23 research outputs found
Cucurbit[8]uril induced heterodimerization of methylviologen and naphthalene functionalized proteins
Cucurbit[8]uril is a supramolecular inducer of protein heterodimerization for proteins appended with methylviologen and naphthalene host elements. Two sets of fluorescent protein pairs, which visualize the specific protein assembly process, enabled the interplay of the supramolecular elements with the proteins to be established
Immobilization of ferrocene-modified SNAP-fusion proteins
Abstract: The supramolecular assembly of proteins on surfaces has been investigated via the site-selective incorporation of a supramolecular moiety on proteins. To this end, fluorescent proteins have been site-selectively labeled with ferrocenes, as supramolecular guest moieties, via SNAP-tag technology. The assembly of guest-functionalized SNAP-fusion proteins on cyclodextrin-and cucurbi
Incorporating Bacteria as a Living Component in Supramolecular Self-Assembled Monolayers through Dynamic Nanoscale Interactions
Dual Molecular Recognition Leading to a Protein–Polymer Conjugate and Further Self-Assembly
Patchy Supramolecules as Versatile Tools To Probe Hydrophobicity in Nanoglobular Systems
“Supramolecular Circuitry”: Three Chemiluminescent, Cucurbit[7]uril-Controlled On/Off Switches
Elucidating the Structure of Poly(dopamine)
Herein we propose a new structure for poly(dopamine), a synthetic eumelanin that has found broad utility as an antifouling agent. Commercially available 3-hydroxytyramine hydrochloride (dopamine HCl) was polymerized under aerobic, aqueous conditions using tris(hydroxymethyl)aminomethane (TRIS) as a basic polymerization initiator, affording a darkly colored powder product upon isolation. The polymer was analyzed using a variety of solid state spectroscopic and crystallographic techniques. Collectively, the data showed that in contrast to previously proposed models, poly(dopamine) is not a covalent polymer but instead a supramolecular aggregate of monomers (consisting primarily of 5,6-dihydroxyindoline and its dione derivative) that are held together through a combination of charge transfer, pi-stacking, and hydrogen bonding interactions