Mechanisms Used for Genomic Proliferation by Thermophilic Group II Introns

Studies of mobile group II introns from a thermophilic cyanobacterium reveal how these introns proliferate within genomes and might explain the origin of introns and retroelements in higher organisms

Learning to live together: mutualism between self-splicing introns and their hosts

Group I and II introns can be considered as molecular parasites that interrupt protein-coding and structural RNA genes in all domains of life. They function as self-splicing ribozymes and thereby limit the phenotypic costs associated with disruption of a host gene while they act as mobile DNA elements to promote their spread within and between genomes. Once considered purely selfish DNA elements, they now seem, in the light of recent work on the molecular mechanisms regulating bacterial and phage group I and II intron dynamics, to show evidence of co-evolution with their hosts. These previously underappreciated relationships serve the co-evolving entities particularly well in times of environmental stress

Bilancio Sociale 2013. Azienda Ospedaliero Universitaria Ospedali Riuniti

Il Volume tratta dell'accountability in ambito sanitario, con particolare riferimento alle aziende ospedaliere universitarie. Nella trattazione viene data particolare attenzione al valore sociale prodotto e agli effetti di natura etica, sociale e ambientale che le attività svolte hanno sulla collettività