9 research outputs found
Drug Review - Repaglinide: A Short Acting Insulin Secretagogue for Postprandial Hyperglycaemia
No full textType 2 diabetes mellitus is a complex and heterogeneous disorder. The
pathogenesis involves multiple mechanisms which contribute to
hyperglycaemia, most notably impaired insulin secretion by pancreatic
\u3b2-cells, reduced glucose uptake by skeletal muscle and adipose
tissue (peripheral insulin resistance) and increased hepatic glucose
production. Although basal insulin secretion may remain within the
normal range, the meal-time insulin response is blunted or delayed in
patients with type 2 diabetes mellitus, which causes post-prandial
hypoglycaemia.
Drug Review - Repaglinide: A Short Acting Insulin Secretagogue for Postprandial Hyperglycaemia
No full textType 2 diabetes mellitus is a complex and heterogeneous disorder. The
pathogenesis involves multiple mechanisms which contribute to
hyperglycaemia, most notably impaired insulin secretion by pancreatic
β-cells, reduced glucose uptake by skeletal muscle and adipose
tissue (peripheral insulin resistance) and increased hepatic glucose
production. Although basal insulin secretion may remain within the
normal range, the meal-time insulin response is blunted or delayed in
patients with type 2 diabetes mellitus, which causes post-prandial
hypoglycaemia.
Spray dried solid dispersion of repaglinide using hypromellose acetate succinate: in vitro
No full text
Morphological variations of wheat (Triticum aestivum L. em. Thell.) under variable ethyl methanesulphonate mutagenesis
No full text
