Cardiopoietic cell therapy for advanced ischemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial

Cardiopoietic cells, produced through cardiogenic conditioning of patients' mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial aimed to validate cardiopoiesis-based biotherapy in a larger heart failure cohort

Model for the Supply Chain Management Based on the Interval Type-2 Fuzzy Numbers and the TOPSIS method

The Performance improvement that leads to an increase in business efficiency, both for the enterprises integrated in the supply chain and the entire supply chain, represents one of the basic strategic management problems. A solution to this problem, among other things, can be obtained by measuring and improving the performance of the supply chain, which simultaneously represents the basic purpose of this research study. The relative importance of performances and the values of their key performance indices are assessed by decision-makers. Their assessments are described by linguistic variables, which are modelled by interval fuzzy numbers type-2. The relative importance of performance is obtained by defining the fuzzy matrix of the relative importance of each pair of performances. The weight values of performances are calculated by means of the eigenvector method. Performance values are calculated by using the fuzzy middle-value operator. The rank of the enterprises, with respect to all of the considered performances as well as their weights, is determined by applying conventional TOPSIS. The ranking of the enterprises integrated in the supply chain can be marked as the main result of the research. On the basis of the obtained rank, appropriate measures can be taken to improve the performance of those enterprises that are rated the worst by respecting all the observed performances. The proposed model has been tested on the real life data from the automotive supply chain operating in Central Serbia

CCDC 729244: Experimental Crystal Structure Determination

Related Article: V.D.Miletic, A.Meetsma, P.J.van Koningsbruggen, Z.D.Matovic|2009|Inorg.Chem.Commun.|12|720|doi:10.1016/j.inoche.2009.05.029,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Additional file 4 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

Additional file 4: Supplemental results.1. README. 2. Prevalence range across districts. 3. Prevalence range between sexes. 4. Prevalence range between ages. 5. Age-specific district ranges