12 research outputs found
EMMPRIN and ADAM12 in prostate cancer: preliminary results of a prospective study
No full textExtracellular metalloproteinase inducer (EMMPRIN) and a disintegrin and metalloproteinase (ADAM12) play a major role in cancer invasion and metastasis owing to the fact that they are directly related to the cell microenvironment and extracellular matrix (ECM) degradation. The aim of this study was to search for an answer to the question "whether the determination of EMMPRIN and ADAM12 values especially in urine may be helpful for the early diagnosis of prostate cancer without employing invasive methods" and also to check whether they may be useful for the determination of the patients with high metastasis risk. Peripheral blood and urine from 66 prostate cancer patients (40 local, 20 locally advanced, 6 metastatic) and 14 healthy controls were evaluated by enzyme-linked immunosorbent assay (ELISA) method. Serum EMMPRIN and ADAM12 values of the patients were seen to be statistically higher than the serum EMMPRIN and ADAM12 values of the healthy controls (p = 0.01 and p = 0.001, respectively). The urine ADAM12 levels were significantly higher in patients (p = 0.013). No significant relationships were found between urine EMMPRIN values of the patients and the healthy controls (p > 0.05). Positive correlation between urine EMMPRIN-urine ADAM12 tests was found in total patients group (r = 0.683, p = 0.001). Our preliminary results revealed that serum EMMPRIN and ADAM12 values and urine ADAM12 values may be useful markers in prostate cancer therapy. Due to the high correlation between these two tests, we are of the opinion that the use of urine ADAM12 in clinic may be sufficient and favorable together with prostate-specific antigen (PSA) for treatment
SELF-RETAINING BARBED SUTURE FOR RENORRHAPHY REDUCES WARM ISCHEMIA TIME SIGNIFICANTLY DURING LAPAROSCOPIC PARTIAL NEPHRECTOMY: OUTCOMES OF A MATCH-PAIR ANALYSIS
No full textA SINGLE CENTER EXPERIENCE ON LAPAROSCOPIC PARTIAL NEPHRECTOMY: EARLY AND INTERMEDIATE TERM ONCOLOGICAL OUTCOMES
No full textTHE EFFECT OF 'OFF-CAMPING TECHNIQUE' ON EARLY POSTOPERATIVE RENAL RESERVE IN LAPAROSCOPIC PARTIAL NEPHRECTOMY: THE OUTCOMES OF A MATCHED-PAIR ANALYSIS
No full textWARM ISCHEMIA TIME LONGER THAN 30 MINUTES IN LAPAROSCOPIC PARTIAL NEPHRECTOMY SIGNIFICANTLY REDUCES POSTOPERATIVE GLOMERULAR FILTRATION RATES THAT MAY NOT BE REFLECTED TO EARLY AND MID-TERM FOLLOW-UPS
No full textLaparoskopik parsiyel nefrektomide sıcak iskemi süresinin glomerüler filtrasyon hızına gerçekten etkisi var mıdır?: Tek bir merkez erken-orta dönem sonuçlar
No full textWarm ıschemıa tıme longer than 30 mınutes ın laparoscopıc partıal nephrectomy sıgnıfıcantly reduces postoperatıve glomerular fıltratıon rates that may not be reflected to early and mıd-term follow-ups
No full text
THE COMPARISON OF ONCOLOGICAL OUTCOMES OL LAPAROSCOPIC PARTIAL AND RADICAL NEPHRECFTOMIES FOR RENAL TUMORS SIZED BETWEEN 4-7 CM: A SINGLE CENTER EXPERIENCE
No full textThe use of self-retaining barbed suture for inner layer renorrhaphy significantly reduces warm ischemia time in laparoscopic partial nephrectomy: outcomes of a matched-pair analysis.
No full textPurpose: To investigate the efficacy of self-retaining barbed suture (SRBS) on reducing renorrhaphy time and warm ischemia time (WIT) during laparoscopic partial nephrectomy (LPN), in comparison with conventional polyglactin suture
