops. Copyright (C) 2004 John Wiley Sons, Ltd

Bayesian forces identification in cable networks with small bending stiffness

The regular monitoring of cable forces is essential for ensuring the safety of cable structures both during construction and throughout their lifetime. This paper aims at developing a vibration-based identification procedure of the axial forces, bending stiffness, and, secondarily, the crossing point position of cable networks. A model constituted by two crossing stays having small bending stiffness and negligible sag effects is considered. The in-plane direct dynamic problem is solved both numerically and through a perturbation approach. The obtained results are compared to the outcomes of a finite element model for verification purposes. The theoretical studies are also supported by experimental tests performed on a real cable-stayed bridge (Haccourt bridge), which provide insights into the dynamics of the system showing that models of cables with small bending stiffness are more appropriate than taut string models. The inverse analysis based on non-linear Bayesian regression is developed and the closed-form asymptotic formulations are used to prove that the bending stiffness, the cable forces, and the crossing point position can be separately identified from a set of observed frequencies. The implemented procedure is then applied to the tested bridge as a proof of concept, showing that the proposed in-plane identification strategy provides satisfactory results

Severe digestive hemorrhages due to ectopic varices affecting the digestive tract

Varices duodénales, rectocoliques, rectale

Detection of Yersinia enterocolitica serogroup O:3 by a PCR method.

Yersinia enterocolitica is the etiologic agent of a range of clinical situations in humans, but only a small number of serotypes are involved. Among these, Y. enterocolitica O:3 is the most frequently implicated. A PCR method was developed to detect Y. enterocolitica O:3. For this purpose, two pairs of primers were designed to amplify two fragments of the rfb cluster of Y. enterocolitica O:3: a 253-bp fragment of the rfbB gene and a 405-bp fragment of the rfbC gene. A specific detection was obtained only with rfbC primers, which yielded a PCR product of the expected size exclusively with pathogenic Y. enterocolitica of serotype O:3. This pair of primers was combined with the ail, inv, and virF primers previously described (H. Nakajima, M. Inoue, T. Mori, K.-I. Itoh, E. Arakawa, and H. Watanabe, J. Clin. Microbiol. 30:2484-2486, 1992) to allow both the detection and the differentiation between Y. pseudotuberculosis, pathogenic Y. enterocolitica of serotype O:3 and other pathogenic Y. enterocolitica

Fourth international colloquium on nonlinear dynamics and control of deep drilling systems, Stavanger, Norway, May 14-16th, 2018

This version of these proceedings are a rectified version of an earlier version of the proceedings. The abstract EFFECTIVENESS ANALYSIS OF ANTI STICK- SLIP TOOLS has been removed from the proceedings as it did not carry the full consent of all partners involved in the research project from which the abstract resulted. Authors agreed that some of the outcomes of the paper require further investigations and clarifications

Evolutionary ecology of facultative paedomorphosis in newts and salamanders

Facultative paedomorphosis is an environmentally induced polymorphism that results in the coexistence of mature, gilled, and fully aquatic paedomorphic adults and transformed, terrestrial, metamorphic adults in the same population. This polymorphism has been of interest to scientists for decades because it occurs in a large number of caudate amphibian taxa as well as in a large diversity of habitats. Numerous experimental and observational studies have been conducted to explain the proximate and ultimate factors affecting these heterochronic variants in natural populations. The production of each alternative phenotype is based on a genotype x environment interaction and research suggests that differences in the environment can produce paedomorphs through several ontogenetic pathways. No single advantage accounts for the maintenance of this polymorphism. Rather, the interplay of different costs and benefits explains the success of the polyphenism across variable environments. Facultative paedomorphosis allows individuals to cope with habitat variation, to take advantage of environmental heterogeneity in the presence of open inches, and to increase their fitness. This process is expected to constitute a first step towards speciation events, and is also an example of biodiversity at the intraspecific level. The facultative paedomorphosis system is thus ripe for future studies encompassing ecology, evolution, behaviour, endocrinology, physiology, and conservation biology. Few other systems have been broad enough to provide varied research opportunities on topics as diverse as phenotypic plasticity, speciation, mating behaviour, and hormonal regulation of morphology. Further research on facultative paedomorphosis will provide needed insight into these and other important questions facing biologists