Additional file 2 of Involving supermarkets in health promotion interventions in the Danish Project SoL. A practice-oriented qualitative study on the engagement of supermarket staff and managers

Supplementary Material

Additional file 1 of Involving supermarkets in health promotion interventions in the Danish Project SoL. A practice-oriented qualitative study on the engagement of supermarket staff and managers

Supplementary Material

Additional file 3 of Involving supermarkets in health promotion interventions in the Danish Project SoL. A practice-oriented qualitative study on the engagement of supermarket staff and managers

Supplementary Material

Letter to the editor: neurofibromatosis type 1 (NF 1) associated with embryonal rhabdomyosarcoma of the orbit.

Information on the 50 SNPs included in this study. The individual SNPs are grouped according to their associated trait. (DOCX 19 kb

Additional file 7: of Alcohol consumption and its interaction with adiposity-associated genetic variants in relation to subsequent changes in waist circumference and body weight

Annual change in BW, WC and WCBMI per 1 alcohol unit/day increase in alcohol intake. (DOCX 14 kb

Additional file 2: of Alcohol consumption and its interaction with adiposity-associated genetic variants in relation to subsequent changes in waist circumference and body weight

Interaction between each risk allele and alcohol intake (1 unit increase) in relation to ΔBW (kg/year). Model adjusted for baseline measure of the anthropometrical variables of interest, age, gender, height, smoking status, education, PA, menopausal status and total energy intake. (DOCX 33 kb

Ο Γέρων αρματωλός της Ίδης, ήτοι, Τρεις πρωτότυποι αυτού επιστολαί περί της ηρωϊκής της Κρήτης επαναστάσεως.

Information on the 50 SNPs included in this study. The individual SNPs are grouped according to their associated trait. (DOCX 19 kb

Change of body weight or waist circumference pr. 5 energy % protein replacing carbohydrate or fat.

<p>Change of body weight or waist circumference pr. 5 energy % protein replacing carbohydrate or fat.</p

Interaction of SNP-scores and protein intake.

<p>Average, yearly waist change (mm/y/5 E% protein/risk allele). A: protein replacing carbohydrate. B: protein replacing fat. SNP-score×protein interactions were calculated using linear regression and pooled estimates were calculated using random effect meta-analysis. The effect-estimates from the individual cohorts were weighted by the inverses of their variance (% weight). The results were adjusted for baseline waist circumference, height, sex, smoking status, physical activity, education, menopausal status for women and concurrent change in body weight. Abbreviations: BMI-score, sum of body mass index associated risk-alleles; WC-score, sum of waist circumference associated risk-alleles; WHR_BMI-score, sum of waist-hip ratio adjusted for BMI associated risk-alleles.</p

Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity

<div><p>Studies of the relationship between serum 25-hydroxyvitamin D (25(OH)D) and changes in measures of adiposity have shown inconsistent results, and interaction with genetic predisposition to obesity has rarely been examined. We examined whether 25(OH)D was associated with subsequent annual changes in body weight (ΔBW) or waist circumference (ΔWC), and whether the associations were modified by genetic predisposition to a high BMI, WC or waist-hip ratio adjusted for BMI (WHR_BMI). The study was based on 10,898 individuals from the Danish <i>Inter99</i>, the <i>1958 British Birth Cohort</i> and the <i>Northern Finland Birth Cohort 1966</i>. We combined 42 adiposity-associated Single Nucleotide Polymorphisms (SNPs) into four scores indicating genetic predisposition to BMI, WC and WHR_BMI, or all three traits combined. Linear regression was used to examine the association between serum 25(OH)D and ΔBW or ΔWC, SNP-score × 25(OH)D interactions were examined, and results from the individual cohorts were meta-analyzed. In the meta-analyses, we found no evidence of an association between 25(OH)D and ΔBW (-9.4 gram/y per 10 nmol/L higher 25(OH)D [95% CI: -23.0, +4.3; P = 0.18]) or ΔWC (-0.06 mm/y per 10 nmol/L higher 25(OH)D [95% CI: -0.17, +0.06; P = 0.33]). Furthermore, we found no statistically significant interactions between the four SNP-scores and 25(OH)D in relation to ΔBW or ΔWC. Thus, in view of the narrow CIs, our results suggest that an association between 25(OH)D and changes in measures of adiposity is absent or marginal. Similarly, the study provided evidence that there is either no or very limited dependence on genetic predisposition to adiposity.</p></div