11,763 research outputs found

    Phase Coexistence Near a Morphotropic Phase Boundary in Sm-doped BiFeO3 Films

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    We have investigated heteroepitaxial films of Sm-doped BiFeO3 with a Sm-concentration near a morphotropic phase boundary. Our high-resolution synchrotron X-ray diffraction, carried out in a temperature range of 25C to 700C, reveals substantial phase coexistence as one changes temperature to crossover from a low-temperature PbZrO3-like phase to a high-temperature orthorhombic phase. We also examine changes due to strain for films greater or less than the critical thickness for misfit dislocation formation. Particularly, we note that thicker films exhibit a substantial volume collapse associated with the structural transition that is suppressed in strained thin films

    Hartree-Fock-Bogoliubov Calculations in Coordinate Space: Neutron-Rich Sulfur, Zirconium, Cerium, and Samarium Isotopes

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    Using the Hartree-Fock-Bogoliubov (HFB) mean field theory in coordinate space, we investigate ground state properties of the sulfur isotopes from the line of stability up to the two-neutron dripline (34−52S^{34-52}S). In particular, we calculate two-neutron separation energies, quadrupole moments, and rms-radii for protons and neutrons. Evidence for shape coexistence is found in the very neutron-rich sulfur isotopes. We compare our calculations with results from relativistic mean field theory and with available experimental data. We also study the properties of neutron-rich zirconium (102,104Zr^{102,104}Zr), cerium (152Ce^{152}Ce), and samarium (158,160Sm^{158,160}Sm) isotopes which exhibit very large prolate quadrupole deformations.Comment: 7 pages, 6 figures, 2 tables submitted to Phys. Rev.

    Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment

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    Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications. Cardiac involvement is characterized by progressive dilated cardiomyopathy, decreased fractional shortening and metabolic dysfunction involving reduced metabolism of fatty acids—the major cardiac metabolic substrate. Several mouse models have been developed to study molecular and pathological consequences of dystrophin deficiency, but do not recapitulate all aspects of human disease pathology and exhibit a mild cardiac phenotype. Here we demonstrate that Cmah (cytidine monophosphate-sialic acid hydroxylase)-deficient mdx mice (Cmah−/−;mdx) have an accelerated cardiac phenotype compared to the established mdx model. Cmah−/−;mdx mice display earlier functional deterioration, specifically a reduction in right ventricle (RV) ejection fraction and stroke volume (SV) at 12 weeks of age and decreased left ventricle diastolic volume with subsequent reduced SV compared to mdx mice by 24 weeks. They further show earlier elevation of cardiac damage markers for fibrosis (Ctgf), oxidative damage (Nox4) and haemodynamic load (Nppa). Cardiac metabolic substrate requirement was assessed using hyperpolarized magnetic resonance spectroscopy indicating increased in vivo glycolytic flux in Cmah−/−;mdx mice. Early upregulation of mitochondrial genes (Ucp3 and Cpt1) and downregulation of key glycolytic genes (Pdk1, Pdk4, Ppara), also denote disturbed cardiac metabolism and shift towards glucose utilization in Cmah−/−;mdx mice. Moreover, we show long-term treatment with peptide-conjugated exon skipping antisense oligonucleotides (20-week regimen), resulted in 20% cardiac dystrophin protein restoration and significantly improved RV cardiac function. Therefore, Cmah−/−;mdx mice represent an appropriate model for evaluating cardiac benefit of novel DMD therapeutics

    Illuminating dark matter and primordial black holes with interstellar antiprotons

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    Interstellar antiproton fluxes can arise from dark matter annihilating or decaying into quarks or gluons that subsequently fragment into antiprotons. Evaporation of primordial black holes also can produce a significant antiproton cosmic-ray flux. Since the background of secondary antiprotons from spallation has an interstellar energy spectrum that peaks at \sim 2\gev and falls rapidly for energies below this, low-energy measurements of cosmic antiprotons are useful in the search for exotic antiproton sources. However, measurement of the flux near the earth is challenged by significant uncertainties from the effects of the solar wind. We suggest evading this problem and more effectively probing dark-matter signals by placing an antiproton spectrometer aboard an interstellar probe currently under discussion. We address the experimental challenges of a light, low-power-consuming detector, and present an initial design of such an instrument. This experimental effort could significantly increase our ability to detect, and have confidence in, a signal of exotic, nonstandard antiproton sources. Furthermore, solar modulation effects in the heliosphere would be better quantified and understood by comparing results to inverse modulated data derived from existing balloon and space-based detectors near the earth.Comment: 18 pages, 3 figure

    ARPES Study of the Metal-Insulator Transition in Bismuth Cobaltates

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    We present an angle-resolved photoemission spectroscopy (ARPES) study of a Mott-Hubbard-type bismuth cobaltate system across a metal-insulator transition. By varying the amount of Pb substitution, and by doping with Sr or Ba cation, a range of insulating to metallic properties is obtained. We observe a systematic change in the spectral weight of the coherent and incoherent parts, accompanied by an energy shift of the incoherent part. The band dispersion also shows the emergence of a weakly dispersing state at the Fermi energy with increasing conductivity. These changes correspond with the changes in the temperature-dependent resistivity behavior. We address the nature of the coherent-incoherent parts in relation to the peak-dip-hump feature seen in cuprates superconductors

    Positronium oscillations to Mirror World revisited

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    We present a calculation of the branching ratio of orthopositronium decay into an invisible mode, which is done in the context of Mirror World models, where ordinary positronium can disappear from our world due to oscillation into its mirror twin. In this revision we clarify some formulas and approximations used previously, correct them at some places, add new effects relevant for a feasible experiment and finally perform a combined analysis. We include into consideration various effects due to external magnetic and electric fields, collisions with cavity walls and scattering off gas atoms in the cavity. Oscillations of the Rydberg positroniums are also considered. To perform a numerical estimates in a realistic case we wrote computer code, which can be adopted in any experimental setup. Its work is illustrated with an example of a planned positronium experiment within the AEgIS project.Comment: 23 pages, 4 figures, typos corrected, references added, published versio

    Staging superstructures in high-TcT_c Sr/O co-doped La2−x_{2-x}Srx_xCuO4+y_{4+y}

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    We present high energy X-ray diffraction studies on the structural phases of an optimal high-TcT_c superconductor La2−x_{2-x}Srx_xCuO4+y_{4+y} tailored by co-hole-doping. This is specifically done by varying the content of two very different chemical species, Sr and O, respectively, in order to study the influence of each. A superstructure known as staging is observed in all samples, with the staging number nn increasing for higher Sr dopings xx. We find that the staging phases emerge abruptly with temperature, and can be described as a second order phase transition with transition temperatures slightly depending on the Sr doping. The Sr appears to correlate the interstitial oxygen in a way that stabilises the reproducibility of the staging phase both in terms of staging period and volume fraction in a specific sample. The structural details as investigated in this letter appear to have no direct bearing on the electronic phase separation previously observed in the same samples. This provides new evidence that the electronic phase separation is determined by the overall hole concentration rather than specific Sr/O content and concommittant structural details.Comment: 8 pages, incl. 4 figure
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