4 research outputs found

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

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    This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

    Smallholder production of agroforestry germplasm: experiences and lessons from Brazil, Costa Rica, Mexico and Peru

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    Smallholders often cannot obtain the agroforestry germplasm they require. It has been suggested that commercial smallholder production of germplasm could help resolve this problem, while securing benefits such as genetic conservation and income generation. We evaluate four such initiatives. We found that worthwhile income was generated, and we suggest ways that returns could be increased.\ud We also found that the initiatives had contributed to genetic conservation, although we argue that such outcomes may be more elusive for timber trees than for non-destructively harvested tree crops. The four initiatives fell short of the “win-win” ideal of germplasm production, i.e. that of smallholders profiting through sale of livelihood-enhancing germplasm to other smallholders, principally because sales tend to be to industrial or institutional clients rather than to smallholders. We suggest that, for the potential of smallholder germplasm production to be fully evaluated,\ud detailed characterization of farmer demand and willingness to pay for agroforestry germplasm is needed

    COVID-19 vaccine safety during the antenatal period in women with idiopathic inflammatory myopathies

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    COVID-19 breakthrough infections in type 1 diabetes mellitus: a cross-sectional study by the COVID-19 Vaccination in Autoimmune Diseases (COVAD) Group

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    To investigate the frequency, profile, and severity of COVID-19 breakthrough infections (BI) in patients with type I diabetes mellitus (T1DM) compared to healthy controls (HC) after vaccination. The second COVID-19 Vaccination in Autoimmune Diseases (COVAD-2) survey is a multinational cross-sectional electronic survey which has collected data on patients suffering from various autoimmune diseases including T1DM. We performed a subgroup analysis on this cohort to investigate COVID-19 BI characteristics in patients with T1DM. Logistic regression with propensity score matching analysis was performed. A total of 9595 individuals were included in the analysis, with 100 patients having T1DM. Among the fully vaccinated cohort, 16 (16%) T1DM patients had one BI and 2 (2%) had two BIs. No morbidities or deaths were reported, except for one patient who required hospitalization with oxygen without admission to intensive care. The frequency, clinical features, and severity of BIs were not significantly different between T1DM patients and HCs after adjustment for confounding factors. Our study did not show any statistically significant differences in the frequency, symptoms, duration, or critical care requirements between T1DM and HCs after COVID-19 vaccination. Further research is needed to identify factors associated with inadequate vaccine response in patients with BIs, especially in patients with autoimmune diseases
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