Project MOMs: Mothers, mOvement, and Maternal Health Care Providers Study

Objective. To examine maternal health care providers (MHCP) physical activity (PA) habits compared to PA prescription habits. To determine barriers, perspectives, and knowledge about PA prescription. Methods. The study contained 104 participants spread across a variety of locations, OBGYN professions, and racial backgrounds. Participants consisted of 87% females, 71% married, 53% with children, and 90% current full-time employees. Each participant was recruited to complete a survey consisting of questions from The International Physical Activity Questionnaire15, Barriers to Prescribing Physical Activity Questionnaire16, and Demographics Questionnaire. Results. The relationship between PA habits and PA prescription practices was calculated using Pearson Correlation Chi-Square analysis. A statistically significant relationship was found between vigorous activity and PA prescription. In addition, 45% of participants listed lack of time as “very much� a barrier. Most MHCP consider their knowledge of PA prescription poor or average, do not have formal training, and do not inquire about PA at every visit. Discussion. The purpose of analyzing the relationship between MHCP PA levels and PA prescription habits was to determine if provider personal PA habits has an impact on their PA prescription habits. The results concluded that there is a statistically significant relationship between MHCP vigorous activity and PA prescription levels. This supports the hypothesis that MHCP who are more often vigorously physically active also prescribe PA a higher percent of the time. Additionally, most providers face barriers to PA prescription including lack of time and perceived patient disinterest

Quay voices in Glasgow museums : an oral history of Glasgow dock workers

Notes on oral history project commissioned by Glasgow museums about Glasgow dock workers

Effects of the Selective Serotonin Reuptake Inhibitor Fluoxetine on Developing Neural Circuits in a Model of the Human Fetal Cortex

The developing prenatal brain is particularly susceptible to environmental disturbances. During prenatal brain development, synapses form between neurons, resulting in neural circuits that support complex cognitive functions. In utero exposure to environmental factors such as pharmaceuticals that alter the process of synapse formation increases the risk of neurodevelopmental abnormalities. However, there is a lack of research into how specific environmental factors directly impact the developing neural circuitry of the human brain. For example, selective serotonin reuptake inhibitors are commonly used throughout pregnancy to treat depression, yet their impact on the developing fetal brain remains unclear. Recently, human brain models have provided unprecedented access to the critical window of prenatal brain development. In the present study, we used human neurons and cortical spheroids to determine whether the selective serotonin reuptake inhibitor fluoxetine alters neurite and synapse formation and the development of spontaneous activity within neural circuits. We demonstrate that cortical spheroids express serotonin transporter, thus recapitulating the early developmental expression of serotonin transporter associated with cortical pyramidal neurons. Cortical spheroids also appropriately express serotonin receptors, such as synaptic 5-HT2A and glial 5-HT5A. To determine whether fluoxetine can affect developing neural circuits independent of serotonergic innervation from the dorsal and medial raphe nuclei, we treated cortical neurons and spheroids with fluoxetine. Fluoxetine alters neurite formation in a dose-dependent fashion. Intriguingly, in cortical spheroids, neither acute nor chronic fluoxetine significantly altered excitatory synapse formation. However, only acute, but not chronic fluoxetine exposure altered inhibitory synaptogenesis. Finally, fluoxetine reversibly suppresses neuronal activity in a dose-dependent manner. These results demonstrate that fluoxetine can acutely alter synaptic function in developing neural circuits, but the effects were not long-lasting. This work provides a foundation for future studies to combine serotonergic innervation with cortical spheroids and assess the contributions of fluoxetine-induced alterations in serotonin levels to brain development

Tafeln zur Berechnung der Coordinaten von Polygon- und Dreieck-Punkten niederer Ordnung

entworfen und herausgegeben von D.W. UlffersHandschriftliches Exlibris: "1851. Forstmeister Kopp in Frauenfeld 003887691_0001 Exemplar der ETH-BIBExlibrisstempel: "Sammlung der Schweiz. Forstschule" 003889758_0001 Exemplar der ETH-BI

Ernst II. von Sachsen-Coburg-Gotha, Herzog (1818-1893)

Lithogr. von M. Ulffer