Oxygen saturation and reported AMS scores at different altitudes.

<p>AMS-c, cerebral score of the environmental symptoms questionnaire score; AMS-LL, acute mountain sickness according to Lake Louise AMS protocol; BC, basecamp, C1–3; camps 1–3; IQR, interquartile range; SpO₂, pulse oximetric arterial oxygen saturation.</p><p>Oxygen saturation and reported AMS scores at different altitudes.</p

Imaging findings pre- and post-expedition in subjects with new microhemorrhages after the climb.

<p>Subject A: Comparison of SWI (MinIP) in pre- and post-expedition MRI shows a new solitary microhemorrhage (indicated by arrow). SWI of Subject B and SWI (MinIP) of subject C show multiple new microhemorrhages of the corpus callosum visible in post-expedition MRI (arrows).</p

Oxygen saturation of all climbers during the expedition.

<p>Oxygen saturation measured by pulse oximetry of all climbers during the expedition. Oxygen saturation measurements of subjects with new findings in post-expedition MRI are indicated in color.</p

Comparison of subjects with and without new MRI findings.

<p>AMS-c, cerebral score of the environmental symptoms questionnaire score; AMS-LL, acute mountain sickness according to Lake Louise AMS protocol; SpO₂, pulse oximetric arterial oxygen saturation.</p><p>Comparison of subjects with and without new MRI findings.</p

Partial volume estimate fractions at baseline and changes between baseline and post-expedition imaging.

<p>Top: Age dependence of the percentages of the partial volume estimates for cerebro-spinal fluid, grey matter and white matter during baseline testing. Means and standard deviations are reported at the bottom of the panels. Bottom: Partial volume estimates fraction change between baseline and post-expedition imagining as a function of age. Means and standard deviations are reported at the bottom of the panels. At the top of the panels the results of a one-sample t-test of the hypothesis that the mean PVE change is zero are given.</p

Summary of total number, total area of retinal hemorrhages (in optic disc areas) and percentage of climbers with hemorrhages per group at different altitudes.

<p>Summary of total number, total area of retinal hemorrhages (in optic disc areas) and percentage of climbers with hemorrhages per group at different altitudes.</p

Fundus photographs of a climber from group 1 showing the development of retinal hemorrhages during the course of her climb.

<p>Note the white-centered hemorrhage localized at the temporal inferior branch of the retinal artery.</p

Graphs describing hemorrhages in both groups of climbers at different altitudes.

<p>Panel A: total number of hemorrhages; panel B: total area of hemorrhages; panel C: percentage of mountaineers with hemorrhages in at least 1 eye.</p

Results of multiple regression analysis performed with total number and total area of hemorrhages and various independent predictors.

<p>Results of multiple regression analysis performed with total number and total area of hemorrhages and various independent predictors.</p