1,587 research outputs found

    Infinite loop spaces and nilpotent K-theory

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    Using a construction derived from the descending central series of the free groups, we produce filtrations by infinite loop spaces of the classical infinite loop spaces BSUBSU, BUBU, BSOBSO, BOBO, BSpBSp, BGL(R)+BGL_{\infty}(R)^{+} and Q0(S0)Q_0(\mathbb{S}^{0}). We show that these infinite loop spaces are the zero spaces of non-unital EE_\infty-ring spectra. We introduce the notion of qq-nilpotent K-theory of a CW-complex XX for any q2q\ge 2, which extends the notion of commutative K-theory defined by Adem-G\'omez, and show that it is represented by Z×B(q,U)\mathbb Z\times B(q,U), were B(q,U)B(q,U) is the qq-th term of the aforementioned filtration of BUBU. For the proof we introduce an alternative way of associating an infinite loop space to a commutative I\mathbb{I}-monoid and give criteria when it can be identified with the plus construction on the associated limit space. Furthermore, we introduce the notion of a commutative I\mathbb{I}-rig and show that they give rise to non-unital EE_\infty-ring spectra.Comment: To appear in Algebraic and geometric topolog

    SUPERMAN, a regulator of floral homeotic genes in Arabidopsis

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    We describe a locus, SUPERMAN, mutations in which result in extra stamens developing at the expense of the central carpels in the Arabidopsis thaliana flower. The development of superman flowers, from initial primordium to mature flower, is described by scanning electron microscopy. The development of doubly and triply mutant strains, constructed with superman alleles and previously identified homeotic mutations that cause alterations in floral organ identity, is also described. Essentially additive phenotypes are observed in superman agamous and superman apetala2 double mutants. The epistatic relationships observed between either apetala3 or pistillata and superman alleles suggest that the SUPERMAN gene product could be a regulator of these floral homeotic genes. To test this, the expression patterns of AGAMOUS and APETALA3 were examined in superman flowers. In wild-type flowers, APETALA3 expression is restricted to the second and third whorls where it is required for the specification of petals and stamens. In contrast, in superman flowers, APETALA3 expression expands to include most of the cells that would normally constitute the fourth whorl. This ectopic APETALA3 expression is proposed to be one of the causes of the development of the extra stamens in superman flowers. The spatial pattern of AGAMOUS expression remains unaltered in superman flowers as compared to wild-type flowers. Taken together these data indicate that one of the functions of the wild-type SUPERMAN gene product is to negatively regulate APETALA3 in the fourth whorl of the flower. In addition, superman mutants exhibit a loss of determinacy of the floral meristem, an effect that appears to be mediated by the APETALA3 and PISTILLATA gene products

    Exploring the impact of innovation in promoting sustainable tourism development: The role of key stakeholders on the top of the south aquaculture and seafood trail in Nelson/Marlborough, New Zealand

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    Contemporary tourism planning recognises that an integrated and sustainable development approach includes the participation of local communities and residents. Community level innovation and leadership is also important in creating and implementing new ideas as part of the development process. The purpose of this study was to evaluate stakeholder perspectives regarding community capacity to link tourism and aquaculture opportunities in the Nelson/Marlborough Region on the South Island of New Zealand. In 2005 the Marine Farming Association developed and published the “Top of the South Aquaculture and Seafood Trail” as a brochure for tourists to promote a positive image of aquaculture in the region. The Trail integrates local tourism providers, restaurants, accommodations, seafood retail, as well as harvesting and processing businesses (mussel farms) as part of a themed driving route. There is a strong economic dependence on aquaculture and tourism in the region with both industries generating a combined $402 million annually in the Nelson Region alone. In conducting the research, 22 local stakeholders were interviewed regarding their perceptions about strengths, weaknesses, threats and opportunities associated with the Trail as part of a mixed method, case study approach. The results demonstrated that tourism in the region was well developed, that there were weaknesses in networking and collaboration, that there were gaps between perceptions of the aquaculture and tourism industries and that the role of the university has been important in building community capacity for research and strategic planning linked to the trail

    Movement speed is biased by prior experience

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    © 2013 The American Physiological Society. This is an Open Access article licensed under the Creative Commons Attribution license CC BY 3.0 https://creativecommons.org/licenses/by/3.0/deed.en_US which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.How does the motor system choose the speed for any given movement? Many current models assume a process that finds the optimal balance between the costs of moving fast and the rewards of achieving the goal. Here, we show that such models also need to take into account a prior representation of preferred movement speed, which can be changed by prolonged practice. In a time-constrained reaching task, human participants made 25-cm reaching movements within 300, 500, 700, or 900 ms. They were then trained for 3 days to execute the movement at either the slowest (900-ms) or fastest (300-ms) speed. When retested on the 4th day, movements executed under all four time constraints were biased toward the speed of the trained movement. In addition, trial-to-trial variation in speed of the trained movement was significantly reduced. These findings are indicative of a use-dependent mechanism that biases the selection of speed. Reduced speed variability was also associated with reduced errors in movement amplitude for the fast training group, which generalized nearly fully to a new movement direction. In contrast, changes in perpendicular error were specific to the trained direction. In sum, our results suggest the existence of a relatively stable but modifiable prior of preferred movement speed that influences the choice of movement speed under a range of task constraints.Peer reviewedFinal Published versio

    Dealing with Data Challenges when Delivering Data-Intensive Software Solutions

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    The predicted increase in demand for data-intensive solution development is driving the need for software, data, and domain experts to effectively collaborate in multi-disciplinary data-intensive software teams (MDSTs). We conducted a socio-technical grounded theory study through interviews with 24 practitioners in MDSTs to better understand the challenges these teams face when delivering data-intensive software solutions. The interviews provided perspectives across different types of roles including domain, data and software experts, and covered different organisational levels from team members, team managers to executive leaders. We found that the key concern for these teams is dealing with data-related challenges. In this paper, we present the theory of dealing with data challenges that explains the challenges faced by MDSTs including gaining access to data, aligning data, understanding data, and resolving data quality issues; the context in and condition under which these challenges occur, the causes that lead to the challenges, and the related consequences such as having to conduct remediation activities, inability to achieve expected outcomes and lack of trust in the delivered solutions. We also identified contingencies or strategies applied to address the challenges including high-level strategic approaches such as implementing data governance, implementing new tools and techniques such as data quality visualisation and monitoring tools, as well as building stronger teams by focusing on people dynamics, communication skill development and cross-skilling. Our findings have direct implications for practitioners and researchers to better understand the landscape of data challenges and how to deal with them.Comment: Submitted to IEEE Transactions on Software Engineering, 22 pages, 4 Figures, 1 Tabl

    Assessment of the kidneys: magnetic resonance angiography, perfusion and diffusion

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    Renal magnetic resonance (MR) imaging has undergone major improvements in the past several years. This review focuses on the technical basics and clinical applications of MR angiography (MRA) with the goal of enabling readers to acquire high-resolution, high quality renal artery MRA. The current role of contrast agents and their safe use in patients with renal impairment is discussed. In addition, an overview of promising techniques on the horizon for renal MR is provided. The clinical value and specific applications of renal MR are critically discussed
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