Open reduction technique for overlapping and locked pubic symphysis

A locked pubic symphysis can occur following a lateral compression injury of the pelvic ring when one pubic bone becomes entrapped behind the contralateral pubis or obturator foramen, In selecting the treatment modality, it is important to know the mechanism of injury. We presented the use of an open reduction technique in the treatment of a locked pubic symphysis in which open reduction external fixation application failed in the emergency department

Endoscopic calcaneoplasty: five-year results

Objective: The aim of this study was to evaluate the results of the endoscopic calcaneoplasty technique for the treatment of retrocalcaneal bursitis and Haglund's disease

Anatomic relationship between elbow arthroscopy portals and neurovascular structures in different elbow and forearm positions

Twenty fresh codaveric elbows were used to evaluate the proximity of neurovascular structures to the six arthroscopic portals of the elbow at different positions. After distention of the joint, 4-mm Steinmann pins were introduced into the elbow from the portal's entry points. After surgical dissection, the proximity of the neurovascular structures to the pins was measured in 5 different positions. The radial nerve showed significant proximity to the anterolateral portal in full elbow flexion, full elbow extension, and forearm supination with 10%, 20%, and 10% nerve-pin contacts, respectively. The distance between the median nerve and medial portals was significantly decreased with full extension. This study demonstrated that the distance between the route of the scope and neurovascular structures might diminish significantly during elbow motion. Most of these movements are unavoidable in elbow arthroscopy, but maintaining certain positions for a considerable period of time or angulating the scope forcefully in these positions can cause nerve injury

A case of brown tumor mimicking fibrous dysplasia in a patient with chronic renal failure

Renal osteodystrophy is one of the major causes of morbidity in patients receiving long-term dialysis treatment for renal failure and after transplantation. Its clinical implications include high-turnover bone disease, low-turnover bone disease, osteomalacia. osteosclerosis, and osteoporosis. A 13-year-old boy who had been on dialysis treatment for renal failure was admitted with a pathologic supracondylar femur fracture after a minor trauma. Radiological studies showed cystic lesions in the femoral supracondyle, left acetabular roof, and right proximal and distal tibia. Based on radiologic appearances of the lesions and on histopathologic findings of the lesion excised from the right distal tibia, brown tumor and fibrous dysplasia were considered in the differential diagnosis. Initially, serum parathyroid hormone level was slightly increased and calcium level was normal. but during follow-up, serum parathyroid hormone level increased significantly, enabling the diagnosis of brown tumor

Intramedullary nail with integrated cephalocervical screws in the intertrochanteric fractures treatment: Position of screws in fracture stability

BACKGROUND:Stable fracture fixation is important in the treatment of intertrochanteric femur (ITF) fractures in the elderly population to prevent the loss of reduction, achieve early mobility, and restore independence. The aim of this study was to present the results of surgical treatment of stable and unstable ITF fractures using a trochanteric antegrade intramedullary nail with two cephalocervical screws in an integrated mechanism (Intertan (R); Smith & Nephew, Memphis, TN) and evaluate the relationship between the loss of reduction and screw position in the femoral neck in two planes

Abnormal Proximal Musculotendinous Junction of the Peroneus Brevis Muscle as a Cause of Peroneus Brevis Tendon Tears: A Cadaveric Study

Abnormal musculotendinous distal extension of the peroneus brevis has been implicated as a possible cause of peroneus brevis tendon tears. We investigated this relationship in 58 (46 male) fresh human cadavers. Torn lesions were classified according to Sobel et al. Musculotendinous distal extension of the peroneus brevis was measured in each ankle as the vertical distance from the musculotendinous junction of the peroneus brevis to the tip of the fibula. Tendons with and without tears were compared by sex, age at death, height, musculotendinous distal extension of the peroneus brevis, the common sheath bifurcation-fibular tip distance, the peroneus brevis and longus width at the musculotendinous junction, fibular groove depth, peroneal tubercle height, superior-inferior peroneal retinaculum wideness, and the presence of the peroneus quartus or an accessory peroneal muscle. Of 115 evaluable tendons, 15 (13%) had tears. All came from men. The average distance from the musculotendinous junction to the tip of the fibula was 27.0 mm in tendons with tears and 16.4 mm in tendons without (P=.04) Male sex (P=.03), age at death (P=.03), height (P=.04), and fibular groove depth (P=.003) were also related to the presence of tears. Our results do not support a relationship between abnormal musculotendinous distal extension of the peroneus brevis and peroneus brevis tendon tears; rather, proximal extension of the peroneus brevis musculotendinous junction may be related to peroneus brevis tendon tears. (C) 2010 by the American College of Foot and Ankle Surgeons. All rights reserved

Understanding lipid metabolism in high-lipid-producing Chlorella vulgaris mutants at the genome-wide level

In this study, physical and chemical mutagenesis methods were applied to enhance lipid productivity in Chlorella vulgaris. Then, de novo RNA-seq was performed to observe lipid metabolism changes at the genome-wide level. Characterization of two mutants, UV-715 and EMS-25, showed marked increases in lipid contents, i.e., 42% and 45%, respectively. In addition, the biomass productivity of the UV-715 cells was 9% higher than that of wildtype cells. Furthermore, gas chromatography-mass spectrophotometry analysis showed that both mutants have higher fatty acid methyl ester (FAME) contents than wild-type cells. To understand the effect of mutations that caused yield changes in UV-715 and EMS-25 cells at a genome-wide level, we carried out de novo RNA-seq. As expected, the transcriptional levels of the lipid biosynthesis genes were up-regulated, while the transcriptional levels of genes involved in lipid catabolism were down-regulated. Surprisingly, the transcriptional levels of the genes involved in nitrate assimilation and detoxification of reactive oxygen species (ROS) were significantly increased in the mutants. The genome-wide analysis results highlight the importance of nitrate metabolism and detoxification of ROS for high biomass and lipid productivity